A tension-mediated glycocalyx–integrin feedback loop promotes mesenchymal-like glioblastoma

Tissue mechanics regulate brain development, homeostasis and disease

(2017) J. Matthew Barnes et al.   JOURNAL OF CELL SCIENCE

Hydroxylamine Chemical Digestion for Insoluble Extracellular Matrix Characterization

(2017) Alexander S. Barrett et al.   JOURNAL OF PROTEOME RESEARCH

Integrin-mediated traction force enhances paxillin molecular associations and adhesion dynamics that increase the invasiveness of tumor cells into a three-dimensional extracellular matrix

(2017) Armen H. Mekhdjian et al.   MOLECULAR BIOLOGY OF THE CELL

Inhibition of FAK kinase activity preferentially targets cancer stem cells

(2017) Vihren N. Kolev et al.   Oncotarget

A bulky glycocalyx fosters metastasis formation by promoting G1 cell cycle progression

(2017) Elliot C Woods et al.   eLife

The 2016 World Health Organization Classification of Tumors of the Central Nervous System: a summary

(2016) David N. Louis et al.   ACTA NEUROPATHOLOGICA

Hypoxia induces TWIST-activated epithelial–mesenchymal transition and proliferation of pancreatic cancer cells in vitro and in nude mice

(2016) Shi Chen et al.   CANCER LETTERS

Phase Ib Study of PEGylated Recombinant Human Hyaluronidase and Gemcitabine in Patients with Advanced Pancreatic Cancer

(2016) S. R. Hingorani et al.   CLINICAL CANCER RESEARCH

Glycans define the stemness of naïve and primed pluripotent stem cells

(2016) Shoko Nishihara   GLYCOCONJUGATE JOURNAL

Protein Analysis of Glioblastoma Primary and Posttreatment Pairs Suggests a Mesenchymal Shift at Recurrence

(2016) Matthew D. Wood et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Monitoring developmental force distributions in reconstituted embryonic epithelia

(2016) L. Przybyla et al.   METHODS

Tissue mechanics promote IDH1-dependent HIF1α–tenascin C feedback to regulate glioblastoma aggression

(2016) Yekaterina A. Miroshnikova et al.   NATURE CELL BIOLOGY

Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression

(2016) Hanane Laklai et al.   NATURE MEDICINE

Nuclear repartitioning of galectin-1 by an extracellular glycan switch regulates mammary morphogenesis

(2016) Ramray Bhat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Concise Review: Cell SurfaceN-Linked Glycoproteins as Potential Stem Cell Markers and Drug Targets

(2016) Kenneth R. Boheler et al.   Stem Cells Translational Medicine

Glycocalyx Engineering with a Recycling Glycopolymer that Increases Cell Survival In Vivo

(2015) Elliot C. Woods et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Epithelial-to-mesenchymal transition in paired human primary and recurrent glioblastomas

(2015) CAROLIN KUBELT et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Comprehensive Glycomics of a Multistep Human Brain Tumor Model Reveals Specific Glycosylation Patterns Related to Malignancy

(2015) Jun-ichi Furukawa et al.   PLoS One

Recurrent Glioblastomas Reveal Molecular Subtypes Associated with Mechanistic Implications of Drug-Resistance

(2015) So Mee Kwon et al.   PLoS One

MUC1 Enhances Tumor Progression and Contributes Toward Immunosuppression in a Mouse Model of Spontaneous Pancreatic Adenocarcinoma

(2014) T. L. Tinder et al.   JOURNAL OF IMMUNOLOGY

CD44-Mediated Adhesion to Hyaluronic Acid Contributes to Mechanosensing and Invasive Motility

(2014) Yushan Kim et al.   MOLECULAR CANCER RESEARCH

The cancer glycocalyx mechanically primes integrin-mediated growth and survival

(2014) Matthew J. Paszek et al.   NATURE

Identification of Novel Tumor-Associated Cell Surface Sialoglycoproteins in Human Glioblastoma Tumors Using Quantitative Proteomics

(2014) François Autelitano et al.   PLoS One

Proteoglycans and their roles in brain cancer

(2013) Anna Wade et al.   FEBS Journal

MUC1 and metastatic cancer

(2013) Teresa M. Horm et al.   Cell Adhesion & Migration

VEGF Inhibits Tumor Cell Invasion and Mesenchymal Transition through a MET/VEGFR2 Complex

(2012) Kan V. Lu et al.   CANCER CELL

Investigating Cell Surface Galectin-Mediated Cross-Linking on Glycoengineered Cells

(2012) Brian Belardi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

A restricted cell population propagates glioblastoma growth after chemotherapy

(2012) Jian Chen et al.   NATURE

Scanning angle interference microscopy reveals cell dynamics at the nanoscale

(2012) Matthew J Paszek et al.   NATURE METHODS

Efficient TGFβ-induced epithelial–mesenchymal transition depends on hyaluronan synthase HAS2

(2012) H Porsch et al.   ONCOGENE

CD44 in human glioma correlates with histopathological grade and cell migration

(2012) Tsuneyasu Yoshida et al.   PATHOLOGY INTERNATIONAL

Increased Microglia/Macrophage Gene Expression in a Subset of Adult and Pediatric Astrocytomas

(2012) Jane R. Engler et al.   PLoS One

Spatial organization of the extracellular matrix regulates cell-cell junction positioning

(2012) Q. Tseng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Hippo Transducer TAZ Confers Cancer Stem Cell-Related Traits on Breast Cancer Cells

(2011) Michelangelo Cordenonsi et al.   CELL

Differential profiling studies of N-linked glycoproteins in glioblastoma cancer stem cells upon treatment with γ-secretase inhibitor

(2011) Lan Dai et al.   PROTEOMICS

Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

(2010) Roel G.W. Verhaak et al.   CANCER CELL

Identification of Cell Surface Glycoprotein Markers for Glioblastoma-Derived Stem-Like Cells Using a Lectin Microarray and LC−MS/MS Approach

(2010) Jintang He et al.   JOURNAL OF PROTEOME RESEARCH

Enzymatic Depletion of Tumor Hyaluronan Induces Antitumor Responses in Preclinical Animal Models

(2010) C. B. Thompson et al.   MOLECULAR CANCER THERAPEUTICS

MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition

(2010) L D Roy et al.   ONCOGENE

Galectins and Gliomas

(2009) Marie Le Mercier et al.   BRAIN PATHOLOGY

Autocrine TGF-β Signaling Maintains Tumorigenicity of Glioma-Initiating Cells through Sry-Related HMG-Box Factors

(2009) Hiroaki Ikushima et al.   Cell Stem Cell

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Podoplanin, a novel marker of tumor-initiating cells in human squamous cell carcinoma A431

(2008) Naho Atsumi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts

(2008) Gaspar J. Kitange et al.   NEURO-ONCOLOGY

Evidence of galectin-1 involvement in glioma chemoresistance☆

(2008) Marie Le Mercier et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY