Of ticks, mice and men: understanding the dual-host lifestyle of Lyme disease spirochaetes

A Critical Role for Type I IFN in Arthritis Development following Borrelia burgdorferi Infection of Mice

(2014) J. C. Miller et al.   JOURNAL OF IMMUNOLOGY

Analysis of the Borrelia burgdorferi Cyclic-di-GMP-Binding Protein PlzA Reveals a Role in Motility and Virulence

(2011) Joshua E. Pitzer et al.   INFECTION AND IMMUNITY

The OspE-Related Proteins Inhibit Complement Deposition and Enhance Serum Resistance ofBorrelia burgdorferi, the Lyme Disease Spirochete

(2011) Melisha R. Kenedy et al.   INFECTION AND IMMUNITY

Analysis of the HD-GYP Domain Cyclic Dimeric GMP Phosphodiesterase Reveals a Role in Motility and the Enzootic Life Cycle of Borrelia burgdorferi

(2011) Syed Z. Sultan et al.   INFECTION AND IMMUNITY

The Hybrid Histidine Kinase Hk1 Is Part of a Two-Component System That Is Essential for Survival of Borrelia burgdorferi in Feeding Ixodes scapularis Ticks

(2011) Melissa J. Caimano et al.   INFECTION AND IMMUNITY

Chemoreceptors and Flagellar Motors Are Subterminally Located in Close Proximity at the Two Cell Poles in Spirochetes

(2011) H. Xu et al.   JOURNAL OF BACTERIOLOGY

The coenzyme A disulphide reductase of Borrelia burgdorferi is important for rapid growth throughout the enzootic cycle and essential for infection of the mammalian host

(2011) Christian H. Eggers et al.   MOLECULAR MICROBIOLOGY

The diguanylate cyclase, Rrp1, regulates critical steps in the enzootic cycle of the Lyme disease spirochetes

(2011) Jessica L. Kostick et al.   MOLECULAR MICROBIOLOGY

Nod2 Suppresses Borrelia burgdorferi Mediated Murine Lyme Arthritis and Carditis through the Induction of Tolerance

(2011) Tanja Petnicki-Ocwieja et al.   PLoS One

HrpA, a DEAH-Box RNA Helicase, Is Involved in Global Gene Regulation in the Lyme Disease Spirochete

(2011) Aydan Salman-Dilgimen et al.   PLoS One

Phagosomal signaling byBorrelia burgdorferiin human monocytes involves Toll-like receptor (TLR) 2 and TLR8 cooperativity and TLR8-mediated induction of IFN-β

(2011) Jorge L. Cervantes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BosR (BB0647) Controls the RpoN-RpoS Regulatory Pathway and Virulence Expression in Borrelia burgdorferi by a Novel DNA-Binding Mechanism

(2011) Zhiming Ouyang et al.   PLoS Pathogens

Borrelia burgdorferi Requires Glycerol for Maximum Fitness During The Tick Phase of the Enzootic Cycle

(2011) Christopher J. Pappas et al.   PLoS Pathogens

Molecular Interactions that Enable Movement of the Lyme Disease Agent from the Tick Gut into the Hemolymph

(2011) Lili Zhang et al.   PLoS Pathogens

Lymphoadenopathy during Lyme Borreliosis Is Caused by Spirochete Migration-Induced Specific B Cell Activation

(2011) Stefan S. Tunev et al.   PLoS Pathogens

Cyclic di-GMP is Essential for the Survival of the Lyme Disease Spirochete in Ticks

(2011) Ming He et al.   PLoS Pathogens

Gene Regulation inBorrelia burgdorferi

(2010) D. Scott Samuels   Annual Review of Microbiology

Cholesterol Lipids of Borrelia burgdorferi Form Lipid Rafts and Are Required for the Bactericidal Activity of a Complement-Independent Antibody

(2010) Timothy J. LaRocca et al.   Cell Host & Microbe

CsrA Modulates Levels of Lipoproteins and Key Regulators of Gene Expression Critical for Pathogenic Mechanisms ofBorrelia burgdorferi

(2010) S. L. Rajasekhar Karna et al.   INFECTION AND IMMUNITY

Inactivation ofbb0184, Which Encodes Carbon Storage Regulator A, Represses the Infectivity ofBorrelia burgdorferi

(2010) Ching Wooen Sze et al.   INFECTION AND IMMUNITY

BBA52 FacilitatesBorrelia burgdorferiTransmission from Feeding Ticks to Murine Hosts

(2010) Manish Kumar et al.   JOURNAL OF INFECTIOUS DISEASES

Identification and function of the RNA chaperone Hfq in the Lyme disease spirochete Borrelia burgdorferi

(2010) Meghan C. Lybecker et al.   MOLECULAR MICROBIOLOGY

Analysis of a Borrelia burgdorferi phosphodiesterase demonstrates a role for cyclic-di-guanosine monophosphate in motility and virulence

(2010) Syed Z. Sultan et al.   MOLECULAR MICROBIOLOGY

An intravascular immune response to Borrelia burgdorferi involves Kupffer cells and iNKT cells

(2010) Woo-Yong Lee et al.   NATURE IMMUNOLOGY

Human Integrin α3β1 Regulates TLR2 Recognition of Lipopeptides from Endosomal Compartments

(2010) Meghan L. Marre et al.   PLoS One

Complement Factor H-Related Proteins CFHR2 and CFHR5 Represent Novel Ligands for the Infection-Associated CRASP Proteins of Borrelia burgdorferi

(2010) Corinna Siegel et al.   PLoS One

The bba64 gene of Borrelia burgdorferi, the Lyme disease agent, is critical for mammalian infection via tick bite transmission

(2010) R. D. Gilmore et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lyme Borreliosis in Dogs and Cats: Background, Diagnosis, Treatment and Prevention of Infections with Borrelia burgdorferi sensu stricto

(2010) Inke Krupka et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Role of Acetyl-Phosphate in Activation of the Rrp2-RpoN-RpoS Pathway in Borrelia burgdorferi

(2010) Haijun Xu et al.   PLoS Pathogens

Identification and molecular characterization of a cyclic-di-GMP effector protein, PlzA (BB0733): additional evidence for the existence of a functional cyclic-di-GMP regulatory network in the Lyme disease spirochete,Borrelia burgdorferi

(2009) John C. Freedman et al.   FEMS IMMUNOLOGY AND MEDICAL MICROBIOLOGY

Inhibition of Neutrophil Function by Two Tick Salivary Proteins

(2009) X. Guo et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi RevA Antigen Binds Host Fibronectin

(2009) C. A. Brissette et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi BmpA Is a Laminin-Binding Protein

(2009) A. Verma et al.   INFECTION AND IMMUNITY

Borrelia burgdorferi bba74 Is Expressed Exclusively during Tick Feeding and Is Regulated by Both Arthropod- and Mammalian Host-Specific Signals

(2009) V. B. Mulay et al.   JOURNAL OF BACTERIOLOGY

GuaA and GuaB Are Essential for Borrelia burgdorferi Survival in the Tick-Mouse Infection Cycle

(2009) M. W. Jewett et al.   JOURNAL OF BACTERIOLOGY

Rrp2, a  54-Dependent Transcriptional Activator of Borrelia burgdorferi, Activates rpoS in an Enhancer-Independent Manner

(2009) J. S. Blevins et al.   JOURNAL OF BACTERIOLOGY

Intact Flagellar Motor of Borrelia burgdorferi Revealed by Cryo-Electron Tomography: Evidence for Stator Ring Curvature and Rotor/C-Ring Assembly Flexion

(2009) J. Liu et al.   JOURNAL OF BACTERIOLOGY

Live imaging reveals a biphasic mode of dissemination of Borrelia burgdorferi within ticks

(2009) Star M. Dunham-Ems et al.   JOURNAL OF CLINICAL INVESTIGATION

Local Production of IFN-  by Invariant NKT Cells Modulates Acute Lyme Carditis

(2009) C. M. Olson et al.   JOURNAL OF IMMUNOLOGY

Recognition of Borrelia burgdorferi, the Lyme Disease Spirochete, by TLR7 and TLR9 Induces a Type I IFN Response by Human Immune Cells

(2009) M. M. Petzke et al.   JOURNAL OF IMMUNOLOGY

The Borrelia burgdorferi outer-surface protein ErpX binds mammalian laminin

(2009) C. A. Brissette et al.   MICROBIOLOGY-SGM

The BosR regulatory protein of Borrelia burgdorferi interfaces with the RpoS regulatory pathway and modulates both the oxidative stress response and pathogenic properties of the Lyme disease spirochete

(2009) Jenny A. Hyde et al.   MOLECULAR MICROBIOLOGY

Borrelia burgdorferilocus BB0795 encodes a BamA orthologue required for growth and efficient localization of outer membrane proteins

(2009) Tiffany R. Lenhart et al.   MOLECULAR MICROBIOLOGY

Rrp1, a cyclic-di-GMP-producing response regulator, is an important regulator ofBorrelia burgdorfericore cellular functions

(2009) Elizabeth A. Rogers et al.   MOLECULAR MICROBIOLOGY

Borrelia burgdorferismall lipoprotein Lp6.6 is a member of multiple protein complexes in the outer membrane and facilitates pathogen transmission from ticks to mice

(2009) Kamoltip Promnares et al.   MOLECULAR MICROBIOLOGY

Interaction of Borrelia burgdorferi Hbb with the p66 promoter

(2009) M. S. Medrano et al.   NUCLEIC ACIDS RESEARCH

Assessment of decorin-binding protein A to the infectivity of Borrelia burgdorferi in the murine models of needle and tick infection

(2008) Jon S Blevins et al.   BMC MICROBIOLOGY

Borrelia burgdorferi Infection-Associated Surface Proteins ErpP, ErpA, and ErpC Bind Human Plasminogen

(2008) C. A. Brissette et al.   INFECTION AND IMMUNITY

Distinct Roles for MyD88 and Toll-Like Receptors 2, 5, and 9 in Phagocytosis of Borrelia burgdorferi and Cytokine Induction

(2008) O. S. Shin et al.   INFECTION AND IMMUNITY

Both Decorin-Binding Proteins A and B Are Critical for the Overall Virulence of Borrelia burgdorferi

(2008) Y. Shi et al.   INFECTION AND IMMUNITY

Outer Surface Protein A Protects Lyme Disease Spirochetes from Acquired Host Immunity in the Tick Vector

(2008) J. M. Battisti et al.   INFECTION AND IMMUNITY

Essential Role of the Response Regulator Rrp2 in the Infectious Cycle of Borrelia burgdorferi

(2008) B. K. Boardman et al.   INFECTION AND IMMUNITY

Lyme Disease—European Perspective

(2008) Gerold Stanek et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

The Flat-Ribbon Configuration of the Periplasmic Flagella of Borrelia burgdorferi and Its Relationship to Motility and Morphology

(2008) N. W. Charon et al.   JOURNAL OF BACTERIOLOGY

Borrelia burgdorferiGenotype Predicts the Capacity for Hematogenous Dissemination during Early Lyme Disease

(2008) Gary P. Wormser et al.   JOURNAL OF INFECTIOUS DISEASES

An RND-Type Efflux System in Borrelia burgdorferi Is Involved in Virulence and Resistance to Antimicrobial Compounds

(2008) Ignas Bunikis et al.   PLoS Pathogens

Real-Time High Resolution 3D Imaging of the Lyme Disease Spirochete Adhering to and Escaping from the Vasculature of a Living Host

(2008) Tara J. Moriarty et al.   PLoS Pathogens

Higher mRNA Levels of Chemokines and Cytokines Associated with Macrophage Activation in Erythema Migrans Skin Lesions in Patients from the United States than in Patients from Austria with Lyme Borreliosis

(2007) K. L. Jones et al.   CLINICAL INFECTIOUS DISEASES

A Differential Role for BB0365 in the Persistence ofBorrelia burgdorferiin Mice and Ticks

(2007) Utpal Pal et al.   JOURNAL OF INFECTIOUS DISEASES