Cationic nanosystems for the delivery of small interfering ribonucleic acid therapeutics: a focus on toxicogenomics

RNA Targeting Therapeutics: Molecular Mechanisms of Antisense Oligonucleotides as a Therapeutic Platform

(2010) C. Frank Bennett et al.   Annual Review of Pharmacology and Toxicology

Evidence of RNAi in humans from systemically administered siRNA via targeted nanoparticles

(2010) Mark E. Davis et al.   NATURE

Rational design of cationic lipids for siRNA delivery

(2010) Sean C Semple et al.   NATURE BIOTECHNOLOGY

RNA Interference: From Basic Research to Therapeutic Applications

(2009) Jens Kurreck   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanomedicine-Challenge and Perspectives

(2009) Kristina Riehemann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Internally Cationic Polyamidoamine PAMAM-OH Dendrimers for siRNA Delivery: Effect of the Degree of Quaternization and Cancer Targeting

(2009) Mahesh L. Patil et al.   BIOMACROMOLECULES

Degradable polyethylenimines as DNA and small interfering RNA carriers

(2009) D Jere et al.   Expert Opinion on Drug Delivery

Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

(2009) Oleh Taratula et al.   JOURNAL OF CONTROLLED RELEASE

Neuroprotection by biodegradable PAMAM ester (e-PAM-R)-mediated HMGB1 siRNA delivery in primary cortical cultures and in the postischemic brain

(2009) Il-Doo Kim et al.   JOURNAL OF CONTROLLED RELEASE

Size and shape effects in the biodistribution of intravascularly injected particles

(2009) P. Decuzzi et al.   JOURNAL OF CONTROLLED RELEASE

Oral delivery of siRNA and antisense oligonucleotides

(2009) Saghir Akhtar   JOURNAL OF DRUG TARGETING

Lipid-based nanotherapeutics for siRNA delivery

(2009) A. Schroeder et al.   JOURNAL OF INTERNAL MEDICINE

Pegylated nanoliposomes remote-loaded with the antioxidant tempamine ameliorate experimental autoimmune encephalomyelitis

(2009) Pablo Kizelsztein et al.   JOURNAL OF NEUROIMMUNOLOGY

Nonviral siRNA Delivery to the Lung: Investigation of PEG−PEI Polyplexes and Their In Vivo Performance

(2009) Olivia M. Merkel et al.   MOLECULAR PHARMACEUTICS

The First Targeted Delivery of siRNA in Humans via a Self-Assembling, Cyclodextrin Polymer-Based Nanoparticle: From Concept to Clinic

(2009) Mark E. Davis   MOLECULAR PHARMACEUTICS

Orally delivered siRNA targeting macrophage Map4k4 suppresses systemic inflammation

(2009) Myriam Aouadi et al.   NATURE

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA

(2009) Kim A. Woodrow et al.   NATURE MATERIALS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application

(2009) Aimee L. Jackson et al.   NATURE REVIEWS DRUG DISCOVERY

siRNA and Innate Immunity

(2009) Marjorie Robbins et al.   OLIGONUCLEOTIDES

Liposomes and nanoparticles: nanosized vehicles for drug delivery in cancer

(2009) Yogeshkumar Malam et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Toxicogenomics to Improve Comprehension of the Mechanisms Underlying Responses of In Vitro and In Vivo Systems to Nanomaterials: A Review

(2008) Anna Poma et al.   CURRENT GENOMICS

Dendrimers as versatile platform in drug delivery applications

(2008) Sonke Svenson   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

The role of macromolecular architecture in passively targeted polymeric carriers for drug and gene delivery

(2008) Scott M. Grayson et al.   JOURNAL OF DRUG TARGETING

Drug delivery of siRNA therapeutics: potentials and limits of nanosystems

(2008) Daniela Reischl et al.   Nanomedicine-Nanotechnology Biology and Medicine

Mechanisms and strategies for effective delivery of antisense and siRNA oligonucleotides

(2008) R. Juliano et al.   NUCLEIC ACIDS RESEARCH

Microarray Analysis of the Toxicogenomics and the Genotoxic Potential of a Cationic Lipid-Based Gene Delivery Nanosystem in Human Alveolar Epithelial A549 Cells

(2008) Yadollah Omidi et al.   TOXICOLOGY MECHANISMS AND METHODS