Genome Instability and Transcription Elongation Impairment in Human Cells Depleted of THO/TREX

The interface between transcription and mRNP export: From THO to THSC/TREX-2

(2010) Ana G. Rondón et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Activation-Induced Cytidine Deaminase Targets DNA at Sites of RNA Polymerase II Stalling by Interaction with Spt5

(2010) Rushad Pavri et al.   CELL

ATP is required for interactions between UAP56 and two conserved mRNA export proteins, Aly and CIP29, to assemble the TREX complex

(2010) K. Dufu et al.   GENES & DEVELOPMENT

Multifunctional factor ENY2 is associated with the THO complex and promotes its recruitment onto nascent mRNA

(2010) D. V. Kopytova et al.   GENES & DEVELOPMENT

Adaptor Aly and co-adaptor Thoc5 function in the Tap-p15-mediated nuclear export of HSP70 mRNA

(2009) Jun Katahira et al.   EMBO JOURNAL

The S-Phase Checkpoint Is Required To Respond to R-Loops Accumulated in THO Mutants

(2009) B. Gomez-Gonzalez et al.   MOLECULAR AND CELLULAR BIOLOGY

A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability

(2009) Renee D. Paulsen et al.   MOLECULAR CELL

Highly Transcribed RNA Polymerase II Genes Are Impediments to Replication Fork Progression in Saccharomyces cerevisiae

(2009) Anna Azvolinsky et al.   MOLECULAR CELL

Topoisomerase I suppresses genomic instability by preventing interference between replication and transcription

(2009) Sandie Tuduri et al.   NATURE CELL BIOLOGY

A Novel Tandem Reporter Quantifies RNA Polymerase II Termination in Mammalian Cells

(2009) Ayan Banerjee et al.   PLoS One

Biogenesis of mRNPs: integrating different processes in the eukaryotic nucleus

(2008) Rosa Luna et al.   CHROMOSOMA

The Iws1:Spt6:CTD complex controls cotranscriptional mRNA biosynthesis and HYPB/Setd2-mediated histone H3K36 methylation

(2008) S. M. Yoh et al.   GENES & DEVELOPMENT

Genome instability: a mechanistic view of its causes and consequences

(2008) Andrés Aguilera et al.   NATURE REVIEWS GENETICS

The splicing factor SC35 has an active role in transcriptional elongation

(2008) Shengrong Lin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Definition of global and transcript-specific mRNA export pathways in metazoans

(2007) N. G. Farny et al.   GENES & DEVELOPMENT