The THO complex cooperates with the nuclear RNA surveillance machinery to control small nucleolar RNA expression

Architecture and nucleic acids recognition mechanism of the THO complex, an mRNP assembly factor

(2012) Álvaro Peña et al.   EMBO JOURNAL

New clues to understand the role of THO and other functionally related factors in mRNP biogenesis

(2011) Rosa Luna et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Genome-wide function of THO/TREX in active genes prevents R-loop-dependent replication obstacles

(2011) Belén Gómez-González et al.   EMBO JOURNAL

The Prp19 complex is a novel transcription elongation factor required for TREX occupancy at transcribed genes

(2011) S. Chanarat et al.   GENES & DEVELOPMENT

A Pre-mRNA Degradation Pathway that Selectively Targets Intron-Containing Genes Requires the Nuclear Poly(A)-Binding Protein

(2011) Caroline Lemieux et al.   MOLECULAR CELL

The export factor Yra1 modulates mRNA 3′ end processing

(2011) Sara A Johnson et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Identification of mRNAs that are spliced but not exported to the cytoplasm in the absence of THOC5 in mouse embryo fibroblasts

(2011) A. Guria et al.   RNA

Clr4/Suv39 and RNA Quality Control Factors Cooperate to Trigger RNAi and Suppress Antisense RNA

(2011) K. Zhang et al.   SCIENCE

Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

(2011) María S. Domínguez-Sánchez et al.   PLoS Genetics

The interface between transcription and mRNP export: From THO to THSC/TREX-2

(2010) Ana G. Rondón et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The human core exosome interacts with differentially localized processive RNases: hDIS3 and hDIS3L

(2010) Rafal Tomecki et al.   EMBO JOURNAL

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

(2010) K. Dufu et al.   GENES & DEVELOPMENT

Multifunctional factor ENY2 is associated with the THO complex and promotes its recruitment onto nascent mRNA

(2010) D. V. Kopytova et al.   GENES & DEVELOPMENT

The Nuclear Poly(A)-Binding Protein Interacts with the Exosome to Promote Synthesis of Noncoding Small Nucleolar RNAs

(2010) Jean-François Lemay et al.   MOLECULAR CELL

Analysis of a genome-wide set of gene deletions in the fission yeast Schizosaccharomyces pombe

(2010) Dong-Uk Kim et al.   NATURE BIOTECHNOLOGY

Proteomic and functional analysis of the noncanonical poly(A) polymerase Cid14

(2010) C. Keller et al.   RNA

Nuclear RNA surveillance: no sign of substrates tailing off

(2009) James T. Anderson et al.   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA

(2009) Jun Katahira et al.   EMBO JOURNAL

Eukaryotic snoRNAs: A paradigm for gene expression flexibility

(2009) Giorgio Dieci et al.   GENOMICS

A Methyltransferase-independent Function for Rmt3 in Ribosomal Subunit Homeostasis

(2009) Audrey Perreault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cotranscriptional recruitment of the nuclear poly(A)-binding protein Pab2 to nascent transcripts and association with translating mRNPs

(2009) C. Lemieux et al.   NUCLEIC ACIDS RESEARCH

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

(2009) Claudia Schneider et al.   NUCLEIC ACIDS RESEARCH

THO/Sub2p Functions to Coordinate 3′-End Processing with Gene-Nuclear Pore Association

(2008) Mathieu Rougemaille et al.   CELL

A Yeast Exosome Cofactor, Mpp6, Functions in RNA Surveillance and in the Degradation of Noncoding RNA Transcripts

(2008) L. Milligan et al.   MOLECULAR AND CELLULAR BIOLOGY

Polyadenylation Linked to Transcription Termination Directs the Processing of snoRNA Precursors in Yeast

(2008) Pawel Grzechnik et al.   MOLECULAR CELL

Nuclear mRNA Surveillance in THO/sub2 Mutants Is Triggered by Inefficient Polyadenylation

(2008) Cyril Saguez et al.   MOLECULAR CELL

Endonucleolytic RNA cleavage by a eukaryotic exosome

(2008) Alice Lebreton et al.   NATURE

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities

(2008) Daneen Schaeffer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Evidence for core exosome independent function of the nuclear exoribonuclease Rrp6p

(2008) Kevin P. Callahan et al.   NUCLEIC ACIDS RESEARCH