β2Adrenergic Receptor, Protein Kinase A (PKA) and c-Jun N-terminal Kinase (JNK) Signaling Pathways Mediate Tau Pathology in Alzheimer Disease Models

Dendritic Degeneration, Neurovascular Defects, and Inflammation Precede Neuronal Loss in a Mouse Model for Tau-Mediated Neurodegeneration

(2011) Tomasz Jaworski et al.   AMERICAN JOURNAL OF PATHOLOGY

Amyloid β Peptide-(1–42) Induces Internalization and Degradation of β2Adrenergic Receptors in Prefrontal Cortical Neurons

(2011) Dayong Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Roles of β-adrenergic receptors in Alzheimer's disease: Implications for novel therapeutics

(2010) Jin-Tai Yu et al.   BRAIN RESEARCH BULLETIN

Binding of amyloid β peptide to β2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity

(2010) Dayong Wang et al.   FASEB JOURNAL

A  Oligomers Cause Localized Ca2+ Elevation, Missorting of Endogenous Tau into Dendrites, Tau Phosphorylation, and Destruction of Microtubules and Spines

(2010) H. Zempel et al.   JOURNAL OF NEUROSCIENCE

Tau Mislocalization to Dendritic Spines Mediates Synaptic Dysfunction Independently of Neurodegeneration

(2010) Brian R. Hoover et al.   NEURON

Multiple Events Lead to Dendritic Spine Loss in Triple Transgenic Alzheimer's Disease Mice

(2010) Tobias Bittner et al.   PLoS One

 -Amyloid Oligomers Induce Phosphorylation of Tau and Inactivation of Insulin Receptor Substrate via c-Jun N-Terminal Kinase Signaling: Suppression by Omega-3 Fatty Acids and Curcumin

(2009) Q.-L. Ma et al.   JOURNAL OF NEUROSCIENCE

 -Amyloid Monomers Are Neuroprotective

(2009) M. L. Giuffrida et al.   JOURNAL OF NEUROSCIENCE

The JNK pathway amplifies and drives subcellular changes in tau phosphorylation

(2009) J. Vogel et al.   NEUROPHARMACOLOGY

AAV-Tau Mediates Pyramidal Neurodegeneration by Cell-Cycle Re-Entry without Neurofibrillary Tangle Formation in Wild-Type Mice

(2009) Tomasz Jaworski et al.   PLoS One

Effects of Cardiovascular Medications on Rate of Functional Decline in Alzheimer Disease

(2008) P.B. Rosenberg et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Role of central β-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge

(2008) John D. Johnson et al.   BRAIN BEHAVIOR AND IMMUNITY

Polymorphisms at the β2-adrenergic receptor gene influence Alzheimer's disease susceptibility

(2008) Jin-Tai Yu et al.   BRAIN RESEARCH

The β-Arrestin-2 Scaffold Protein Promotes c-Jun N-terminal Kinase-3 Activation by Binding to Its Nonconserved N Terminus

(2008) Chun Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY