标题
Epigenetics, Autism Spectrum, and Neurodevelopmental Disorders
作者
关键词
Autism, Neurodevelopmental disorders, Rett, Prader-Willi, Angelman, Fragile X, Methylation, Acetylation, Histones
出版物
Neurotherapeutics
Volume 10, Issue 4, Pages 742-756
出版商
Springer Nature
发表日期
2013-10-09
DOI
10.1007/s13311-013-0227-0
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genome-wide analysis validates aberrant methylation in fragile X syndrome is specific to the FMR1locus
- (2013) Reid S Alisch et al. BMC Medical Genetics
- Paradoxical worsening of seizure activity with pregabalin in an adult with isodicentric 15 (IDIC-15) syndrome involving duplications of the GABRB3, GABRA5 and GABRG3 genes
- (2013) Alessandro Di Rocco et al. BMC Neurology
- X-Inactivation, Imprinting, and Long Noncoding RNAs in Health and Disease
- (2013) Jeannie T. Lee et al. CELL
- An AT-Hook Domain in MeCP2 Determines the Clinical Course of Rett Syndrome and Related Disorders
- (2013) Steven Andrew Baker et al. CELL
- Genetic syndromes caused by mutations in epigenetic genes
- (2013) María Berdasco et al. HUMAN GENETICS
- Systemic Delivery of MeCP2 Rescues Behavioral and Cellular Deficits in Female Mouse Models of Rett Syndrome
- (2013) S. K. Garg et al. JOURNAL OF NEUROSCIENCE
- Histone-Methyltransferase MLL2 (KMT2B) Is Required for Memory Formation in Mice
- (2013) C. Kerimoglu et al. JOURNAL OF NEUROSCIENCE
- Translating dosage compensation to trisomy 21
- (2013) Jun Jiang et al. NATURE
- MeCP2 modulates gene expression pathways in astrocytes
- (2013) Dag H Yasui et al. Molecular Autism
- The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)
- (2012) Asha L. Bhakar et al. Annual Review of Neuroscience
- The Expanding Role of MBD Genes in Autism: Identification of aMECP2Duplication and Novel Alterations inMBD5,MBD6, andSETDB1
- (2012) Holly N. Cukier et al. Autism Research
- MECP2 duplication syndrome in both genders
- (2012) Shino Shimada et al. BRAIN & DEVELOPMENT
- MeCP2 Binds to 5hmC Enriched within Active Genes and Accessible Chromatin in the Nervous System
- (2012) Marian Mellén et al. CELL
- SIRT1-mediated deacetylation of MeCP2 contributes to BDNF expression
- (2012) Loredana Zocchi et al. Epigenetics
- Trans-tail regulation of MLL4-catalyzed H3K4 methylation by H4R3 symmetric dimethylation is mediated by a tandem PHD of MLL4
- (2012) S. S. Dhar et al. GENES & DEVELOPMENT
- Ube3a-ATS is an atypical RNA polymerase II transcript that represses the paternal expression of Ube3a
- (2012) Linyan Meng et al. HUMAN MOLECULAR GENETICS
- Kabuki syndrome revisited
- (2012) Yemisi Bokinni JOURNAL OF HUMAN GENETICS
- Isoform-Specific Toxicity of Mecp2 in Postmitotic Neurons: Suppression of Neurotoxicity by FoxG1
- (2012) S. G. Dastidar et al. JOURNAL OF NEUROSCIENCE
- Absence of deletion and duplication of MLL2 and KDM6A genes in a large cohort of patients with Kabuki syndrome
- (2012) Manuela Priolo et al. MOLECULAR GENETICS AND METABOLISM
- Wild-type microglia arrest pathology in a mouse model of Rett syndrome
- (2012) Noël C. Derecki et al. NATURE
- Global identification of MLL2-targeted loci reveals MLL2's role in diverse signaling pathways
- (2012) C. Guo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Deletion of KDM6A, a Histone Demethylase Interacting with MLL2, in Three Patients with Kabuki Syndrome
- (2011) Damien Lederer et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genetics and epigenetics of the X chromosome
- (2011) Céline Morey et al. Annals of the New York Academy of Sciences
- The Role of MeCP2 in the Brain
- (2011) Jacky Guy et al. Annual Review of Cell and Developmental Biology
- Molecular Mechanisms of Fragile X Syndrome: A Twenty-Year Perspective
- (2011) Michael R. Santoro et al. Annual Review of Pathology-Mechanisms of Disease
- Genetic Heritability and Shared Environmental Factors Among Twin Pairs With Autism
- (2011) Joachim Hallmayer ARCHIVES OF GENERAL PSYCHIATRY
- Epidemiology of Autism Spectrum Disorders in Adults in the Community in England
- (2011) Traolach S. Brugha et al. ARCHIVES OF GENERAL PSYCHIATRY
- The role of methyl-binding proteins in chromatin organization and epigenome maintenance
- (2011) A. Fournier et al. Briefings in Functional Genomics
- Genomic imprinting: recognition and marking of imprinted loci
- (2011) Lara K Abramowitz et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- How genetically heterogeneous is Kabuki syndrome?: MLL2 testing in 116 patients, review and analyses of mutation and phenotypic spectrum
- (2011) Siddharth Banka et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation
- (2011) G. P. Vicent et al. GENES & DEVELOPMENT
- The Chromatin-binding Protein HMGN1 Regulates the Expression of Methyl CpG-binding Protein 2 (MECP2) and Affects the Behavior of Mice
- (2011) Liron Abuhatzira et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autism Spectrum Disorders and Epigenetics
- (2011) Daria Grafodatskaya et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Topoisomerase inhibitors unsilence the dormant allele of Ube3a in neurons
- (2011) Hsien-Sung Huang et al. NATURE
- Genomic imprinting: the emergence of an epigenetic paradigm
- (2011) Anne C. Ferguson-Smith NATURE REVIEWS GENETICS
- Therapeutic Strategies in Fragile X Syndrome: Dysregulated mGluR Signaling and Beyond
- (2011) Christina Gross et al. NEUROPSYCHOPHARMACOLOGY
- Mutation spectrum of MLL2 in a cohort of kabuki syndrome patients
- (2011) Lucia Micale et al. Orphanet Journal of Rare Diseases
- Epigenetic Characterization of the FMR1 Gene and Aberrant Neurodevelopment in Human Induced Pluripotent Stem Cell Models of Fragile X Syndrome
- (2011) Steven D. Sheridan et al. PLoS One
- Increased Gene Dosage of Ube3a Results in Autism Traits and Decreased Glutamate Synaptic Transmission in Mice
- (2011) S. E. P. Smith et al. Science Translational Medicine
- Angelman syndrome: insights into genomic imprinting and neurodevelopmental phenotypes
- (2011) Angela M. Mabb et al. TRENDS IN NEUROSCIENCES
- TheMECP2duplication syndrome
- (2010) Melissa B. Ramocki et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- Prader-Willi syndrome and Angelman syndrome
- (2010) Karin Buiting AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS
- Abnormalities of cell packing density and dendritic complexity in the MeCP2 A140V mouse model of Rett syndrome/X-linked mental retardation
- (2010) Garilyn M Jentarra et al. BMC NEUROSCIENCE
- Differential Modeling of Fragile X Syndrome by Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
- (2010) Achia Urbach et al. Cell Stem Cell
- Paternally inherited microdeletion at 15q11.2 confirms a significant role for the SNORD116 C/D box snoRNA cluster in Prader–Willi syndrome
- (2010) Angela L Duker et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Exome sequencing identifies MLL2 mutations as a cause of Kabuki syndrome
- (2010) Sarah B Ng et al. NATURE GENETICS
- A Custody Battle for the Mind: Evidence for Extensive Imprinting in the Brain
- (2010) Jessica Tollkuhn et al. NEURON
- Induced pluripotent stem cell models of the genomic imprinting disorders Angelman and Prader–Willi syndromes
- (2010) Stormy J. Chamberlain et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High-Resolution Analysis of Parent-of-Origin Allelic Expression in the Mouse Brain
- (2010) C. Gregg et al. SCIENCE
- The Role of MeCP2 in Brain Development and Neurodevelopmental Disorders
- (2010) Michael L. Gonzales et al. Current Psychiatry Reports
- Histone Deacetylases Suppress CGG Repeat–Induced Neurodegeneration Via Transcriptional Silencing in Models of Fragile X Tremor Ataxia Syndrome
- (2010) Peter K. Todd et al. PLoS Genetics
- Incidence of Fragile X Syndrome by Newborn Screening for Methylated FMR1 DNA
- (2009) Bradford Coffee et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Recent advances in MeCP2 structure and functionThis paper is one of a selection of papers published in this Special Issue, entitled 29th Annual International Asilomar Chromatin and Chromosomes Conference, and has undergone the Journal’s usual peer review process.
- (2009) Kristopher C. Hite et al. Biochemistry and Cell Biology
- Monoallelic gene expression and mammalian evolution
- (2009) Barry Keverne BIOESSAYS
- Epigenetic influences on brain development and plasticity
- (2009) Michela Fagiolini et al. CURRENT OPINION IN NEUROBIOLOGY
- Angelman syndrome (AS, MIM 105830)
- (2009) Griet Van Buggenhout et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Genomic imprinting disorders in humans: a mini-review
- (2009) Merlin G. Butler JOURNAL OF ASSISTED REPRODUCTION AND GENETICS
- Novel variants identified in methyl-CpG-binding domain genes in autistic individuals
- (2009) Holly N. Cukier et al. NEUROGENETICS
- Partial reversal of Rett Syndrome-like symptoms in MeCP2 mutant mice
- (2009) Daniela Tropea et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mechanisms of imprinting of the Prader-Willi/Angelman region
- (2008) Bernhard Horsthemke et al. AMERICAN JOURNAL OF MEDICAL GENETICS PART A
- A Mechanistic View of Genomic Imprinting
- (2008) Ky Sha Annual Review of Genomics and Human Genetics
- MECP2promoter methylation and X chromosome inactivation in autism
- (2008) Raman P. Nagarajan et al. Autism Research
- Molecular implementation and physiological roles for histone H3 lysine 4 (H3K4) methylation
- (2008) Ali Shilatifard CURRENT OPINION IN CELL BIOLOGY
- Structural variation in Xq28: MECP2 duplications in 1% of patients with unexplained XLMR and in 2% of male patients with severe encephalopathy
- (2008) Dorien Lugtenberg et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- The loss of methyl-CpG binding protein 1 leads to autism-like behavioral deficits
- (2008) A. M. Allan et al. HUMAN MOLECULAR GENETICS
- Advances in autism genetics: on the threshold of a new neurobiology
- (2008) Brett S. Abrahams et al. NATURE REVIEWS GENETICS
- DNA methylation landscapes: provocative insights from epigenomics
- (2008) Miho M. Suzuki et al. NATURE REVIEWS GENETICS
- MECP2 genomic structure and function: insights from ENCODE
- (2008) J. Singh et al. NUCLEIC ACIDS RESEARCH
- MeCP2, a Key Contributor to Neurological Disease, Activates and Represses Transcription
- (2008) M. Chahrour et al. SCIENCE
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