标题
Imaging Brain Effects of APOE4 in Cognitively Normal Individuals Across the Lifespan
作者
关键词
Apolipoprotein ε4, Structural MRI, FDG-PET, Amyloid PET imaging, Preclinical stage, Aging
出版物
NEUROPSYCHOLOGY REVIEW
Volume 24, Issue 3, Pages 290-299
出版商
Springer Nature
发表日期
2014-08-21
DOI
10.1007/s11065-014-9263-8
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- APOE-epsilon4 and aging of medial temporal lobe gray matter in healthy adults older than 50 years
- (2014) Joy L. Taylor et al. NEUROBIOLOGY OF AGING
- 18F-fluorodeoxyglucose positron emission tomography, aging, and apolipoprotein E genotype in cognitively normal persons
- (2014) David S. Knopman et al. NEUROBIOLOGY OF AGING
- APOE 4 worsens hippocampal CA1 apical neuropil atrophy and episodic memory
- (2014) G. A. Kerchner et al. NEUROLOGY
- Amyloid and APOE 4 interact to influence short-term decline in preclinical Alzheimer disease
- (2014) E. C. Mormino et al. NEUROLOGY
- Association of hypometabolism and amyloid levels in aging, normal subjects
- (2014) V. J. Lowe et al. NEUROLOGY
- Functional Brain Connectivity Using fMRI in Aging and Alzheimer’s Disease
- (2014) Emily L. Dennis et al. NEUROPSYCHOLOGY REVIEW
- Effect of amyloid on memory and non-memory decline from preclinical to clinical Alzheimer’s disease
- (2013) Yen Ying Lim et al. BRAIN
- Common Variants in Psychiatric Risk Genes Predict Brain Structure at Birth
- (2013) R. C. Knickmeyer et al. CEREBRAL CORTEX
- Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study
- (2013) Victor L Villemagne et al. LANCET NEUROLOGY
- Apolipoprotein E and Alzheimer disease: risk, mechanisms and therapy
- (2013) Chia-Chen Liu et al. Nature Reviews Neurology
- The apolipoprotein E epsilon 4 allele is associated with ventricular expansion rate and surface morphology in dementia and normal aging
- (2013) Florence F. Roussotte et al. NEUROBIOLOGY OF AGING
- Mapping the effects of ApoE4, age and cognitive status on 18F-florbetapir PET measured regional cortical patterns of beta-amyloid density and growth
- (2013) Kelly R. Murphy et al. NEUROIMAGE
- Differential effects of the ApoE4 genotype on brain structure and function
- (2013) Silke Matura et al. NEUROIMAGE
- Amyloid imaging and CSF biomarkers in predicting cognitive impairment up to 7.5 years later
- (2013) C. M. Roe et al. NEUROLOGY
- Dissecting the Gene Dose-Effects of the APOE ε4 and ε2 Alleles on Hippocampal Volumes in Aging and Alzheimer’s Disease
- (2013) Christopher A. Hostage et al. PLoS One
- Neuroimaging biomarkers for Alzheimer's disease in asymptomatic APOE4 carriers
- (2013) G. Chételat et al. REVUE NEUROLOGIQUE
- Apolipoprotein E and Apolipoprotein E Receptors: Normal Biology and Roles in Alzheimer Disease
- (2013) D. M. Holtzman et al. Cold Spring Harbor Perspectives in Medicine
- Brain Differences in Infants at Differential Genetic Risk for Late-Onset Alzheimer Disease
- (2013) Douglas C. Dean et al. JAMA Neurology
- Aβ amyloid, cognition, and APOE genotype in healthy older adults
- (2012) Yen Ying Lim et al. Alzheimers & Dementia
- In vivo assessment of amyloid-β deposition in nondemented very elderly subjects
- (2012) Chester A. Mathis et al. ANNALS OF NEUROLOGY
- Alzheimer Mechanisms and Therapeutic Strategies
- (2012) Yadong Huang et al. CELL
- Accelerating Cortical Thinning: Unique to Dementia or Universal in Aging?
- (2012) Anders M. Fjell et al. CEREBRAL CORTEX
- Apolipoprotein E, Not Fibrillar -Amyloid, Reduces Cerebral Glucose Metabolism in Normal Aging
- (2012) W. J. Jagust et al. JOURNAL OF NEUROSCIENCE
- Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study
- (2012) Christopher M Clark et al. LANCET NEUROLOGY
- Apolipoprotein E ε4 and age effects on florbetapir positron emission tomography in healthy aging and Alzheimer disease
- (2012) Adam S. Fleisher et al. NEUROBIOLOGY OF AGING
- Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ε4 gene dose in cognitively normal adults: A cross-validation study using voxel-based multi-modal partial least squares
- (2012) Kewei Chen et al. NEUROIMAGE
- Stronger effect of amyloid load than APOE genotype on cognitive decline in healthy older adults
- (2012) Y. Y. Lim et al. NEUROLOGY
- Indicators of amyloid burden in a population-based study of cognitively normal elderly
- (2012) M. M. Mielke et al. NEUROLOGY
- -Amyloid burden in healthy aging: Regional distribution and cognitive consequences
- (2012) K. M. Rodrigue et al. NEUROLOGY
- Family History and APOE-4 Genetic Risk in Alzheimer’s Disease
- (2012) Markus Donix et al. NEUROPSYCHOLOGY REVIEW
- Reduced Hippocampal Volume in Healthy Young ApoE4 Carriers: An MRI Study
- (2012) Laurence O'Dwyer et al. PLoS One
- Posterior Cingulate Glucose Metabolism, Hippocampal Glucose Metabolism, and Hippocampal Volume in Cognitively Normal, Late-Middle-Aged Persons at 3 Levels of Genetic Risk for Alzheimer Disease
- (2012) Hillary D. Protas et al. JAMA Neurology
- Impact of apolipoprotein ɛ4–cerebrospinal fluid beta-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment
- (2011) Gloria C. Chiang et al. Alzheimers & Dementia
- Toward defining the preclinical stages of Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
- (2011) Reisa A. Sperling et al. Alzheimers & Dementia
- Design Considerations for Characterizing Psychiatric Trajectories Across the Lifespan: Application to Effects of APOE-ε4 on Cerebral Cortical Thickness in Alzheimer's Disease
- (2011) Wesley K. Thompson et al. AMERICAN JOURNAL OF PSYCHIATRY
- Amyloid-beta plaque growth in cognitively normal adults: Longitudinal [11C]Pittsburgh compound B data
- (2011) Andrei G. Vlassenko et al. ANNALS OF NEUROLOGY
- Longitudinal assessment of Aβ and cognition in aging and Alzheimer disease
- (2011) Victor L. Villemagne et al. ANNALS OF NEUROLOGY
- White matter integrity and vulnerability to Alzheimer's disease: Preliminary findings and future directions
- (2011) Brian T. Gold et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Episodic memory on the path to Alzheimer's disease
- (2011) Michela Gallagher et al. CURRENT OPINION IN NEUROBIOLOGY
- Use of Florbetapir-PET for Imaging β-Amyloid Pathology
- (2011) Christopher M. Clark JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Increased Hippocampal Default Mode Synchronization during Rest in Middle-Aged and Elderly APOE 4 Carriers: Relationships with Memory Performance
- (2011) E. T. Westlye et al. JOURNAL OF NEUROSCIENCE
- APOE and Alzheimer disease: a major gene with semi-dominant inheritance
- (2011) E Genin et al. MOLECULAR PSYCHIATRY
- Glucose metabolism and gray-matter concentration in apolipoprotein E ε4 positive normal subjects
- (2011) Miharu Samuraki et al. NEUROBIOLOGY OF AGING
- APOE modifies the association between A load and cognition in cognitively normal older adults
- (2011) K. Kantarci et al. NEUROLOGY
- Progressive regional atrophy in normal adults with a maternal history of Alzheimer disease
- (2011) R. A. Honea et al. NEUROLOGY
- Interaction effects of subjective memory impairment and ApoE4 genotype on episodic memory and hippocampal volume
- (2011) N. Striepens et al. PSYCHOLOGICAL MEDICINE
- Family History of Alzheimer's Disease and Hippocampal Structure in Healthy People
- (2010) Markus Donix et al. AMERICAN JOURNAL OF PSYCHIATRY
- Apolipoprotein E4allele in the normal elderly: neuropsychologic and brain MRI correlates
- (2010) H. Schmidt et al. CLINICAL GENETICS
- Revising the definition of Alzheimer's disease: a new lexicon
- (2010) Bruno Dubois et al. LANCET NEUROLOGY
- Longitudinal MRI atrophy biomarkers: Relationship to conversion in the ADNI cohort
- (2010) Shannon L. Risacher et al. NEUROBIOLOGY OF AGING
- Sex and age differences in atrophic rates: an ADNI study with n=1368 MRI scans
- (2010) Xue Hua et al. NEUROBIOLOGY OF AGING
- Amyloid imaging results from the Australian Imaging, Biomarkers and Lifestyle (AIBL) study of aging
- (2010) Christopher C. Rowe et al. NEUROBIOLOGY OF AGING
- The effects of APOE-ε4 on the BOLD response
- (2010) Aaron J. Trachtenberg et al. NEUROBIOLOGY OF AGING
- Longitudinal changes in medial temporal cortical thickness in normal subjects with the APOE-4 polymorphism
- (2010) Markus Donix et al. NEUROIMAGE
- Differential effects of the APOE genotype on brain function across the lifespan
- (2010) N. Filippini et al. NEUROIMAGE
- Hippocampal atrophy rates and CSF biomarkers in elderly APOE2 normal subjects
- (2010) G. C. Chiang et al. NEUROLOGY
- Reduced gray matter volume in normal adults with a maternal family history of Alzheimer disease
- (2010) R. A. Honea et al. NEUROLOGY
- Medial temporal lobe dysfunction during encoding and retrieval of episodic memory in non-demented APOE ε4 carriers
- (2010) J. Kukolja et al. NEUROSCIENCE
- Cortical thickness is associated with different apolipoprotein E genotypes in healthy elderly adults
- (2010) Ming Fan et al. NEUROSCIENCE LETTERS
- Aβ-independent roles of apolipoprotein E4 in the pathogenesis of Alzheimer's disease
- (2010) Yadong Huang TRENDS IN MOLECULAR MEDICINE
- Temporal lobe functional activity and connectivity in young adult APOE ɛ4 carriers
- (2009) Nancy A. Dennis et al. Alzheimers & Dementia
- Apolipoprotein E-dependent accumulation of Alzheimer disease-related lesions begins in middle age
- (2009) Eloise Kok et al. ANNALS OF NEUROLOGY
- APOEpredicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
- (2009) John C. Morris et al. ANNALS OF NEUROLOGY
- Cortical Binding of Pittsburgh Compound B, an Endophenotype for Genetic Studies of Alzheimer's Disease
- (2009) Anthony L. Hinrichs et al. BIOLOGICAL PSYCHIATRY
- Selective effect of age, Apo e4, and Alzheimer's disease on hippocampal subfields
- (2009) Susanne G. Mueller et al. HIPPOCAMPUS
- Apolipoprotein E and its receptors in Alzheimer's disease: pathways, pathogenesis and therapy
- (2009) Guojun Bu NATURE REVIEWS NEUROSCIENCE
- Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease
- (2009) Nanthia A. Suthana et al. NEUROIMAGE
- APOE 2 is associated with intact cognition but increased Alzheimer pathology in the oldest old
- (2009) D. J. Berlau et al. NEUROLOGY
- The Role of Apolipoprotein E in Alzheimer's Disease
- (2009) Jungsu Kim et al. NEURON
- Fibrillar amyloid- burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
- (2009) E. M. Reiman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Distinct patterns of brain activity in young carriers of the APOE- 4 allele
- (2009) N. Filippini et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Assessment of β-Amyloid in a Frontal Cortical Brain Biopsy Specimen and by Positron Emission Tomography With Carbon 11–Labeled Pittsburgh Compound B
- (2008) Ville Leinonen ARCHIVES OF NEUROLOGY
- Post-mortem correlates of in vivo PiB-PET amyloid imaging in a typical case of Alzheimer's disease
- (2008) Milos D. Ikonomovic et al. BRAIN
- Selective effect of Apo e4 on CA3 and dentate in normal aging and Alzheimer's disease using high resolution MRI at 4 T
- (2008) S.G. Mueller et al. NEUROIMAGE
- Reduced cortical thickness in hippocampal subregions among cognitively normal apolipoprotein E e4 carriers
- (2008) A.C. Burggren et al. NEUROIMAGE
- Automated mapping of hippocampal atrophy in 1-year repeat MRI data from 490 subjects with Alzheimer's disease, mild cognitive impairment, and elderly controls
- (2008) Jonathan H. Morra et al. NEUROIMAGE
- Declining brain glucose metabolism in normal individuals with a maternal history of Alzheimer disease
- (2008) L. Mosconi et al. NEUROLOGY
- Accelerated age-related cortical thinning in healthy carriers of apolipoprotein E ɛ4
- (2006) Thomas Espeseth et al. NEUROBIOLOGY OF AGING
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