Vitamin A Deficiency Impairs Spatial Learning and Memory: The Mechanism of Abnormal CBP-Dependent Histone Acetylation Regulated by Retinoic Acid Receptor Alpha

Early environmental factors, alteration of epigenetic marks and metabolic disease susceptibility

(2013) B. Portha et al.   BIOCHIMIE

Lysine Acetyltransferases CBP and p300 as Therapeutic Targets in Cognitive and Neurodegenerative Disorders

(2013) Luis Valor et al.   CURRENT PHARMACEUTICAL DESIGN

Retinoic acid receptor beta mediates all-trans retinoic acid facilitation of mesenchymal stem cells neuronal differentiation

(2013) Min Gong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

HDAC3 Is a Negative Regulator of Cocaine-Context-Associated Memory Formation

(2013) G. A. Rogge et al.   JOURNAL OF NEUROSCIENCE

Increasing Tip60 HAT Levels Rescues Axonal Transport Defects and Associated Behavioral Phenotypes in a Drosophila Alzheimer's Disease Model

(2013) A. A. Johnson et al.   JOURNAL OF NEUROSCIENCE

Loss of Histone Deacetylase 2 Improves Working Memory and Accelerates Extinction Learning

(2013) M. J. Morris et al.   JOURNAL OF NEUROSCIENCE

Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene

(2013) Kristian B. Laursen et al.   NUCLEIC ACIDS RESEARCH

A Naturally-Occurring Histone Acetyltransferase Inhibitor Derived from Garcinia indica Impairs Newly Acquired and Reactivated Fear Memories

(2013) Stephanie A. Maddox et al.   PLoS One

Distinct Roles for CBP and p300 on the RA-Mediated Expression of the Meiosis Commitment Gene Stra8 in Mouse Embryonic Stem Cells

(2013) Wen Chen et al.   PLoS One

Targeting of Histone Deacetylases to Reactivate Tumour Suppressor Genes and Its Therapeutic Potential in a Human Cervical Cancer Xenograft Model

(2013) Dingqing Feng et al.   PLoS One

Targeting specific HATs for neurodegenerative disease treatment: translating basic biology to therapeutic possibilities

(2013) Sheila K. Pirooznia et al.   Frontiers in Cellular Neuroscience

Exploring Epigenetic Regulation of Fear Memory and Biomarkers Associated with Post-Traumatic Stress Disorder

(2013) Stephanie A. Maddox et al.   Frontiers in Psychiatry

Why Are Genetics Important for Nutrition? Lessons from Epigenetic Research

(2012) Frank M. Ruemmele et al.   ANNALS OF NUTRITION AND METABOLISM

Factors Influencing Epigenetic Mechanisms and Related Diseases

(2012) Tom C. Karagiannis et al.   ANTIOXIDANTS & REDOX SIGNALING

Increasing Histone Acetylation in the Hippocampus-Infralimbic Network Enhances Fear Extinction

(2012) James M. Stafford et al.   BIOLOGICAL PSYCHIATRY

Acetylated tau, a novel pathological signature in Alzheimer's disease and other tauopathies

(2012) David J. Irwin et al.   BRAIN

Efficacy of the dietary histone deacetylase inhibitor butyrate alone or in combination with vitamin A against proliferation of MCF-7 human breast cancer cells

(2012) F.O. Andrade et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Reducing HDAC6 ameliorates cognitive deficits in a mouse model for Alzheimer's disease

(2012) Nambirajan Govindarajan et al.   EMBO Molecular Medicine

Daily patterns of clock and cognition-related factors are modified in the hippocampus of vitamin A-deficient rats

(2012) Rebeca S. Golini et al.   HIPPOCAMPUS

Vitamin A deficiency impairs postnatal cognitive function via inhibition of neuronal calcium excitability in hippocampus

(2012) Wei Jiang et al.   JOURNAL OF NEUROCHEMISTRY

Dysfunction of the RAR/RXR signaling pathway in the forebrain impairs hippocampal memory and synaptic plasticity

(2012) Masanori Nomoto et al.   Molecular Brain

p53 Regulates Cell Cycle and MicroRNAs to Promote Differentiation of Human Embryonic Stem Cells

(2012) Abhinav K. Jain et al.   PLOS BIOLOGY

Phase I study of the histone deacetylase inhibitor entinostat in combination with 13-cis retinoic acid in patients with solid tumours

(2011) R Pili et al.   BRITISH JOURNAL OF CANCER

Double null cells reveal that CBP and p300 are dispensable for p53 targetsp21andMdm2but variably required for target genes of other signaling pathways

(2011) Lawryn H. Kasper et al.   CELL CYCLE

Advancing Neuroscience Through Epigenetics: Molecular Mechanisms of Learning and Memory

(2011) David L. Molfese   DEVELOPMENTAL NEUROPSYCHOLOGY

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement

(2011) Jose P Lopez-Atalaya et al.   EMBO JOURNAL

Promoter context determines the role of proteasome in ligand-dependent occupancy of retinoic acid responsive elements

(2011) Aliaa Higazi et al.   Epigenetics

Effect of marginal vitamin A deficiency during pregnancy on retinoic acid receptors and N-methyl-d-aspartate receptor expression in the offspring of rats

(2011) Xuan Zhang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

HDAC inhibition modulates hippocampus-dependent long-term memory for object location in a CBP-dependent manner

(2011) J. Haettig et al.   LEARNING & MEMORY

Subregion-specific p300 conditional knock-out mice exhibit long-term memory impairments

(2011) A. M. M. Oliveira et al.   LEARNING & MEMORY

Hippocampal Focal Knockout of CBP Affects Specific Histone Modifications, Long-Term Potentiation and Long-Term Memory

(2011) Ruth M Barrett et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic regulation by RARα maintains ligand-independent transcriptional activity

(2011) Kristian B. Laursen et al.   NUCLEIC ACIDS RESEARCH

Epigenetic Alterations Are Critical for Fear Memory Consolidation and Synaptic Plasticity in the Lateral Amygdala

(2011) Melissa S. Monsey et al.   PLoS One

Influence of isotretinoin on hippocampal-based learning in human subjects

(2011) Anthony D. Ormerod et al.   PSYCHOPHARMACOLOGY

Perinatal Vitamin A Status in Relation to Neurodevelopmental Outcome at two Years of Age

(2010) Xuan Zhang et al.   INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH

Synergistic Effect of Retinoic Acid and Cytokines on the Regulation of Glial Fibrillary Acidic Protein Expression

(2010) Federico Herrera et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CREB Binding Protein Is Required for Both Short-Term and Long-Term Memory Formation

(2010) G. Chen et al.   JOURNAL OF NEUROSCIENCE

Vitamin A Upregulates Matrix Metalloproteinase-9 Activity by Murine Myeloid Dendritic Cells through a Nonclassical Transcriptional Mechanism

(2010) Denise E. Lackey et al.   JOURNAL OF NUTRITION

Spatial Memory Consolidation is Associated with Induction of Several Lysine-Acetyltransferase (Histone Acetyltransferase) Expression Levels and H2B/H4 Acetylation-Dependent Transcriptional Events in the Rat Hippocampus

(2010) Olivier Bousiges et al.   NEUROPSYCHOPHARMACOLOGY

Anti-Tumor Effect in Human Lung Cancer by a Combination Treatment of Novel Histone Deacetylase Inhibitors: SL142 or SL325 and Retinoic Acids

(2010) Shaoteng Han et al.   PLoS One

Epigenetic alterations regulate estradiol-induced enhancement of memory consolidation

(2010) Z. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of the Hyaluronan Synthase 2 Gene by Convergence in Cyclic AMP Response Element-binding Protein and Retinoid Acid Receptor Signaling

(2009) Katri M. Makkonen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HDAC2 negatively regulates memory formation and synaptic plasticity

(2009) Ji-Song Guan et al.   NATURE

Retinoid Signaling and Neurogenin2 Function Are Coupled for the Specification of Spinal Motor Neurons through a Chromatin Modifier CBP

(2009) Seunghee Lee et al.   NEURON

Beyond transcription factors: The role of chromatin modifying enzymes in regulating transcription required for memory

(2008) R. M. Barrett et al.   LEARNING & MEMORY

Extracellular Signals Regulate Rapid Coactivator Recruitment at AP-1 Sites by Altered Phosphorylation of both CREB Binding Protein and c-jun

(2008) L. N. Tsai et al.   MOLECULAR AND CELLULAR BIOLOGY