标题
Towards novel paradigms for cancer therapy
作者
关键词
-
出版物
ONCOGENE
Volume 30, Issue 1, Pages 1-20
出版商
Springer Nature
发表日期
2010-10-11
DOI
10.1038/onc.2010.460
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Phase II trial of mapatumumab, a fully human agonistic monoclonal antibody that targets and activates the tumour necrosis factor apoptosis-inducing ligand receptor-1 (TRAIL-R1), in patients with refractory colorectal cancer
- (2010) T Trarbach et al. BRITISH JOURNAL OF CANCER
- Acquired and innate resistance to the cancer-specific apoptosis-inducing Cytokine, mda-7/IL-24: Not insurmountable therapeutic problems
- (2010) Devanand Sarkar et al. CANCER BIOLOGY & THERAPY
- Multivalent DR5 Peptides Activate the TRAIL Death Pathway and Exert Tumoricidal Activity
- (2010) V. Pavet et al. CANCER RESEARCH
- Thelet-7microRNA reduces tumor growth in mouse models of lung cancer
- (2010) Aurora Esquela-Kerscher et al. CELL CYCLE
- Dependence receptors: Mechanisms of an announced death
- (2010) Chantal Thibert et al. CELL CYCLE
- Inhibitors of Lactate Dehydrogenase Isoforms and their Therapeutic Potentials
- (2010) C. Granchi et al. CURRENT MEDICINAL CHEMISTRY
- Small-molecule pan-IAP antagonists: a patent review
- (2010) John A Flygare et al. EXPERT OPINION ON THERAPEUTIC PATENTS
- Chemoprevention of colorectal cancer by targeting APC-deficient cells for apoptosis
- (2010) Ling Zhang et al. NATURE
- Dependence receptors: a new paradigm in cell signaling and cancer therapy
- (2010) D Goldschneider et al. ONCOGENE
- Targeting cancer by transcriptional control in cancer gene therapy and viral oncolysis
- (2009) Dominik E. Dorer et al. ADVANCED DRUG DELIVERY REVIEWS
- Phase I and pharmacokinetic study of lexatumumab (HGS-ETR2) given every 2 weeks in patients with advanced solid tumors
- (2009) H. A. Wakelee et al. ANNALS OF ONCOLOGY
- Is TRAIL the holy grail of cancer therapy?
- (2009) Thomas Newsom-Davis et al. APOPTOSIS
- Mechanisms of anti-cancer action and pharmacology of clofarabine
- (2009) Anna Zhenchuk et al. BIOCHEMICAL PHARMACOLOGY
- miRNA deregulation by epigenetic silencing disrupts suppression of the oncogene PLAG1 in chronic lymphocytic leukemia
- (2009) C. P. Pallasch et al. BLOOD
- Curing APL: Differentiation or Destruction?
- (2009) Scott C. Kogan CANCER CELL
- Growth Factor-Antagonized Rexinoid Apoptosis Involves Permissive PPARγ/RXR Heterodimers to Activate the Intrinsic Death Pathway by NO
- (2009) Pattabhiraman Shankaranarayanan et al. CANCER CELL
- miR-221&222 Regulate TRAIL Resistance and Enhance Tumorigenicity through PTEN and TIMP3 Downregulation
- (2009) Michela Garofalo et al. CANCER CELL
- Epigenetic Repression of microRNA-129-2 Leads to Overexpression of SOX4 Oncogene in Endometrial Cancer
- (2009) Y.-W. Huang et al. CANCER RESEARCH
- Principles of Cancer Therapy: Oncogene and Non-oncogene Addiction
- (2009) Ji Luo et al. CELL
- Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening
- (2009) Piyush B. Gupta et al. CELL
- The Emerging Therapeutic Potential of Histone Methyltransferase and Demethylase Inhibitors
- (2009) Astrid Spannhoff et al. ChemMedChem
- Anti-epidermal growth factor receptor monoclonal antibodies in cancer therapy
- (2009) E. Martinelli et al. CLINICAL AND EXPERIMENTAL IMMUNOLOGY
- A Single Recombinant Adenovirus Expressing p53 and p21-targeting Artificial microRNAs Efficiently Induces Apoptosis in Human Cancer Cells
- (2009) M. Idogawa et al. CLINICAL CANCER RESEARCH
- Mapatumumab, a Fully Human Agonistic Monoclonal Antibody That Targets TRAIL-R1, in Combination with Gemcitabine and Cisplatin: a Phase I Study
- (2009) C. H. Mom et al. CLINICAL CANCER RESEARCH
- Therapy-induced PML/RARA Proteolysis and Acute Promyelocytic Leukemia Cure
- (2009) R. Nasr et al. CLINICAL CANCER RESEARCH
- Netrin-1 and its dependence receptors as original targets for cancer therapy
- (2009) Patrick Mehlen et al. CURRENT OPINION IN ONCOLOGY
- Inhibition of Endothelial Cell Apoptosis by Netrin-1 during Angiogenesis
- (2009) Marie Castets et al. DEVELOPMENTAL CELL
- TNF-related apoptosis-inducing ligand (TRAIL): A new path to anti-cancer therapies
- (2009) Peter A. Holoch et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Proteins selectively killing tumor cells
- (2009) Mathieu H.M. Noteborn EUROPEAN JOURNAL OF PHARMACOLOGY
- Acute myelogenous leukemia
- (2009) Joshua L. Shipley et al. EXPERIMENTAL HEMATOLOGY
- PTD4-apoptin protein therapy inhibits tumor growthin vivo
- (2009) Jun Sun et al. INTERNATIONAL JOURNAL OF CANCER
- Oncolytic virus therapy for prostate cancer
- (2009) Hiroshi Fukuhara et al. INTERNATIONAL JOURNAL OF UROLOGY
- Mapatumumab, an Antibody Targeting TRAIL-R1, in Combination With Paclitaxel and Carboplatin in Patients With Advanced Solid Malignancies: Results of a Phase I and Pharmacokinetic Study
- (2009) Stephen Leong et al. JOURNAL OF CLINICAL ONCOLOGY
- Histone Deacetylase Inhibitors in Cancer Therapy
- (2009) Andrew A. Lane et al. JOURNAL OF CLINICAL ONCOLOGY
- The Adenovirus E4orf4 Protein Induces G2/M Arrest and Cell Death by Blocking Protein Phosphatase 2A Activity Regulated by the B55 Subunit
- (2009) S. Li et al. JOURNAL OF VIROLOGY
- Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia
- (2009) A Hochhaus et al. LEUKEMIA
- Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution
- (2009) Sohrab P. Shah et al. NATURE
- The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs
- (2009) Helena Persson et al. NATURE CELL BIOLOGY
- Biomarkers of response and resistance to antiangiogenic therapy
- (2009) Rakesh K. Jain et al. Nature Reviews Clinical Oncology
- Adverse effects of anticancer agents that target the VEGF pathway
- (2009) Helen X. Chen et al. Nature Reviews Clinical Oncology
- Targeting angiogenesis: progress with anti-VEGF treatment with large molecules
- (2009) Axel Grothey et al. Nature Reviews Clinical Oncology
- Factors underlying sensitivity of cancers to small-molecule kinase inhibitors
- (2009) Pasi A. Jänne et al. NATURE REVIEWS DRUG DISCOVERY
- Tumour-initiating cells: challenges and opportunities for anticancer drug discovery
- (2009) Bin-Bing S. Zhou et al. NATURE REVIEWS DRUG DISCOVERY
- Programmed Cell Death Pathways and Current Antitumor Targets
- (2009) Mei Lan Tan et al. PHARMACEUTICAL RESEARCH
- Changes in Proteasome Structure and Function Caused by HAMLET in Tumor Cells
- (2009) Lotta Gustafsson et al. PLoS One
- Effects of the sesquiterpene lactone parthenolide on prostate tumor-initiating cells: An integrated molecular profiling approach
- (2009) Brian T. Kawasaki et al. PROSTATE
- DNA Polymerases as Therapeutic Targets†
- (2008) Anthony J. Berdis BIOCHEMISTRY
- Discovery of agents that eradicate leukemia stem cells using an in silico screen of public gene expression data
- (2008) D. C. Hassane et al. BLOOD
- Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells
- (2008) Zeng-Jie Yang et al. CANCER CELL
- Methylation Mediated Silencing of MicroRNA-1 Gene and Its Role in Hepatocellular Carcinogenesis
- (2008) J. Datta et al. CANCER RESEARCH
- TRAIL induces proliferation of human glioma cells by c-FLIPL-mediated activation of ERK1/2
- (2008) U. Vilimanovich et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- A Phase 1 Study of Mapatumumab (Fully Human Monoclonal Antibody to TRAIL-R1) in Patients with Advanced Solid Malignancies
- (2008) S. J. Hotte et al. CLINICAL CANCER RESEARCH
- Polymorphisms in Cyclooxygenase-2 and Epidermal Growth Factor Receptor Are Associated with Progression-Free Survival Independent of K-ras in Metastatic Colorectal Cancer Patients Treated with Single-Agent Cetuximab
- (2008) G. Lurje et al. CLINICAL CANCER RESEARCH
- Killing of human melanoma cells induced by activation of class I interferon-regulated signaling pathways via MDA-7/IL-24
- (2008) Suhendan Ekmekcioglu et al. CYTOKINE
- TRAIL receptor-targeted therapeutics: Resistance mechanisms and strategies to avoid them
- (2008) A THORBURN et al. DRUG RESISTANCE UPDATES
- Ad-MDA-7; INGN 241: a review of preclinical and clinical experience
- (2008) Robert Eager et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Gene therapy progress and prospects cancer: oncolytic viruses
- (2008) T-C Liu et al. GENE THERAPY
- HAMLET (human α-lactalbumin made lethal to tumor cells) triggers autophagic tumor cell death
- (2008) Sonja Aits et al. INTERNATIONAL JOURNAL OF CANCER
- Wild-TypeBRAFIs Required for Response to Panitumumab or Cetuximab in Metastatic Colorectal Cancer
- (2008) Federica Di Nicolantonio et al. JOURNAL OF CLINICAL ONCOLOGY
- Inhibitor of apoptosis proteins in hematological malignancies
- (2008) S Fulda LEUKEMIA
- Phase 2 study of mapatumumab, a fully human agonistic monoclonal antibody which targets and activates the TRAIL receptor-1, in patients with advanced non-small cell lung cancer
- (2008) F. Anthony Greco et al. LUNG CANCER
- TRAIL-induced survival and proliferation of SCLC cells is mediated by ERK and dependent on TRAIL-R2/DR5 expression in the absence of caspase-8
- (2008) Larisa L. Belyanskaya et al. LUNG CANCER
- Identification of cells initiating human melanomas
- (2008) Tobias Schatton et al. NATURE
- Efficient tumour formation by single human melanoma cells
- (2008) Elsa Quintana et al. NATURE
- Eradication of acute promyelocytic leukemia-initiating cells through PML-RARA degradation
- (2008) Rihab Nasr et al. NATURE MEDICINE
- BCL-2 family antagonists for cancer therapy
- (2008) Guillaume Lessene et al. NATURE REVIEWS DRUG DISCOVERY
- K-rasMutations and Benefit from Cetuximab in Advanced Colorectal Cancer
- (2008) Christos S. Karapetis et al. NEW ENGLAND JOURNAL OF MEDICINE
- Epigenetics in Cancer
- (2008) Manel Esteller NEW ENGLAND JOURNAL OF MEDICINE
- The adenovirus E4orf4 protein induces growth arrest and mitotic catastrophe in H1299 human lung carcinoma cells
- (2008) S Li et al. ONCOGENE
- Apoptin: Therapeutic Potential of an Early Sensor of Carcinogenic Transformation
- (2007) Claude Backendorf et al. Annual Review of Pharmacology and Toxicology
- Non-coding RNAs, epigenetics and complexity
- (2007) Fabrício F. Costa GENE
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started