标题
Small-molecule proteostasis regulators for protein conformational diseases
作者
关键词
-
出版物
Nature Chemical Biology
Volume 8, Issue 2, Pages 185-196
出版商
Springer Nature
发表日期
2011-12-26
DOI
10.1038/nchembio.763
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Improved Small-Molecule Macroarray Platform for the Rapid Synthesis and Discovery of Antibacterial Chalcones
- (2011) Joseph R. Stringer et al. ACS Combinatorial Science
- A cellular perspective on conformational disease: the role of genetic background and proteostasis networks
- (2010) Tali Gidalevitz et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- Prevention of autosomal dominant retinitis pigmentosa by systemic drug therapy targeting heat shock protein 90 (Hsp90)
- (2010) Lawrence C.S. Tam et al. HUMAN MOLECULAR GENETICS
- The role of chalcones in suppression of NF-κB-mediated inflammation and cancer
- (2010) Vivek R. Yadav et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- The mitochondrial UPR - protecting organelle protein homeostasis
- (2010) C. M. Haynes et al. JOURNAL OF CELL SCIENCE
- Microglia in the aging brain: relevance to neurodegeneration
- (2010) Xiao-Guang Luo et al. Molecular Neurodegeneration
- Heat shock factors: integrators of cell stress, development and lifespan
- (2010) Malin Åkerfelt et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Restoration of visual function in P23H rhodopsin transgenic rats by gene delivery of BiP/Grp78
- (2010) M. S. Gorbatyuk et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modulation of Heat Shock Transcription Factor 1 as a Therapeutic Target for Small Molecule Intervention in Neurodegenerative Disease
- (2010) Daniel W. Neef et al. PLOS BIOLOGY
- Biological and Chemical Approaches to Diseases of Proteostasis Deficiency
- (2009) Evan T. Powers et al. Annual Review of Biochemistry
- Induction of heat shock response by curcumin in human leukemia cells
- (2009) Marie-Hélène Teiten et al. CANCER LETTERS
- Treating lysosomal storage diseases with pharmacological chaperones: from concept to clinics
- (2009) Giancarlo Parenti EMBO Molecular Medicine
- The Nrf2–ARE cytoprotective pathway in astrocytes
- (2009) Marcelo R. Vargas et al. EXPERT REVIEWS IN MOLECULAR MEDICINE
- CFTR Function and Prospects for Therapy
- (2008) John R. Riordan Annual Review of Biochemistry
- Chemical and Biological Approaches Synergize to Ameliorate Protein-Folding Diseases
- (2008) Ting-Wei Mu et al. CELL
- Phase II Trial of 17-Allylamino-17-Demethoxygeldanamycin in Patients with Metastatic Melanoma
- (2008) D. B. Solit et al. CLINICAL CANCER RESEARCH
- Targeting Hsp90: small-molecule inhibitors and their clinical development
- (2008) Tony Taldone et al. CURRENT OPINION IN PHARMACOLOGY
- Heat shock response relieves ER stress
- (2008) Yu Liu et al. EMBO JOURNAL
- Proteotoxic stress and inducible chaperone networks in neurodegenerative disease and aging
- (2008) R. I. Morimoto GENES & DEVELOPMENT
- Heat Shock Transcription Factor 1-activating Compounds Suppress Polyglutamine-induced Neurodegeneration through Induction of Multiple Molecular Chaperones
- (2008) Nobuhiro Fujikake et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Thiopental Protects Human T Lymphocytes from Apoptosis in Vitro via the Expression of Heat Shock Protein 70
- (2008) M. Roesslein et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Activation of Heat Shock and Antioxidant Responses by the Natural Product Celastrol: Transcriptional Signatures of a Thiol-targeted Molecule
- (2008) Amy Trott et al. MOLECULAR BIOLOGY OF THE CELL
- Adapting Proteostasis for Disease Intervention
- (2008) William E. Balch et al. SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation