标题
Alpha-synuclein and tau: teammates in neurodegeneration?
作者
关键词
Tau, MAPT, Synuclein, SNCA, Oligomers, Tangles, Synucleinopathy, Tauopathy, Parkinson’s disease, Alzheimer’s disease
出版物
Molecular Neurodegeneration
Volume 9, Issue 1, Pages 43
出版商
Springer Nature
发表日期
2014-10-29
DOI
10.1186/1750-1326-9-43
参考文献
相关参考文献
注意：仅列出部分参考文献，下载原文获取全部文献信息。- Association Studies of Sporadic Parkinson’s Disease in the Genomic Era
- (2014) Catherine Labbe et al. CURRENT GENOMICS
- Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease
- (2014) Mike A Nalls et al. NATURE GENETICS
- Chronic Treatment with Novel Small Molecule Hsp90 Inhibitors Rescues Striatal Dopamine Levels but Not α-Synuclein-Induced Neuronal Cell Loss
- (2014) Nikolaus R. McFarland et al. PLoS One
- α-Synucleinopathy associated with G51D SNCA mutation: a link between Parkinson’s disease and multiple system atrophy?
- (2013) Aoife P. Kiely et al. ACTA NEUROPATHOLOGICA
- Peripheral administration of tau aggregates triggers intracerebral tauopathy in transgenic mice
- (2013) Florence Clavaguera et al. ACTA NEUROPATHOLOGICA
- Novel mutation in MAPT exon 13 (p.N410H) causes corticobasal degeneration
- (2013) Naomi Kouri et al. ACTA NEUROPATHOLOGICA
- LRRK2 phosphorylates novel tau epitopes and promotes tauopathy
- (2013) Rachel M. Bailey et al. ACTA NEUROPATHOLOGICA
- Prion-like spreading of pathological α-synuclein in brain
- (2013) Masami Masuda-Suzukake et al. BRAIN
- Distinct α-Synuclein Strains Differentially Promote Tau Inclusions in Neurons
- (2013) Jing L. Guo et al. CELL
- Genetic Correction of a LRRK2 Mutation in Human iPSCs Links Parkinsonian Neurodegeneration to ERK-Dependent Changes in Gene Expression
- (2013) Peter Reinhardt et al. Cell Stem Cell
- α-Synuclein Oligomers Impair Neuronal Microtubule-Kinesin Interplay
- (2013) Iryna Prots et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synthetic Tau Fibrils Mediate Transmission of Neurofibrillary Tangles in a Transgenic Mouse Model of Alzheimer's-Like Tauopathy
- (2013) M. Iba et al. JOURNAL OF NEUROSCIENCE
- Tau pathology and neurodegeneration
- (2013) Maria Grazia Spillantini et al. LANCET NEUROLOGY
- Drosophila melanogaster as a model organism for Alzheimer’s disease
- (2013) Katja Prüßing et al. Molecular Neurodegeneration
- Alpha-synuclein p.H50Q, a novel pathogenic mutation for Parkinson's disease
- (2013) Silke Appel-Cresswell et al. MOVEMENT DISORDERS
- Cerebrospinal fluid biomarkers in Parkinson disease
- (2013) Lucilla Parnetti et al. Nature Reviews Neurology
- Parkinson's disease dementia: convergence of α-synuclein, tau and amyloid-β pathologies
- (2013) David J. Irwin et al. NATURE REVIEWS NEUROSCIENCE
- Age-appropriate cognition and subtle dopamine-independent motor deficits in aged Tau knockout mice
- (2013) Meaghan Morris et al. NEUROBIOLOGY OF AGING
- A Powerful Yeast Model to Investigate the Synergistic Interaction of α-Synuclein and Tau in Neurodegeneration
- (2013) Gianmario Ciaccioli et al. PLoS One
- Age-Dependent Effects of A53T Alpha-Synuclein on Behavior and Dopaminergic Function
- (2013) Adam W. Oaks et al. PLoS One
- Transmission of multiple system atrophy prions to transgenic mice
- (2013) J. C. Watts et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Brain homogenates from human tauopathies induce tau inclusions in mouse brain
- (2013) Florence Clavaguera et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Evaluation of Potential Infectivity of Alzheimer and Parkinson Disease Proteins in Recipients of Cadaver-Derived Human Growth Hormone
- (2013) David J. Irwin et al. JAMA Neurology
- Targeting heat shock proteins to modulate α-synuclein toxicity
- (2013) Daryl Rhys Jones et al. Therapeutic Advances in Neurological Disorders
- Looking for novel functions of tau
- (2012) Jesus Avila et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- The role ofMAPTsequence variation in mechanisms of disease susceptibility: Figure 1
- (2012) Tara M. Caffrey et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Exosomal cell-to-cell transmission of alpha synuclein oligomers
- (2012) Karin M Danzer et al. Molecular Neurodegeneration
- Synergistic influence of phosphorylation and metal ions on tau oligomer formation and coaggregation with α-synuclein at the single molecule level
- (2012) Georg Nübling et al. Molecular Neurodegeneration
- The neuropathology of genetic Parkinson's disease
- (2012) Markos Poulopoulos et al. MOVEMENT DISORDERS
- Tau deficiency induces parkinsonism with dementia by impairing APP-mediated iron export
- (2012) Peng Lei et al. NATURE MEDICINE
- The MAPT locus—a genetic paradigm in disease susceptibility
- (2012) Richard Wade-Martins Nature Reviews Neurology
- MAPT H1 haplotype is associated with enhanced α-synuclein deposition in dementia with Lewy bodies
- (2012) Martí Colom-Cadena et al. NEUROBIOLOGY OF AGING
- LRRK2 Phosphorylates Tubulin-Associated Tau but Not the Free Molecule: LRRK2-Mediated Regulation of the Tau-Tubulin Association and Neurite Outgrowth
- (2012) Fumitaka Kawakami et al. PLoS One
- Paraquat, but Not Maneb, Induces Synucleinopathy and Tauopathy in Striata of Mice through Inhibition of Proteasomal and Autophagic Pathways
- (2012) Jonathan Wills et al. PLoS One
- Pathological -Synuclein Transmission Initiates Parkinson-like Neurodegeneration in Nontransgenic Mice
- (2012) K. C. Luk et al. SCIENCE
- Heat Shock Protein 70 Prevents both Tau Aggregation and the Inhibitory Effects of Preexisting Tau Aggregates on Fast Axonal Transport
- (2011) Kristina R. Patterson et al. BIOCHEMISTRY
- Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease
- (2011) Tiffany Kaul et al. BMC NEUROSCIENCE
- Hyperphosphorylated Tau in an α-synuclein-overexpressing transgenic model of Parkinson’s disease
- (2011) Thomas Haggerty et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β
- (2011) Fumitaka Kawakami et al. FEBS Journal
- Proteostasis of tau. Tau overexpression results in its secretion via membrane vesicles
- (2011) Diana Simón et al. FEBS LETTERS
- E46K Human α-Synuclein Transgenic Mice Develop Lewy-like and Tau Pathology Associated with Age-dependent, Detrimental Motor Impairment
- (2011) Kristel L. Emmer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of Intracellular Tau Aggregation Is Promoted by -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau
- (2011) E. A. Waxman et al. JOURNAL OF NEUROSCIENCE
- Wild type and P301L mutant Tau promote neuro-inflammation and α-Synuclein accumulation in lentiviral gene delivery models
- (2011) Preeti J. Khandelwal et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- MAPT H1 haplotype is a risk factor for essential tremor and multiple system atrophy
- (2011) C. Vilarino-Guell et al. NEUROLOGY
- Exogenous α-Synuclein Fibrils Induce Lewy Body Pathology Leading to Synaptic Dysfunction and Neuron Death
- (2011) Laura A. Volpicelli-Daley et al. NEURON
- Do interactions between SNCA, MAPT, and LRRK2 genes contribute to Parkinson’s disease susceptibility?
- (2011) Joanna M. Biernacka et al. PARKINSONISM & RELATED DISORDERS
- Neuropathological findings of PSP in the elderly without clinical PSP: Possible incidental PSP?
- (2011) Virgilio Gerald H. Evidente et al. PARKINSONISM & RELATED DISORDERS
- Tauopathic Changes in the Striatum of A53T α-Synuclein Mutant Mouse Model of Parkinson's Disease
- (2011) Jonathan Wills et al. PLoS One
- Tau Reduction Does Not Prevent Motor Deficits in Two Mouse Models of Parkinson's Disease
- (2011) Meaghan Morris et al. PLoS One
- Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy
- (2011) Nahuai Badiola et al. PLoS One
- Independent and joint effects of the MAPT and SNCA genes in Parkinson disease
- (2010) Alexis Elbaz et al. ANNALS OF NEUROLOGY
- SNCA,MAPT, andGSK3Bin Parkinson disease: a gene-gene interaction study
- (2010) C. Wider et al. EUROPEAN JOURNAL OF NEUROLOGY
- Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia
- (2010) Jonathan Wills et al. EXPERIMENTAL NEUROLOGY
- Interaction between α-synuclein and tau in Parkinson's disease
- (2010) Kurt A. Jellinger EXPERIMENTAL NEUROLOGY
- Parkinsonian Neurotoxin 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) and α-Synuclein Mutations Promote Tau Protein Phosphorylation at Ser262and Destabilize Microtubule Cytoskeletonin Vitro
- (2010) Hamid Y. Qureshi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Synergistic Interactions between A , Tau, and -Synuclein: Acceleration of Neuropathology and Cognitive Decline
- (2010) L. K. Clinton et al. JOURNAL OF NEUROSCIENCE
- Parkinson-related parkin reduces α-Synuclein phosphorylation in a gene transfer model
- (2010) Preeti J Khandelwal et al. Molecular Neurodegeneration
- Genetic Animal Models of Parkinson's Disease
- (2010) Ted M. Dawson et al. NEURON
- Absence of α-synuclein pathology in postencephalitic parkinsonism
- (2009) Kurt A. Jellinger ACTA NEUROPATHOLOGICA
- Threonine 53 in α-synuclein is conserved in long-living non-primate animals
- (2009) Knud Larsen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- The distinct cognitive syndromes of Parkinson's disease: 5 year follow-up of the CamPaIGN cohort
- (2009) Caroline H. Williams-Gray et al. BRAIN
- α-Synuclein contributes to GSK-3β-catalyzed Tau phosphorylation in Parkinson’s disease models
- (2009) Tetyana Duka et al. FASEB JOURNAL
- Propagation of Tau Misfolding from the Outside to the Inside of a Cell
- (2009) Bess Frost et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Seeding induced by α-synuclein oligomers provides evidence for spreading of α-synuclein pathology
- (2009) Karin M. Danzer et al. JOURNAL OF NEUROCHEMISTRY
- Brain-Permeable Small-Molecule Inhibitors of Hsp90 Prevent -Synuclein Oligomer Formation and Rescue -Synuclein-Induced Toxicity
- (2009) P. Putcha et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- What have worm models told us about the mechanisms of neuronal dysfunction in human neurodegenerative diseases?
- (2009) Dawn Teschendorf et al. Molecular Neurodegeneration
- The role of tau in neurodegeneration
- (2009) Tania F Gendron et al. Molecular Neurodegeneration
- Transmission and spreading of tauopathy in transgenic mouse brain
- (2009) Florence Clavaguera et al. NATURE CELL BIOLOGY
- Genome-wide association study reveals genetic risk underlying Parkinson's disease
- (2009) Javier Simón-Sánchez et al. NATURE GENETICS
- Evidence that incidental Lewy body disease is pre-symptomatic Parkinson’s disease
- (2008) Dennis W. Dickson et al. ACTA NEUROPATHOLOGICA
- Neurofibrillary tau pathology modulated by genetic variation of α-synuclein
- (2008) Terhi Peuralinna et al. ANNALS OF NEUROLOGY
- Sequence determinants regulating fibrillation of human α-synuclein
- (2008) Hyun-Jung Koo et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- RESEARCH ARTICLE: Empiric Refinement of the Pathologic Assessment of Lewy-Related Pathology in the Dementia Patient
- (2008) James B. Leverenz et al. BRAIN PATHOLOGY
- CHIP Targets Toxic α-Synuclein Oligomers for Degradation
- (2008) Julie E. Tetzlaff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Tau exon 10 alternative splicing and tauopathies
- (2008) Fei Liu et al. Molecular Neurodegeneration
- Lewy bodies in grafted neurons in subjects with Parkinson's disease suggest host-to-graft disease propagation
- (2008) Jia-Yi Li et al. NATURE MEDICINE
- Lewy body–like pathology in long-term embryonic nigral transplants in Parkinson's disease
- (2008) Jeffrey H Kordower et al. NATURE MEDICINE
- Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer’s disease, and in Parkinson’s disease and related α-synucleinopathies
- (2008) G. Muntané et al. NEUROSCIENCE
- Parkinsonism and impaired axonal transport in a mouse model of frontotemporal dementia
- (2008) L. M. Ittner et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
Become a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get StartedAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started