Glycine Transporter Type 1 Occupancy by Bitopertin: a Positron Emission Tomography Study in Healthy Volunteers

Radiosynthesis of [5-[11C]methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methyl-ethoxy)-phenyl]-[5-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindol-2-yl]-methanone ([11C]RO5013853), a novel PET tracer for the glycine transporter type I (GlyT1)

(2011) Emmanuel Pinard et al.   JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS

Glycine reuptake inhibitor RG1678: A pharmacologic characterization of an investigational agent for the treatment of schizophrenia

(2011) Daniela Alberati et al.   NEUROPHARMACOLOGY

Translational characterization of [11C]GSK931145, a PET ligand for the glycine transporter type 1

(2011) Roger N. Gunn et al.   SYNAPSE

Selective GlyT1 Inhibitors: Discovery of [4-(3-Fluoro-5-trifluoromethylpyridin-2-yl)piperazin-1-yl][5-methanesulfonyl-2-((S)-2,2,2-trifluoro-1-methylethoxy)phenyl]methanone (RG1678), a Promising Novel Medicine To Treat Schizophrenia

(2010) Emmanuel Pinard et al.   JOURNAL OF MEDICINAL CHEMISTRY

Pharmacological characterisation of the GlyT-1 glycine transporter using two novel radioligands

(2010) Hugh J. Herdon et al.   NEUROPHARMACOLOGY

The Thalamic Reticular Nucleus and Schizophrenia

(2010) F. Ferrarelli et al.   SCHIZOPHRENIA BULLETIN

The synthesis and preclinical evaluation in rhesus monkey of [18F]MK-6577 and [11C]CMPyPB glycine transporter 1 positron emission tomography radiotracers

(2010) Terence G. Hamill et al.   SYNAPSE

Measuring Drug Occupancy in the Absence of a Reference Region: The Lassen Plot Re-Visited

(2009) Vincent J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Multi-graphical analysis of dynamic PET

(2009) Yun Zhou et al.   NEUROIMAGE

A consistent and efficient graphical analysis method to improve the quantification of reversible tracer binding in radioligand receptor dynamic PET studies

(2008) Yun Zhou et al.   NEUROIMAGE

A novel radioligand for glycine transporter 1: characterization and use in autoradiographic and in vivo brain occupancy studies

(2008) Zhizhen Zeng et al.   NUCLEAR MEDICINE AND BIOLOGY