The small molecule Retro-1 enhances the pharmacological actions of antisense and splice switching oligonucleotides

The Chemistry and Biology of Oligonucleotide Conjugates

(2012) R. L. Juliano et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nucleic Acid Delivery: The Missing Pieces of the Puzzle?

(2012) Juliane Nguyen et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorescent Peptide–PNA Chimeras for Imaging Monoamine Oxidase A mRNA in Neuronal Cells

(2012) Dalip Sethi et al.   BIOCONJUGATE CHEMISTRY

Single-Stranded siRNAs Activate RNAi in Animals

(2012) Walt F. Lima et al.   CELL

siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat

(2012) M. Al Soraj et al.   JOURNAL OF CONTROLLED RELEASE

Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy

(2012) G. C. Kendall et al.   Science Translational Medicine

Small Molecule Inhibition of RISC Loading

(2011) Grace S. Tan et al.   ACS Chemical Biology

A practical guide to evaluating colocalization in biological microscopy

(2011) Kenneth W. Dunn et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A brief review of DNA and RNA chemical synthesis: Figure 1

(2011) Marvin H. Caruthers   BIOCHEMICAL SOCIETY TRANSACTIONS

Multivalent Cyclic RGD Conjugates for Targeted Delivery of Small Interfering RNA

(2011) Md. Rowshon Alam et al.   BIOCONJUGATE CHEMISTRY

Cellular Uptake and Intracellular Trafficking of Antisense and siRNA Oligonucleotides

(2011) Rudolph L. Juliano et al.   BIOCONJUGATE CHEMISTRY

Current progress of siRNA/shRNA therapeutics in clinical trials

(2011) John C. Burnett et al.   Biotechnology Journal

Protein transduction domain delivery of therapeutic macromolecules

(2011) Arjen van den Berg et al.   CURRENT OPINION IN BIOTECHNOLOGY

The Many Faces of RNAi

(2011) René F. Ketting   DEVELOPMENTAL CELL

Antisense drug discovery and development

(2011) Tsuyoshi Yamamoto et al.   Future Medicinal Chemistry

Inhibition of HIV transmission in human cervicovaginal explants and humanized mice using CD4 aptamer-siRNA chimeras

(2011) Lee Adam Wheeler et al.   JOURNAL OF CLINICAL INVESTIGATION

Unconventional internalization mechanisms underlying functional delivery of antisense oligonucleotides via cationic lipoplexes and polyplexes

(2011) Xin Ming et al.   JOURNAL OF CONTROLLED RELEASE

Versatile Site-Specific Conjugation of Small Molecules to siRNA Using Click Chemistry

(2011) Takeshi Yamada et al.   JOURNAL OF ORGANIC CHEMISTRY

Silencing disease genes in the laboratory and the clinic

(2011) Jonathan K Watts et al.   JOURNAL OF PATHOLOGY

Mechanisms of single-stranded phosphorothioate modified antisense oligonucleotide accumulation in hepatocytes

(2011) Erich Koller et al.   NUCLEIC ACIDS RESEARCH

PepFect 14, a novel cell-penetrating peptide for oligonucleotide delivery in solution and as solid formulation

(2011) Kariem Ezzat et al.   NUCLEIC ACIDS RESEARCH

Development and utilization of non-coding RNA–small molecule interactions

(2011) Wesleigh E. Georgianna et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Role of Rab GTPases in Membrane Traffic and Cell Physiology

(2011) Alex H. Hutagalung et al.   PHYSIOLOGICAL REVIEWS

Antitumorigenic potential of STAT3 alternative splicing modulation

(2011) F. Zammarchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Inhibition of Retrograde Transport Protects Mice from Lethal Ricin Challenge

(2010) Bahne Stechmann et al.   CELL

Molecules, mechanisms, and cellular roles of clathrin-independent endocytosis

(2010) Mark T Howes et al.   CURRENT OPINION IN CELL BIOLOGY

Gene Targeting and Expression Modulation by Peptide Nucleic Acids (PNA)

(2010) Peter E. Nielsen   CURRENT PHARMACEUTICAL DESIGN

Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: a focus on toxicogenomics

(2010) Saghir Akhtar   Expert Opinion on Drug Metabolism & Toxicology

Endosomal escape pathways for delivery of biologicals

(2010) Amir K. Varkouhi et al.   JOURNAL OF CONTROLLED RELEASE

Small Molecule Modifiers of MicroRNA miR-122 Function for the Treatment of Hepatitis C Virus Infection and Hepatocellular Carcinoma

(2010) Douglas D. Young et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeted Delivery of RNAi Therapeutics With Endogenous and Exogenous Ligand-Based Mechanisms

(2010) Akin Akinc et al.   MOLECULAR THERAPY

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Anti-tumor activity of splice-switching oligonucleotides

(2010) John A. Bauman et al.   NUCLEIC ACIDS RESEARCH

Intracellular delivery of an antisense oligonucleotide via endocytosis of a G protein-coupled receptor

(2010) Xin Ming et al.   NUCLEIC ACIDS RESEARCH

Lipid-like materials for low-dose, in vivo gene silencing

(2010) K. T. Love et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipid-based systemic delivery of siRNA

(2009) Yu-Cheng Tseng et al.   ADVANCED DRUG DELIVERY REVIEWS

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

Chemical vectors for gene delivery: a current review on polymers, peptides and lipids containing histidine or imidazole as nucleic acids carriers

(2009) Patrick Midoux et al.   BRITISH JOURNAL OF PHARMACOLOGY

Phosphorothioate-Stimulated Uptake of siRNA by Mammalian Cells: A Novel Route for Delivery

(2009) Anke Detzer et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Lipid-based nanotherapeutics for siRNA delivery

(2009) A. Schroeder et al.   JOURNAL OF INTERNAL MEDICINE

Biological Barriers to Therapy with Antisense and siRNA Oligonucleotides

(2009) R. Juliano et al.   MOLECULAR PHARMACEUTICS

Small RNAs in transcriptional gene silencing and genome defence

(2009) Danesh Moazed   NATURE

In vivo delivery of siRNA to immune cells by conjugation to a TLR9 agonist enhances antitumor immune responses

(2009) Marcin Kortylewski et al.   NATURE BIOTECHNOLOGY

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Rab GTPases as coordinators of vesicle traffic

(2009) Harald Stenmark   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Biological Effect of an Antisense Oligonucleotide Depends on Its Route of Endocytosis and Trafficking

(2009) Md. Rowshon Alam et al.   OLIGONUCLEOTIDES

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

Transport of Dicationic Drugs Pentamidine and Furamidine by Human Organic Cation Transporters

(2008) X. Ming et al.   DRUG METABOLISM AND DISPOSITION

Intracellular delivery of an anionic antisense oligonucleotide via receptor-mediated endocytosis

(2008) Md Rowshon Alam et al.   NUCLEIC ACIDS RESEARCH

Improved cell-penetrating peptide–PNA conjugates for splicing redirection in HeLa cells and exon skipping in mdx mouse muscle

(2008) Gabriela D. Ivanova et al.   NUCLEIC ACIDS RESEARCH

The Art of Assembly

(2008) F. Szoka   SCIENCE