The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration
出版年份 2018 全文链接
标题
The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration
作者
关键词
-
出版物
Nature Reviews Cardiology
Volume -, Issue -, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-08-16
DOI
10.1038/s41569-018-0063-3
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- YAP/TAZ-Dependent Reprogramming of Colonic Epithelium Links ECM Remodeling to Tissue Regeneration
- (2018) Shiro Yui et al. Cell Stem Cell
- α-Catenin-dependent cytoskeletal tension controls Yap activity in the heart
- (2018) Alexia Vite et al. DEVELOPMENT
- Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development
- (2018) Yang Xiao et al. DEVELOPMENTAL CELL
- The epicardium as a hub for heart regeneration
- (2018) Jingli Cao et al. Nature Reviews Cardiology
- YAP repression of theWNT3gene controls hESC differentiation along the cardiac mesoderm lineage
- (2017) Conchi Estarás et al. GENES & DEVELOPMENT
- Epicardial YAP/TAZ orchestrate an immunosuppressive response following myocardial infarction
- (2017) Vimal Ramjee et al. JOURNAL OF CLINICAL INVESTIGATION
- Hippo Pathway: An Emerging Regulator of Craniofacial and Dental Development
- (2017) J. Wang et al. JOURNAL OF DENTAL RESEARCH
- Hippo pathway deficiency reverses systolic heart failure after infarction
- (2017) John P. Leach et al. NATURE
- Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation
- (2017) Yuka Morikawa et al. NATURE
- The extracellular matrix protein agrin promotes heart regeneration in mice
- (2017) Elad Bassat et al. NATURE
- Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest
- (2017) Richard J. Mills et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Amotl1 mediates sequestration of the Hippo effector Yap1 downstream of Fat4 to restrict heart growth
- (2017) Chiara V. Ragni et al. Nature Communications
- VGLL4 targets a TCF4–TEAD4 complex to coregulate Wnt and Hippo signalling in colorectal cancer
- (2017) Shi Jiao et al. Nature Communications
- YAP/TAZ at the Roots of Cancer
- (2016) Francesca Zanconato et al. CANCER CELL
- Opposing Roles of Wnt Inhibitors IGFBP-4 and Dkk1 in Cardiac Ischemia by Differential Targeting of LRP5/6 and β-cateninClinical Perspective
- (2016) Da Wo et al. CIRCULATION
- Regulation of Myocardial Cell Growth and Death by the Hippo Pathway
- (2016) Shohei Ikeda et al. CIRCULATION JOURNAL
- NF2 Activates Hippo Signaling and Promotes Ischemia/Reperfusion Injury in the HeartNovelty and Significance
- (2016) Takahisa Matsuda et al. CIRCULATION RESEARCH
- Acetylation of VGLL4 Regulates Hippo-YAP Signaling and Postnatal Cardiac Growth
- (2016) Zhiqiang Lin et al. DEVELOPMENTAL CELL
- Pitx2 promotes heart repair by activating the antioxidant response after cardiac injury
- (2016) Ge Tao et al. NATURE
- Hippo Signaling Mediators Yap and Taz Are Required in the Epicardium for Coronary Vasculature Development
- (2016) Anamika Singh et al. Cell Reports
- ERG Activates the YAP1 Transcriptional Program and Induces the Development of Age-Related Prostate Tumors
- (2015) Liem T. Nguyen et al. CANCER CELL
- miR-206 Mediates YAP-Induced Cardiac Hypertrophy and SurvivalNovelty and Significance
- (2015) Yanfei Yang et al. CIRCULATION RESEARCH
- Distinct Polarity Cues Direct Taz/Yap and TGFβ Receptor Localization to Differentially Control TGFβ-Induced Smad Signaling
- (2015) Masahiro Narimatsu et al. DEVELOPMENTAL CELL
- Dynamic changes in the cardiac methylome during postnatal development
- (2015) Choon Boon Sim et al. FASEB JOURNAL
- A YAP/TAZ-induced feedback mechanism regulates Hippo pathway homeostasis
- (2015) Toshiro Moroishi et al. GENES & DEVELOPMENT
- Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63Transcription through TEA Domain (TEAD) Transcription Factor
- (2015) Ivette Valencia-Sama et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Yap-dependent reprogramming of Lgr5+ stem cells drives intestinal regeneration and cancer
- (2015) Alex Gregorieff et al. NATURE
- A gp130–Src–YAP module links inflammation to epithelial regeneration
- (2015) Koji Taniguchi et al. NATURE
- ERBB2 triggers mammalian heart regeneration by promoting cardiomyocyte dedifferentiation and proliferation
- (2015) Gabriele D’Uva et al. NATURE CELL BIOLOGY
- Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction
- (2015) Anne-Laure Leblond et al. PLoS One
- Deregulation of the Hippo pathway in soft-tissue sarcoma promotes FOXM1 expression and tumorigenesis
- (2015) T. S. Karin Eisinger-Mathason et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
- (2015) Yuka Morikawa et al. Science Signaling
- A microRNA-Hippo pathway that promotes cardiomyocyte proliferation and cardiac regeneration in mice
- (2015) Ying Tian et al. Science Translational Medicine
- Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice
- (2015) Yuka Morikawa et al. Science Signaling
- Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure
- (2014) Diogo Mosqueira et al. ACS Nano
- The alteration of Hippo/YAP signaling in the development of hypertrophic cardiomyopathy
- (2014) Pei Wang et al. BASIC RESEARCH IN CARDIOLOGY
- A Peptide Mimicking VGLL4 Function Acts as a YAP Antagonist Therapy against Gastric Cancer
- (2014) Shi Jiao et al. CANCER CELL
- The Oxygen-Rich Postnatal Environment Induces Cardiomyocyte Cell-Cycle Arrest through DNA Damage Response
- (2014) Bao N. Puente et al. CELL
- YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response
- (2014) Luca Azzolin et al. CELL
- VGLL4 functions as a new tumor suppressor in lung cancer by negatively regulating the YAP-TEAD transcriptional complex
- (2014) Wenjing Zhang et al. CELL RESEARCH
- Cardiac-Specific YAP Activation Improves Cardiac Function and Survival in an Experimental Murine MI Model
- (2014) Zhiqiang Lin et al. CIRCULATION RESEARCH
- Macro advances in microRNAs and myocardial regeneration
- (2014) Jun Wang et al. CURRENT OPINION IN CARDIOLOGY
- How to make a cardiomyocyte
- (2014) D. Spater et al. DEVELOPMENT
- The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
- (2014) X. Varelas DEVELOPMENT
- Curcumin Promotes KLF5 Proteasome Degradation through Downregulating YAP/TAZ in Bladder Cancer Cells
- (2014) Yang Gao et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Macrophages are required for neonatal heart regeneration
- (2014) Arin B. Aurora et al. JOURNAL OF CLINICAL INVESTIGATION
- Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
- (2014) Biao Ma et al. NATURE CELL BIOLOGY
- Early lineage restriction in temporally distinct populations of Mesp1 progenitors during mammalian heart development
- (2014) Fabienne Lescroart et al. NATURE CELL BIOLOGY
- Downstream of Mutant KRAS, the Transcription Regulator YAP Is Essential for Neoplastic Progression to Pancreatic Ductal Adenocarcinoma
- (2014) W. Zhang et al. Science Signaling
- Pax3 and Hippo Signaling Coordinate Melanocyte Gene Expression in Neural Crest
- (2014) Lauren J. Manderfield et al. Cell Reports
- The Yes-associated protein controls the cell density regulation of Hedgehog signaling
- (2014) M Tariki et al. Oncogenesis
- A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
- (2013) Mariaceleste Aragona et al. CELL
- The Hippo Pathway Is Activated and Is a Causal Mechanism for Adipogenesis in Arrhythmogenic Cardiomyopathy
- (2013) Suet Nee Chen et al. CIRCULATION RESEARCH
- Hippo signaling impedes adult heart regeneration
- (2013) T. Heallen et al. DEVELOPMENT
- Fibronectin is deposited by injury-activated epicardial cells and is necessary for zebrafish heart regeneration
- (2013) Jinhu Wang et al. DEVELOPMENTAL BIOLOGY
- Hypoxia inducible factor-1 is activated by transcriptional co-activator with PDZ-binding motif (TAZ) versus WWdomain-containing oxidoreductase (WWOX) in hypoxic microenvironment of bone metastasis from breast cancer
- (2013) Paola Bendinelli et al. EUROPEAN JOURNAL OF CANCER
- The Hippo pathway: regulators and regulations
- (2013) F.-X. Yu et al. GENES & DEVELOPMENT
- TRIB2 Acts Downstream of Wnt/TCF in Liver Cancer Cells to Regulate YAP and C/EBPα Function
- (2013) Jiayi Wang et al. MOLECULAR CELL
- Mst1 inhibits autophagy by promoting the interaction between Beclin1 and Bcl-2
- (2013) Yasuhiro Maejima et al. NATURE MEDICINE
- Hippo pathway effector Yap promotes cardiac regeneration
- (2013) Mei Xin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells
- (2013) Tobias A. Beyer et al. Cell Reports
- YAP Promotes Breast Cell Proliferation and Survival Partially through Stabilizing the KLF5 Transcription Factor
- (2012) Xu Zhi et al. AMERICAN JOURNAL OF PATHOLOGY
- β-Catenin-Driven Cancers Require a YAP1 Transcriptional Complex for Survival and Tumorigenesis
- (2012) Joseph Rosenbluh et al. CELL
- Role of TAZ as Mediator of Wnt Signaling
- (2012) Luca Azzolin et al. CELL
- The Fire Within: Cardiac Inflammatory Signaling in Health and Disease
- (2012) Matthew Coggins et al. CIRCULATION RESEARCH
- The bHLH transcription factor Tcf21 is required for lineage-specific EMT of cardiac fibroblast progenitors
- (2012) A. Acharya et al. DEVELOPMENT
- Distinct Compartments of the Proepicardial Organ Give Rise to Coronary Vascular Endothelial Cells
- (2012) Tamar C. Katz et al. DEVELOPMENTAL CELL
- A molecular mechanism that links Hippo signalling to the inhibition of Wnt/β-catenin signalling
- (2012) Masamichi Imajo et al. EMBO JOURNAL
- Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis
- (2012) B. Zhao et al. GENES & DEVELOPMENT
- Hepatitis B virus X protein modulates oncogene yes-associated protein by CREB to promote growth of hepatoma cells
- (2012) Tao Zhang et al. HEPATOLOGY
- Yes-associated Protein Isoform 1 (Yap1) Promotes Cardiomyocyte Survival and Growth to Protect against Myocardial Ischemic Injury
- (2012) Dominic P. Del Re et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TGF-β synergizes with defects in the Hippo pathway to stimulate human malignant mesothelioma growth
- (2012) Makiko Fujii et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Restriction of intestinal stem cell expansion and the regenerative response by YAP
- (2012) Evan R. Barry et al. NATURE
- YAP mediates crosstalk between the Hippo and PI(3)K–TOR pathways by suppressing PTEN via miR-29
- (2012) Karen Tumaneng et al. NATURE CELL BIOLOGY
- Transduction of mechanical and cytoskeletal cues by YAP and TAZ
- (2012) Georg Halder et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cardiac Regeneration from Activated Epicardium
- (2012) Bram van Wijk et al. PLoS One
- YAP1, the nuclear target of Hippo signaling, stimulates heart growth through cardiomyocyte proliferation but not hypertrophy
- (2012) A. von Gise et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family
- (2012) E. R. Porrello et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- C/EBP Transcription Factors Mediate Epicardial Activation During Heart Development and Injury
- (2012) G. N. Huang et al. SCIENCE
- Molecular determinants of cardiac specification
- (2011) C. Lopez-Sanchez et al. CARDIOVASCULAR RESEARCH
- Yap1 Acts Downstream of α-Catenin to Control Epidermal Proliferation
- (2011) Karin Schlegelmilch et al. CELL
- Yes-associated protein 1 regulates the stability of ΔNp63α
- (2011) Aditi Chatterjee et al. CELL CYCLE
- Actin-Capping Protein and the Hippo pathway regulate F-actin and tissue growth in Drosophila
- (2011) B. G. Fernandez et al. DEVELOPMENT
- Hippo pathway regulation by cell morphology and stress fibers
- (2011) K.-I. Wada et al. DEVELOPMENT
- Modulating F-actin organization induces organ growth by affecting the Hippo pathway
- (2011) Leticia Sansores-Garcia et al. EMBO JOURNAL
- Role of YAP/TAZ in mechanotransduction
- (2011) Sirio Dupont et al. NATURE
- De novo cardiomyocytes from within the activated adult heart after injury
- (2011) Nicola Smart et al. NATURE
- Hippo Pathway Inhibits Wnt Signaling to Restrain Cardiomyocyte Proliferation and Heart Size
- (2011) T. Heallen et al. SCIENCE
- Transient Regenerative Potential of the Neonatal Mouse Heart
- (2011) E. R. Porrello et al. SCIENCE
- Executive Summary: Heart Disease and Stroke Statistics—2010 Update
- (2010) et al. CIRCULATION
- The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals
- (2010) Nailing Zhang et al. DEVELOPMENTAL CELL
- The Hippo Pathway Regulates Wnt/β-Catenin Signaling
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- The Hippo Signaling Pathway in Development and Cancer
- (2010) Duojia Pan DEVELOPMENTAL CELL
- The Crumbs Complex Couples Cell Density Sensing to Hippo-Dependent Control of the TGF-β-SMAD Pathway
- (2010) Xaralabos Varelas et al. DEVELOPMENTAL CELL
- TAZ as a novel enhancer of MyoD-mediated myogenic differentiation
- (2010) Hana Jeong et al. FASEB JOURNAL
- TEAD-1 Overexpression in the Mouse Heart Promotes an Age-dependent Heart Dysfunction
- (2010) Richard W. Tsika et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Energy Metabolic Phenotype of the Cardiomyocyte During Development, Differentiation, and Postnatal Maturation
- (2010) Gary D Lopaschuk et al. JOURNAL OF CARDIOVASCULAR PHARMACOLOGY
- Proapoptotic Rassf1A/Mst1 signaling in cardiac fibroblasts is protective against pressure overload in mice
- (2010) Dominic P. Del Re et al. JOURNAL OF CLINICAL INVESTIGATION
- Primary contribution to zebrafish heart regeneration by gata4 + cardiomyocytes
- (2010) Kazu Kikuchi et al. NATURE
- Zebrafish heart regeneration occurs by cardiomyocyte dedifferentiation and proliferation
- (2010) Chris Jopling et al. NATURE
- Both TEAD-Binding and WW Domains Are Required for the Growth Stimulation and Oncogenic Transformation Activity of Yes-Associated Protein
- (2009) B. Zhao et al. CANCER RESEARCH
- Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways
- (2009) Claudio Alarcón et al. CELL
- Tumor Suppressor Ras-Association Domain Family 1 Isoform A Is a Novel Regulator of Cardiac Hypertrophy
- (2009) Delvac Oceandy et al. CIRCULATION
- Heart Disease and Stroke Statistics—2010 Update
- (2009) et al. CIRCULATION
- TEAD Transcription Factors Mediate the Function of TAZ in Cell Growth and Epithelial-Mesenchymal Transition
- (2009) Heng Zhang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MST Kinases Monitor Actin Cytoskeletal Integrity and Signal via c-Jun N-Terminal Kinase Stress-Activated Kinase To Regulate p21Waf1/Cip1 Stability
- (2009) R. M. Densham et al. MOLECULAR AND CELLULAR BIOLOGY
- EGR-1 forms a complex with YAP-1 and upregulates Bax expression in irradiated prostate carcinoma cells
- (2009) M Zagurovskaya et al. ONCOGENE
- Evidence for Cardiomyocyte Renewal in Humans
- (2009) Olaf Bergmann et al. SCIENCE
- Human angiomotin-like 1 associates with an angiomotin protein complex through its coiled-coil domain and induces the remodeling of the actin cytoskeleton
- (2009) Valérie Gagné et al. CELL MOTILITY AND THE CYTOSKELETON
- Lats2 Is a Negative Regulator of Myocyte Size in the Heart
- (2008) Yutaka Matsui et al. CIRCULATION RESEARCH
- The Hippo–YAP pathway: new connections between regulation of organ size and cancer
- (2008) Bin Zhao et al. CURRENT OPINION IN CELL BIOLOGY
- Wnt3a-mediated chemorepulsion controls movement patterns of cardiac progenitors and requires RhoA function
- (2008) Q. Yue et al. DEVELOPMENT
- A New Kid on the TGFβ Block: TAZ Controls Smad Nucleocytoplasmic Shuttling
- (2008) Katharine H. Wrighton et al. DEVELOPMENTAL CELL
- TEAD mediates YAP-dependent gene induction and growth control
- (2008) B. Zhao et al. GENES & DEVELOPMENT
- Yap1 Phosphorylation by c-Abl Is a Critical Step in Selective Activation of Proapoptotic Genes in Response to DNA Damage
- (2008) Dan Levy et al. MOLECULAR CELL
- PML, YAP, and p73 Are Components of a Proapoptotic Autoregulatory Feedback Loop
- (2008) Eleonora Lapi et al. MOLECULAR CELL
- TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal
- (2008) Xaralabos Varelas et al. NATURE CELL BIOLOGY
- Mechanisms Underlying Acute Protection From Cardiac Ischemia-Reperfusion Injury
- (2008) Elizabeth Murphy et al. PHYSIOLOGICAL REVIEWS
- -Catenin downregulation attenuates ischemic cardiac remodeling through enhanced resident precursor cell differentiation
- (2008) L. C. Zelarayan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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