A Powerful Yeast Model to Investigate the Synergistic Interaction of α-Synuclein and Tau in Neurodegeneration

 -Synuclein in Parkinson's Disease

(2013) L. Stefanis   Cold Spring Harbor Perspectives in Medicine

Treatment Options for Tauopathies

(2012) Tarik Karakaya et al.   Current Treatment Options in Neurology

Accelerated Human Mutant Tau Aggregation by Knocking Out Murine Tau in a Transgenic Mouse Model

(2011) Kunie Ando et al.   AMERICAN JOURNAL OF PATHOLOGY

Stimulatory effect of α-synuclein on the tau-phosphorylation by GSK-3β

(2011) Fumitaka Kawakami et al.   FEBS Journal

The toxicity of tau in Alzheimer disease: turnover, targets and potential therapeutics

(2011) Susanne M. Pritchard et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Amyloid- /Fyn-Induced Synaptic, Network, and Cognitive Impairments Depend on Tau Levels in Multiple Mouse Models of Alzheimer's Disease

(2011) E. D. Roberson et al.   JOURNAL OF NEUROSCIENCE

Induction of Intracellular Tau Aggregation Is Promoted by  -Synuclein Seeds and Provides Novel Insights into the Hyperphosphorylation of Tau

(2011) E. A. Waxman et al.   JOURNAL OF NEUROSCIENCE

SNCA and MAPT genes: Independent and joint effects in Parkinson disease in the Italian population

(2011) Luca Trotta et al.   PARKINSONISM & RELATED DISORDERS

Tauopathic Changes in the Striatum of A53T α-Synuclein Mutant Mouse Model of Parkinson's Disease

(2011) Jonathan Wills et al.   PLoS One

Tau Reduction Does Not Prevent Motor Deficits in Two Mouse Models of Parkinson's Disease

(2011) Meaghan Morris et al.   PLoS One

Tau Enhances α-Synuclein Aggregation and Toxicity in Cellular Models of Synucleinopathy

(2011) Nahuai Badiola et al.   PLoS One

Expression of human FUS/TLS in yeast leads to protein aggregation and cytotoxicity, recapitulating key features of FUS proteinopathy

(2011) Kazuo Fushimi et al.   Protein & Cell

GSK3 and Alzheimer’s disease: facts and fiction…

(2011) Anna Kremer   Frontiers in Molecular Neuroscience

Independent and joint effects of the MAPT and SNCA genes in Parkinson disease

(2010) Alexis Elbaz et al.   ANNALS OF NEUROLOGY

Dendritic Function of Tau Mediates Amyloid-β Toxicity in Alzheimer's Disease Mouse Models

(2010) Lars M. Ittner et al.   CELL

Elevated tauopathy and alpha-synuclein pathology in postmortem Parkinson's disease brains with and without dementia

(2010) Jonathan Wills et al.   EXPERIMENTAL NEUROLOGY

Serine-409 phosphorylation and oxidative damage define aggregation of human protein tau in yeast

(2010) Thomas Vanhelmont et al.   FEMS YEAST RESEARCH

Tau protein: Relevance to Parkinson's disease

(2010) Peng Lei et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Aggregation of Detergent-insoluble Tau Is Involved in Neuronal Loss but Not in Synaptic Loss

(2010) Tetsuya Kimura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Genetics of Parkinson Disease

(2010) Lynn M. Bekris et al.   JOURNAL OF GERIATRIC PSYCHIATRY AND NEUROLOGY

LRRK2 G2019S Mutation Induces Dendrite Degeneration through Mislocalization and Phosphorylation of Tau by Recruiting Autoactivated GSK3 

(2010) C.-H. Lin et al.   JOURNAL OF NEUROSCIENCE

Yeast unfolds the road map toward α-synuclein-induced cell death

(2009) V Franssens et al.   CELL DEATH AND DIFFERENTIATION

Tau phosphorylation: the therapeutic challenge for neurodegenerative disease

(2009) Diane P. Hanger et al.   TRENDS IN MOLECULAR MEDICINE

Accumulation of phosphorylated TDP-43 in brains of patients with argyrophilic grain disease

(2008) Hiroshige Fujishiro et al.   ACTA NEUROPATHOLOGICA

Aggregates Assembled From Overexpression of Wild-Type α-Synuclein are not Toxic to Human Neuronal Cells

(2008) Li-wen Ko et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Phosphorylation of tau and α-synuclein in synaptic-enriched fractions of the frontal cortex in Alzheimer’s disease, and in Parkinson’s disease and related α-synucleinopathies

(2008) G. Muntané et al.   NEUROSCIENCE