Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy
出版年份 2014 全文链接
标题
Targeting BRCA1-BER deficient breast cancer by ATM or DNA-PKcs blockade either alone or in combination with cisplatin for personalized therapy
作者
关键词
-
出版物
Molecular Oncology
Volume 9, Issue 1, Pages 204-217
出版商
Wiley
发表日期
2014-08-28
DOI
10.1016/j.molonc.2014.08.001
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancer
- (2014) Tarek M.A. Abdel-Fatah et al. Molecular Oncology
- DNA polymerase β deficiency is linked to aggressive breast cancer: A comprehensive analysis of gene copy number, mRNA and protein expression in multiple cohorts
- (2014) Tarek M.A. Abdel-Fatah et al. Molecular Oncology
- 3-Aminobenzamide – a PARP inhibitor enhances the sensitivity of peripheral blood micronucleus and comet assays in mice
- (2014) Kamran Shekh et al. TOXICOLOGY MECHANISMS AND METHODS
- Expression of base excision repair key factors and miR17 in familial and sporadic breast cancer
- (2014) S De Summa et al. Cell Death & Disease
- Single-strand selective monofunctional uracil-DNA glycosylase (SMUG1) deficiency is linked to aggressive breast cancer and predicts response to adjuvant therapy
- (2013) Tarek M. A. Abdel-Fatah et al. BREAST CANCER RESEARCH AND TREATMENT
- Promoter methylation of BRCA1 in the prognosis of breast cancer: a meta-analysis
- (2013) Liang Wu et al. BREAST CANCER RESEARCH AND TREATMENT
- Clinicopathological significance of human apurinic/apyrimidinic endonuclease 1 (APE1) expression in oestrogen-receptor-positive breast cancer
- (2013) Tarek M. A. Abdel-Fatah et al. BREAST CANCER RESEARCH AND TREATMENT
- PARP-1 mechanism for coupling DNA damage detection to poly(ADP-ribose) synthesis
- (2013) Marie-France Langelier et al. CURRENT OPINION IN STRUCTURAL BIOLOGY
- The ATM protein kinase: regulating the cellular response to genotoxic stress and more
- (2013) Yosef Shiloh et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA double-strand-break complexity levels and their possible contributions to the probability for error-prone processing and repair pathway choice
- (2013) A. Schipler et al. NUCLEIC ACIDS RESEARCH
- Mammalian Base Excision Repair: the Forgotten Archangel
- (2013) Grigory L. Dianov et al. NUCLEIC ACIDS RESEARCH
- Methylation of BRCA1 Promoter Region Is Associated with Unfavorable Prognosis in Women with Early-Stage Breast Cancer
- (2013) Nicholas C. Hsu et al. PLoS One
- Interaction between DNA Polymerase β and BRCA1
- (2013) Aya Masaoka et al. PLoS One
- Targeting XRCC1 Deficiency in Breast Cancer for Personalized Therapy
- (2012) R. Sultana et al. CANCER RESEARCH
- The role of BRCA1 in DNA double-strand repair: Past and present
- (2012) Kevin W. Caestecker et al. EXPERIMENTAL CELL RESEARCH
- Clinicopathological and functional significance of XRCC1 expression in ovarian cancer
- (2012) Tarek Abdel-Fatah et al. INTERNATIONAL JOURNAL OF CANCER
- Enhancement of Synthetic Lethality via Combinations of ABT-888, a PARP Inhibitor, and Carboplatin In Vitro and In Vivo Using BRCA1 and BRCA2 Isogenic Models
- (2012) C. C. Clark et al. MOLECULAR CANCER THERAPEUTICS
- Playing the End Game: DNA Double-Strand Break Repair Pathway Choice
- (2012) J. Ross Chapman et al. MOLECULAR CELL
- The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups
- (2012) Christina Curtis et al. NATURE
- Mechanisms of BRCA1 Tumor Suppression: Figure 1.
- (2012) Daniel P. Silver et al. Cancer Discovery
- Further characterisation of the cellular activity of the DNA-PK inhibitor, NU7441, reveals potential cross-talk with homologous recombination
- (2011) Michele Tavecchio et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Induction and repair of DNA double strand breaks: The increasing spectrum of non-homologous end joining pathways
- (2011) Emil Mladenov et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Cytoscape 2.8: new features for data integration and network visualization
- (2010) M. E. Smoot et al. BIOINFORMATICS
- Loss of BRCA1 function increases the antitumor activity of cisplatin against human breast cancer xenografts in vivo
- (2010) Pierfrancesco Tassone et al. CANCER BIOLOGY & THERAPY
- BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair
- (2010) P. J. O'Donovan et al. CARCINOGENESIS
- The DNA-dependent protein kinase (DNA-PK): More than just a case of making ends meet?
- (2010) Richard Hill et al. CELL CYCLE
- Transcriptional Regulation of the Base Excision Repair Pathway by BRCA1
- (2010) Tapas Saha et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A validated gene expression profile for detecting clinical outcome in breast cancer using artificial neural networks
- (2009) L. J. Lancashire et al. BREAST CANCER RESEARCH AND TREATMENT
- Defective Repair of Oxidative DNA Damage in Triple-Negative Breast Cancer Confers Sensitivity to Inhibition of Poly(ADP-Ribose) Polymerase
- (2009) E. Alli et al. CANCER RESEARCH
- 53BP1 promotes ATM activity through direct interactions with the MRN complex
- (2009) Ji-Hoon Lee et al. EMBO JOURNAL
- DNA-Dependent Protein Kinase (DNA-PK)-Dependent Cisplatin-Induced Loss of Nucleolar Facilitator of Chromatin Transcription (FACT) and Regulation of Cisplatin Sensitivity by DNA-PK and FACT
- (2009) J. Dejmek et al. MOLECULAR CANCER RESEARCH
- Improved ATM kinase inhibitor KU-60019 radiosensitizes glioma cells, compromises insulin, AKT and ERK prosurvival signaling, and inhibits migration and invasion
- (2009) S. E. Golding et al. MOLECULAR CANCER THERAPEUTICS
- BRCA1 and its toolbox for the maintenance of genome integrity
- (2009) Michael S.Y. Huen et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Targeted therapy for cancer using PARP inhibitors
- (2008) Christopher J Lord et al. CURRENT OPINION IN PHARMACOLOGY
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