The protein tyrosine phosphatase PRL-2 interacts with the magnesium transporter CNNM3 to promote oncogenesis

Purification, crystallization and preliminary crystallographic analysis of the CBS-domain pair of cyclin M2 (CNNM2)

(2012) Inmaculada Gómez-García et al.   Acta Crystallographica Section F-Structural Biology and Crystallization Communications

Impact of Oncogenic Protein Tyrosine Phosphatases in Cancer

(2012) Serge Hardy et al.   Anti-Cancer Agents in Medicinal Chemistry

Magnesium and its transporters in cancer: a novel paradigm in tumour development

(2012) Federica I. Wolf et al.   CLINICAL SCIENCE

Molecular mechanisms of the PRL phosphatases

(2012) Pablo Rios et al.   FEBS Journal

Phosphatase of Regenerating Liver 2 (PRL2) Is Essential for Placental Development by Down-regulating PTEN (Phosphatase and Tensin Homologue Deleted on Chromosome 10) and Activating Akt Protein

(2012) Yuanshu Dong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Topology and Intracellular Processing of Cyclin M2 (CNNM2)

(2012) Jeroen H. F. de Baaij et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The phosphatase of regenerating liver 3 (PRL-3) promotes cell migration through Arf-activity-dependent stimulation of integrin  5 recycling

(2012) D. Krndija et al.   JOURNAL OF CELL SCIENCE

CNNM2, Encoding a Basolateral Protein Required for Renal Mg2+ Handling, Is Mutated in Dominant Hypomagnesemia

(2011) Marchel Stuiver et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human gene SLC41A1 encodes for the Na+/Mg2+ exchanger

(2011) Martin Kolisek et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

H3K27 demethylation by JMJD3 at a poised enhancer of anti-apoptotic geneBCL2determines ERα ligand dependency

(2011) Amy Svotelis et al.   EMBO JOURNAL

Vaccinia H1-related Phosphatase Is a Phosphatase of ErbB Receptors and Is Down-regulated in Non-small Cell Lung Cancer

(2011) Jiz-Yuh Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Second messenger role for Mg2+ revealed by human T-cell immunodeficiency

(2011) Feng-Yen Li et al.   NATURE

Metastasis-associated phosphatase PRL-2 regulates tumor cell migration and invasion

(2011) Y Wang et al.   ONCOGENE

Overexpression of the Protein Tyrosine Phosphatase PRL-2 Correlates with Breast Tumor Formation and Progression

(2010) S. Hardy et al.   CANCER RESEARCH

PRL-3 phosphatase and cancer metastasis

(2010) Abdul Qader O. Al-Aidaroos et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Magnesium deprivation inhibits a MEK–ERK cascade and cell proliferation in renal epithelial Madin-Darby canine kidney cells

(2010) Akira Ikari et al.   LIFE SCIENCES

Genome-Wide Association Studies of Serum Magnesium, Potassium, and Sodium Concentrations Identify Six Loci Influencing Serum Magnesium Levels

(2010) Tamra E. Meyer et al.   PLoS Genetics

Molecular identification of ancient and modern mammalian magnesium transporters

(2009) Gary A. Quamme   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Enzyme Activity of Phosphatase of Regenerating Liver Is Controlled by the Redox Environment and Its C-Terminal Residues

(2009) Andria L. Skinner et al.   BIOCHEMISTRY

PRL-3 promotes the motility, invasion, and metastasis of LoVo colon cancer cells through PRL-3-integrin β1-ERK1/2 and-MMP2 signaling

(2009) Lirong Peng et al.   Molecular Cancer

Transient receptor potential melastatin 6 and 7 channels, magnesium transport, and vascular biology: implications in hypertension

(2008) Rhian M. Touyz   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Small interfering RNA-mediated knockdown of PRL phosphatases results in altered Akt phosphorylation and reduced clonogenicity of pancreatic cancer cells

(2008) B. Stephens et al.   MOLECULAR CANCER THERAPEUTICS