标题
Cell Transplantation and Gene Therapy in Parkinson's Disease
作者
关键词
-
出版物
MOUNT SINAI JOURNAL OF MEDICINE
Volume 78, Issue 1, Pages 126-158
出版商
Wiley
发表日期
2011-01-22
DOI
10.1002/msj.20233
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Preclinical Assessment of Stem Cell Therapies for Neurological Diseases
- (2013) V. L. Joers et al. ILAR JOURNAL
- Cell-based Therapeutic Approaches for Parkinson's Disease: Progress and Perspectives
- (2011) S.V. Anisimov REVIEWS IN THE NEUROSCIENCES
- Potential cellular and regenerative approaches for the treatment of Parkinson’s disease
- (2011) Emma Lane et al. Neuropsychiatric Disease and Treatment
- When Does Parkinson Disease Start?
- (2010) Rodolfo Savica et al. ARCHIVES OF NEUROLOGY
- Deep Brain Stimulation for Parkinson Disease
- (2010) Jeff M. Bronstein et al. ARCHIVES OF NEUROLOGY
- The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease
- (2010) Shane Grealish et al. BRAIN
- Efficient Derivation of Functional Floor Plate Tissue from Human Embryonic Stem Cells
- (2010) Christopher A. Fasano et al. Cell Stem Cell
- Patient-Specific Pluripotent Stem Cells Become Even More Accessible
- (2010) Shinya Yamanaka Cell Stem Cell
- Induction of pluripotency by defined factors
- (2010) Keisuke Okita et al. EXPERIMENTAL CELL RESEARCH
- Stem cells in human neurodegenerative disorders — time for clinical translation?
- (2010) Olle Lindvall et al. JOURNAL OF CLINICAL INVESTIGATION
- Differentiation of human ES and Parkinson's disease iPS cells into ventral midbrain dopaminergic neurons requires a high activity form of SHH, FGF8a and specific regionalization by retinoic acid
- (2010) Oliver Cooper et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Gene therapy for Parkinson's disease
- (2010) Tomas Bjorklund et al. MOVEMENT DISORDERS
- Characterization of Lewy body pathology in 12- and 16-year-old intrastriatal mesencephalic grafts surviving in a patient with Parkinson's disease
- (2010) Jia-Yi Li et al. MOVEMENT DISORDERS
- Role of serotonin neurons in the induction of levodopa- and graft-induced dyskinesias in Parkinson's disease
- (2010) Manolo Carta et al. MOVEMENT DISORDERS
- Epigenetic memory in induced pluripotent stem cells
- (2010) K. Kim et al. NATURE
- Nuclear reprogramming to a pluripotent state by three approaches
- (2010) Shinya Yamanaka et al. NATURE
- Direct conversion of fibroblasts to functional neurons by defined factors
- (2010) Thomas Vierbuchen et al. NATURE
- Cell type of origin influences the molecular and functional properties of mouse induced pluripotent stem cells
- (2010) Jose M Polo et al. NATURE BIOTECHNOLOGY
- Generation of mouse-induced pluripotent stem cells with plasmid vectors
- (2010) Keisuke Okita et al. Nature Protocols
- Prion-like transmission of protein aggregates in neurodegenerative diseases
- (2010) Patrik Brundin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Differentiation of non-mesencephalic neural stem cells towards dopaminergic neurons
- (2010) R. Rößler et al. NEUROSCIENCE
- Stem cell-derived dopamine neurons for brain repair in Parkinson’s disease
- (2010) Rosemary A Fricker-Gates et al. Regenerative Medicine
- Cellular Repair in the Parkinsonian Nonhuman Primate Brain
- (2010) Donald Eugene Redmond et al. REJUVENATION RESEARCH
- Serotonergic Neurons Mediate Dyskinesia Side Effects in Parkinson's Patients with Neural Transplants
- (2010) M. Politis et al. Science Translational Medicine
- Human Induced Pluripotent Stem Cells Develop Teratoma More Efficiently and Faster Than Human Embryonic Stem Cells Regardless the Site of Injection
- (2010) Ivan Gutierrez-Aranda et al. STEM CELLS
- The propagation of prion-like protein inclusions in neurodegenerative diseases
- (2010) Michel Goedert et al. TRENDS IN NEUROSCIENCES
- Staging/typing of Lewy body related α-synuclein pathology: a study of the BrainNet Europe Consortium
- (2009) Irina Alafuzoff et al. ACTA NEUROPATHOLOGICA
- Dopaminergic transplantation for parkinson's disease: Current status and future prospects
- (2009) C. Warren Olanow et al. ANNALS OF NEUROLOGY
- Lewy body pathology in fetal grafts
- (2009) Yaping Chu et al. Annals of the New York Academy of Sciences
- Parkinson's Disease
- (2009) Christopher H. Hawkes et al. Annals of the New York Academy of Sciences
- Cell-Based Therapies for Parkinson's Disease: Past, Present, and Future
- (2009) Kathleen M. Fitzpatrick et al. ANTIOXIDANTS & REDOX SIGNALING
- Scientific rationale for the development of gene therapy strategies for Parkinson's disease
- (2009) Tomas Björklund et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Parkinson's Disease Patient-Derived Induced Pluripotent Stem Cells Free of Viral Reprogramming Factors
- (2009) Frank Soldner et al. CELL
- Gene Therapy for Neurological Disorders: Challenges and Future Prospects for the Use of Growth Factors for the Treatment of Parkinsons Disease
- (2009) Fredric Manfredsson et al. CURRENT GENE THERAPY
- Cell-based therapies in Parkinson’s disease
- (2009) Paul Greene Current Neurology and Neuroscience Reports
- Coordination of sonic hedgehog and Wnt signaling determines ventral and dorsal telencephalic neuron types from human embryonic stem cells
- (2009) X.-J. Li et al. DEVELOPMENT
- Reconstruction of the nigrostriatal dopamine pathway in the adult mouse brain
- (2009) Lachlan H. Thompson et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Propagation of host disease to grafted neurons: Accumulating evidence
- (2009) Jeffrey H. Kordower et al. EXPERIMENTAL NEUROLOGY
- Embryonic substantia nigra grafts in the mesencephalon send neurites to the host striatum in non-human primate after overexpression of GDNF
- (2009) D.E. Redmond et al. JOURNAL OF COMPARATIVE NEUROLOGY
- Neuronal cell replacement in Parkinson’s disease
- (2009) E. Hedlund et al. JOURNAL OF INTERNAL MEDICINE
- Lack of functional relevance of isolated cell damage in transplants of Parkinson’s disease patients
- (2009) Oliver Cooper et al. JOURNAL OF NEUROLOGY
- Formation and development of Lewy pathology: a critical update
- (2009) Kurt A. Jellinger JOURNAL OF NEUROLOGY
- Positron Emission Tomography Imaging Demonstrates Correlation between Behavioral Recovery and Correction of Dopamine Neurotransmission after Gene Therapy
- (2009) L. Leriche et al. JOURNAL OF NEUROSCIENCE
- Tight Long-term Dynamic Doxycycline Responsive Nigrostriatal GDNF Using a Single rAAV Vector
- (2009) Fredric P Manfredsson et al. MOLECULAR THERAPY
- Virus-free induction of pluripotency and subsequent excision of reprogramming factors
- (2009) Keisuke Kaji et al. NATURE
- Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling
- (2009) Stuart M Chambers et al. NATURE BIOTECHNOLOGY
- Induced pluripotent stem cell technology for the study of human disease
- (2009) Gabsang Lee et al. NATURE METHODS
- Medical records documentation of constipation preceding Parkinson disease: A case-control study
- (2009) R. Savica et al. NEUROLOGY
- EXPRESSION, BIOACTIVITY, AND SAFETY 1 YEAR AFTER ADENO-ASSOCIATED VIRAL VECTOR TYPE 2–MEDIATED DELIVERY OF NEURTURIN TO THE MONKEY NIGROSTRIATAL SYSTEM SUPPORT CERE-120 FOR PARKINSON'S DISEASE
- (2009) Christopher D. Herzog et al. NEUROSURGERY
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells
- (2009) S. Friling et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Is Parkinson's disease a prion disorder?
- (2009) C. W. Olanow et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fetal Cells Again?
- (2009) C. Holden SCIENCE
- Cell Therapy Ahead for Parkinson's Disease
- (2009) O. Isacson SCIENCE
- Dopamine Gene Therapy for Parkinson's Disease in a Nonhuman Primate Without Associated Dyskinesia
- (2009) B. Jarraya et al. Science Translational Medicine
- Gene Therapy for Dopamine Replacement in Parkinsons Disease
- (2009) A. Bjorklund et al. Science Translational Medicine
- Prospects of stem cell therapy for replacing dopamine neurons in Parkinson's disease
- (2009) Olle Lindvall et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- One year survival and significant reversal of motor deficits in parkinsonian rats transplanted with hESC derived dopaminergic neurons
- (2008) Ravindran Geeta et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Cell replacement therapy for Parkinson's disease
- (2008) Ruwani Wijeyekoon et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A multitarget basal ganglia dopaminergic and GABAergic transplantation strategy enhances behavioural recovery in parkinsonian rats
- (2008) K. Mukhida et al. BRAIN
- Parthenogenetic dopamine neurons from primate embryonic stem cells restore function in experimental Parkinson's disease
- (2008) Rosario Sanchez-Pernaute et al. BRAIN
- Disease-Specific Induced Pluripotent Stem Cells
- (2008) In-Hyun Park et al. CELL
- Guidelines and Techniques for the Generation of Induced Pluripotent Stem Cells
- (2008) Nimet Maherali et al. Cell Stem Cell
- A High-Efficiency System for the Generation and Study of Human Induced Pluripotent Stem Cells
- (2008) Nimet Maherali et al. Cell Stem Cell
- Applications of Lentiviral Vectors for Biology and Gene Therapy of Neurological Disorders
- (2008) Cecilia Lundberg et al. CURRENT GENE THERAPY
- Potentials of ES Cell Therapy in Neurodegenerative Diseases
- (2008) Anand Srivastava et al. CURRENT PHARMACEUTICAL DESIGN
- AAV2-mediated gene transfer of GDNF to the striatum of MPTP monkeys enhances the survival and outgrowth of co-implanted fetal dopamine neurons
- (2008) J.D. Elsworth et al. EXPERIMENTAL NEUROLOGY
- Non-dopaminergic neurons in ventral mesencephalic transplants make widespread axonal connections in the host brain
- (2008) Lachlan H. Thompson et al. EXPERIMENTAL NEUROLOGY
- Human neural stem cells migrate along the nigrostriatal pathway in a primate model of Parkinson's disease
- (2008) Kimberly B. Bjugstad et al. EXPERIMENTAL NEUROLOGY
- Neurotrophic factors as a therapeutic target for Parkinson's disease
- (2008) Jonathan R Evans et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- GDNF therapy for Parkinson’s disease
- (2008) Murray Hong et al. Expert Review of Neurotherapeutics
- Immunity to adeno-associated virus vectors in animals and humans: a continued challenge
- (2008) A K Zaiss et al. GENE THERAPY
- Safety and tolerability of intraputaminal delivery of CERE-120 (adeno-associated virus serotype 2–neurturin) to patients with idiopathic Parkinson's disease: an open-label, phase I trial
- (2008) William J Marks et al. LANCET NEUROLOGY
- Differentiation of neural lineage cells from human pluripotent stem cells
- (2008) P SCHWARTZ et al. METHODS
- Transgene Expression, Bioactivity, and Safety of CERE-120 (AAV2-Neurturin) Following Delivery to the Monkey Striatum
- (2008) Christopher D Herzog et al. MOLECULAR THERAPY
- Clinical pattern and risk factors for dyskinesias following fetal nigral transplantation in Parkinson's disease: A double blind video-based analysis
- (2008) C. Warren Olanow et al. MOVEMENT DISORDERS
- Placebo response in Parkinson's disease: Comparisons among 11 trials covering medical and surgical interventions
- (2008) Christopher G. Goetz et al. MOVEMENT DISORDERS
- Placebo influences on dyskinesia in Parkinson's disease
- (2008) Christopher G. Goetz et al. MOVEMENT DISORDERS
- Transplanted dopaminergic neurons develop PD pathologic changes: A second case report
- (2008) Jeffrey H. Kordower et al. MOVEMENT DISORDERS
- The prodromal phase of sporadic Parkinson's disease: Does it exist and if so how long is it?
- (2008) Christopher H. Hawkes MOVEMENT DISORDERS
- Induction of pluripotent stem cells from primary human fibroblasts with only Oct4 and Sox2
- (2008) Danwei Huangfu et al. NATURE BIOTECHNOLOGY
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Absolute requirement of GDNF for adult catecholaminergic neuron survival
- (2008) Alberto Pascual et al. NATURE NEUROSCIENCE
- Efficient derivation of functional dopaminergic neurons from human embryonic stem cells on a large scale
- (2008) Myung-Soo Cho et al. Nature Protocols
- Generation of human-induced pluripotent stem cells
- (2008) In-Hyun Park et al. Nature Protocols
- Research in motion: the enigma of Parkinson's disease pathology spread
- (2008) Patrik Brundin et al. NATURE REVIEWS NEUROSCIENCE
- Results from a phase I safety trial of hAADC gene therapy for Parkinson disease
- (2008) J. L. Eberling et al. NEUROLOGY
- Lewy body pathology in long-term fetal nigral transplants: is parkinson's disease transmitted from one neural system to another?
- (2008) Jeffrey H Kordower et al. NEUROPSYCHOPHARMACOLOGY
- GENE AND CELL DELIVERY TO THE DEGENERATED STRIATUM
- (2008) R. Mark Richardson et al. NEUROSURGERY
- Recent advances in cell-based therapy for Parkinson disease
- (2008) Arnar Astradsson et al. Neurosurgical Focus
- Treatment of Parkinson’s disease with trophic factors
- (2008) Amie L. Peterson et al. Neurotherapeutics
- Therapeutic potentials of human embryonic stem cells in Parkinson’s disease
- (2008) Mary B. Newman et al. Neurotherapeutics
- Involvement of the serotonin system in l-dopa-induced dyskinesias
- (2008) Manolo Carta et al. PARKINSONISM & RELATED DISORDERS
- Neurons derived from reprogrammed fibroblasts functionally integrate into the fetal brain and improve symptoms of rats with Parkinson's disease
- (2008) M. Wernig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induced Pluripotent Stem Cells Generated Without Viral Integration
- (2008) M. Stadtfeld et al. SCIENCE
- Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors
- (2008) K. Okita et al. SCIENCE
- Directed Differentiation of Ventral Spinal Progenitors and Motor Neurons from Human Embryonic Stem Cells by Small Molecules
- (2008) Xue-Jun Li et al. STEM CELLS
- Noggin Enhances Dopamine Neuron Production from Human Embryonic Stem Cells and Improves Behavioral Outcome After Transplantation into Parkinsonian Rats
- (2008) Shunmei Chiba et al. STEM CELLS
- Embryonic Stem Cell-Derived Pitx3-Enhanced Green Fluorescent Protein Midbrain Dopamine Neurons Survive Enrichment by Fluorescence-Activated Cell Sorting and Function in an Animal Model of Parkinson's Disease
- (2008) Eva Hedlund et al. STEM CELLS
- The Role of Lmx1a in the Differentiation of Human Embryonic Stem Cells into Midbrain Dopamine Neurons in Culture and After Transplantation into a Parkinson's Disease Model
- (2008) Jingli Cai et al. STEM CELLS
- GDNF and GFRα: a versatile molecular complex for developing neurons
- (2008) Gustavo Paratcha et al. TRENDS IN NEUROSCIENCES
- Is deep brain stimulation neuroprotective if applied early in the course of PD?
- (2008) P David Charles et al. Nature clinical practice. Neurology
- Growth factors and feeder cells promote differentiation of human embryonic stem cell into dopaminergic neurons: a novel role of fibroblast growth factor-20
- (2008) Ana Sofia Correia Frontiers in Neuroscience
- Current status of gene therapy trials for Parkinson's disease
- (2007) Massimo Fiandaca et al. EXPERIMENTAL NEUROLOGY
- Preclinical development of gene therapy for Parkinson's disease
- (2007) Grégory Porras et al. EXPERIMENTAL NEUROLOGY
- Viral vectors for in vivo gene transfer in Parkinson's disease: Properties and clinical grade production
- (2007) Ronald J. Mandel et al. EXPERIMENTAL NEUROLOGY
- Design of clinical trials of gene therapy in Parkinson disease
- (2007) Travis B. Lewis et al. EXPERIMENTAL NEUROLOGY
- The need for regulatable vectors for gene therapy for Parkinson's disease
- (2007) Dean E. Cress EXPERIMENTAL NEUROLOGY
- Regulatable promoters and gene therapy for Parkinson's disease: Is the only thing to fear, fear itself?
- (2007) Jeffrey H. Kordower et al. EXPERIMENTAL NEUROLOGY
- Human neural progenitor cells over-expressing IGF-1 protect dopamine neurons and restore function in a rat model of Parkinson's disease
- (2007) Allison D. Ebert et al. EXPERIMENTAL NEUROLOGY
- Influence of cell preparation and target location on the behavioral recovery after striatal transplantation of fetal dopaminergic neurons in a primate model of Parkinson’s disease
- (2007) D.E. Redmond et al. NEUROBIOLOGY OF DISEASE
- Human Embryonic Stem Cell-Derived Dopaminergic Neurons Reverse Functional Deficit in Parkinsonian Rats
- (2007) Dali Yang et al. STEM CELLS
Publish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn MoreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started