The Binding Receptors of Aβ: an Alternative Therapeutic Target for Alzheimer’s Disease

Early Changes in Hippocampal Eph Receptors Precede the Onset of Memory Decline in Mouse Models of Alzheimer's Disease

(2017) Ana María Simón et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of N-terminal residues in Aβ interactions with integrin receptor and cell surface

(2014) Arundhathi Venkatasubramaniam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

PrPC signalling in neurons: From basics to clinical challenges

(2014) Théo Z. Hirsch et al.   BIOCHIMIE

High molecular mass assemblies of amyloid-β oligomers bind prion protein in patients with Alzheimer’s disease

(2014) Frank Dohler et al.   BRAIN

Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment

(2014) Jinsoo Seo et al.   CELL

Regulation of Presynaptic Ca2+, Synaptic Plasticity and Contextual Fear Conditioning by a N-terminal  -Amyloid Fragment

(2014) J. L. M. Lawrence et al.   JOURNAL OF NEUROSCIENCE

Peripheral Administration of a Humanized Anti-PrP Antibody Blocks Alzheimer's Disease A  Synaptotoxicity

(2014) I. Klyubin et al.   JOURNAL OF NEUROSCIENCE

Aβ Selectively Impairs mGluR7 Modulation of NMDA Signaling in Basal Forebrain Cholinergic Neurons: Implication in Alzheimer's Disease

(2014) Zhenglin Gu et al.   JOURNAL OF NEUROSCIENCE

Extrasynaptic NMDA Receptor Involvement in Central Nervous System Disorders

(2014) Matthew P. Parsons et al.   NEURON

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

β-Amyloid Inhibits E-S Potentiation through Suppression of Cannabinoid Receptor 1-Dependent Synaptic Disinhibition

(2014) Adrienne L. Orr et al.   NEURON

ApoE and Aβ in Alzheimer’s Disease: Accidental Encounters or Partners?

(2014) Takahisa Kanekiyo et al.   NEURON

Soluble Aβ Oligomers Are Rapidly Sequestered from Brain ISF In Vivo and Bind GM1 Ganglioside on Cellular Membranes

(2014) Soyon Hong et al.   NEURON

Lysosomal Sorting of Amyloid-  by the SORLA Receptor Is Impaired by a Familial Alzheimer's Disease Mutation

(2014) S. Caglayan et al.   Science Translational Medicine

The Role of Beta-Adrenergic Receptor Blockers in Alzheimer’s Disease

(2013) Khanh vinh quốc Lương et al.   American Journal of Alzheimers Disease and Other Dementias

β2Adrenergic Receptor, Protein Kinase A (PKA) and c-Jun N-terminal Kinase (JNK) Signaling Pathways Mediate Tau Pathology in Alzheimer Disease Models

(2013) Dayong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prion Protein-mediated Toxicity of Amyloid-β Oligomers Requires Lipid Rafts and the Transmembrane LRP1

(2013) Jo V. Rushworth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FcγRIIb mediates amyloid-β neurotoxicity and memory impairment in Alzheimer’s disease

(2013) Tae-In Kam et al.   JOURNAL OF CLINICAL INVESTIGATION

Multiple Roles of the p75 Neurotrophin Receptor in the Nervous System

(2013) Y Chen et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

A Novel Nicotinic Mechanism Underlies  -Amyloid-Induced Neuronal Hyperexcitation

(2013) Q. Liu et al.   JOURNAL OF NEUROSCIENCE

The role of synaptic activity in the regulation of amyloid beta levels in Alzheimer's disease

(2013) Xiaofang Cheng et al.   NEUROBIOLOGY OF AGING

Protective effects of EphB2 on Aβ1–42 oligomer-induced neurotoxicity and synaptic NMDA receptor signaling in hippocampal neurons

(2013) Dandan Geng et al.   NEUROCHEMISTRY INTERNATIONAL

Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion Protein

(2013) Ji Won Um et al.   NEURON

Environmental Novelty Activates β2-Adrenergic Signaling to Prevent the Impairment of Hippocampal LTP by Aβ Oligomers

(2013) Shaomin Li et al.   NEURON

Amyloid-β induced signaling by cellular prion protein and Fyn kinase in Alzheimer disease

(2013) Ji Won Um et al.   Prion

Human LilrB2 Is a  -Amyloid Receptor and Its Murine Homolog PirB Regulates Synaptic Plasticity in an Alzheimer's Model

(2013) T. Kim et al.   SCIENCE

A DR6/p75NTR complex is responsible for β-amyloid-induced cortical neuron death

(2013) Y Hu et al.   Cell Death & Disease

Synaptic Plasticity Defect Following Visual Deprivation in Alzheimer's Disease Model Transgenic Mice

(2012) C. M. William et al.   JOURNAL OF NEUROSCIENCE

Alzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons

(2012) Ji Won Um et al.   NATURE NEUROSCIENCE

Clinical and Biomarker Changes in Dominantly Inherited Alzheimer's Disease

(2012) Randall J. Bateman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cellular prion protein is essential for oligomeric amyloid- -induced neuronal cell death

(2011) W. Kudo et al.   HUMAN MOLECULAR GENETICS

Amyloid β Peptide-(1–42) Induces Internalization and Degradation of β2Adrenergic Receptors in Prefrontal Cortical Neurons

(2011) Dayong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Signaling through LRP1: Protection from atherosclerosis and beyond

(2010) Philippe Boucher et al.   BIOCHEMICAL PHARMACOLOGY

EphB Signaling Directs Peripheral Nerve Regeneration through Sox2-Dependent Schwann Cell Sorting

(2010) Simona Parrinello et al.   CELL

Binding of amyloid β peptide to β2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

(2010) Dayong Wang et al.   FASEB JOURNAL

Reversing EphB2 depletion rescues cognitive functions in Alzheimer model

(2010) Moustapha Cissé et al.   NATURE

The prion protein as a receptor for amyloid-β

(2010) Helmut W. Kessels et al.   NATURE

LRP1 mediates bidirectional transcytosis of amyloid-β across the blood-brain barrier

(2010) Thorsten Pflanzner et al.   NEUROBIOLOGY OF AGING

Distinct adrenergic system changes and neuroinflammation in response to induced locus ceruleus degeneration in APP/PS1 transgenic mice

(2010) D. Jardanhazi-Kurutz et al.   NEUROSCIENCE

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

ALDH1L1 inhibits cell motility via dephosphorylation of cofilin by PP1 and PP2A

(2010) N V Oleinik et al.   ONCOGENE

Locus ceruleus controls Alzheimer's disease pathology by modulating microglial functions through norepinephrine

(2010) M. T. Heneka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of the  7 Nicotinic Acetylcholine Receptor Gene Improves Cognitive Deficits and Synaptic Pathology in a Mouse Model of Alzheimer's Disease

(2009) G. Dziewczapolski et al.   JOURNAL OF NEUROSCIENCE

Cellular prion protein mediates impairment of synaptic plasticity by amyloid-β oligomers

(2009) Juha Laurén et al.   NATURE

Involvement of Fc Receptors in Disorders of the Central Nervous System

(2009) Eitan Okun et al.   NEUROMOLECULAR MEDICINE

Nicotinic Acetylcholine Receptor Signalling: Roles in Alzheimer's Disease and Amyloid Neuroprotection

(2009) S. D. Buckingham et al.   PHARMACOLOGICAL REVIEWS

The Prion's Elusive Reason for Being

(2008) Adriano Aguzzi et al.   Annual Review of Neuroscience

Polymorphisms at the β2-adrenergic receptor gene influence Alzheimer's disease susceptibility

(2008) Jin-Tai Yu et al.   BRAIN RESEARCH

The Role of the Cell Surface LRP and Soluble LRP in Blood-Brain Barrier Aβ Clearance in Alzheimers Disease

(2008) R. Deane et al.   CURRENT PHARMACEUTICAL DESIGN

E2-25K/Hip-2 regulates caspase-12 in ER stress–mediated Aβ neurotoxicity

(2008) Sungmin Song et al.   JOURNAL OF CELL BIOLOGY

 -Amyloid1-42 Induces Neuronal Death through the p75 Neurotrophin Receptor

(2008) A. Sotthibundhu et al.   JOURNAL OF NEUROSCIENCE

Amyloid-β protein dimers isolated directly from Alzheimer's brains impair synaptic plasticity and memory

(2008) Ganesh M Shankar et al.   NATURE MEDICINE

Inhibition of LTP by beta-amyloid is prevented by activation of β2 adrenoceptors and stimulation of the cAMP/PKA signalling pathway

(2008) Qin-wen Wang et al.   NEUROBIOLOGY OF AGING

EphB Receptors Couple Dendritic Filopodia Motility to Synapse Formation

(2008) Matthew S. Kayser et al.   NEURON

PirB is a Functional Receptor for Myelin Inhibitors of Axonal Regeneration

(2008) J. K. Atwal et al.   SCIENCE

Clusters of Hyperactive Neurons Near Amyloid Plaques in a Mouse Model of Alzheimer's Disease

(2008) M. A. Busche et al.   SCIENCE

β2 adrenergic agonist, clenbuterol, enhances working memory performance in aging animals

(2007) Brian P. Ramos et al.   NEUROBIOLOGY OF AGING