Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors
出版年份 2014 全文链接
标题
Hyperdiploid tumor cells increase phenotypic heterogeneity within Glioblastoma tumors
作者
关键词
-
出版物
Molecular BioSystems
Volume 10, Issue 4, Pages 741-758
出版商
Royal Society of Chemistry (RSC)
发表日期
2014-01-14
DOI
10.1039/c3mb70484j
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Epidermal Growth Factor Receptor in Glioma: Signal Transduction, Neuropathology, Imaging, and Radioresistance
- (2015) Kimmo J. Hatanpaa et al. NEOPLASIA
- The Brain Microenvironment Preferentially Enhances the Radioresistance of CD133+ Glioblastoma Stem-like Cells
- (2015) Muhammad Jamal et al. NEOPLASIA
- Three steps to the immortality of cancer cells: senescence, polyploidy and self-renewal
- (2013) Jekaterina Erenpreisa et al. Cancer Cell International
- Small-Molecule Inhibitor BMS-777607 Induces Breast Cancer Cell Polyploidy with Increased Resistance to Cytotoxic Chemotherapy Agents
- (2013) S. Sharma et al. MOLECULAR CANCER THERAPEUTICS
- Dynamics extracted from fixed cells reveal feedback linking cell growth to cell cycle
- (2013) Ran Kafri et al. NATURE
- Correlation between Ki67 and Breast Cancer Prognosis
- (2013) Konstantinos Kontzoglou et al. ONCOLOGY
- Survival and Death Strategies in Glioma Cells: Autophagy, Senescence and Apoptosis Triggered by a Single Type of Temozolomide-Induced DNA Damage
- (2013) Anna V. Knizhnik et al. PLoS One
- IGF1 Receptor Signaling Regulates Adaptive Radioprotection in Glioma Stem Cells
- (2013) Satoru Osuka et al. STEM CELLS
- MicroRNAs involved in chemo- and radioresistance of high-grade gliomas
- (2013) Andrej Besse et al. TUMOR BIOLOGY
- Pharmacologic stabilization of HIF-1 increases hematopoietic stem cell quiescence in vivo and accelerates blood recovery after severe irradiation
- (2012) C. E. Forristal et al. BLOOD
- Nicotine enhances proliferation, migration, and radioresistance of human malignant glioma cells through EGFR activation
- (2012) Ashraf A. Khalil et al. Brain Tumor Pathology
- A clinical review of treatment outcomes in glioblastoma multiforme—the validation in a non-trial population of the results of a randomised Phase III clinical trial: has a more radical approach improved survival?
- (2012) K Rock et al. BRITISH JOURNAL OF RADIOLOGY
- Telomere-Driven Tetraploidization Occurs in Human Cells Undergoing Crisis and Promotes Transformation of Mouse Cells
- (2012) Teresa Davoli et al. CANCER CELL
- Receptor Tyrosine Kinase Genes Amplified in Glioblastoma Exhibit a Mutual Exclusivity in Variable Proportions Reflective of Individual Tumor Heterogeneity
- (2012) S. E. Little et al. CANCER RESEARCH
- Resistance of Glioblastoma-Initiating Cells to Radiation Mediated by the Tumor Microenvironment Can Be Abolished by Inhibiting Transforming Growth Factor-β
- (2012) Matthew E. Hardee et al. CANCER RESEARCH
- Tetraploidization increases sensitivity to Aurora B kinase inhibition
- (2012) Miriam Marxer et al. CELL CYCLE
- Cell Size Control in Yeast
- (2012) Jonathan J. Turner et al. CURRENT BIOLOGY
- Chromosomal instability and aneuploidy in cancer: from yeast to man
- (2012) Sarah J Pfau et al. EMBO REPORTS
- Hypoxia and hypoxia-inducible factors in glioblastoma multiforme progression and therapeutic implications
- (2012) Liuqi Yang et al. EXPERIMENTAL CELL RESEARCH
- Molecular mechanisms of temozolomide resistance in glioblastoma multiforme
- (2012) Tor-Christian Aase Johannessen et al. Expert Review of Anticancer Therapy
- 2-Deoxy-D-glucose and 6-aminonicotinamide-mediated Nrf2 down regulation leads to radiosensitization of malignant cells via abrogation of GSH-mediated defense
- (2012) Pradeep Kumar Sharma et al. FREE RADICAL RESEARCH
- Polyploidy road to therapy-induced cellular senescence and escape
- (2012) Qin Wang et al. INTERNATIONAL JOURNAL OF CANCER
- The role of treatment modality on the utility of predictive tissue biomarkers in clinical prostate cancer: a systematic review
- (2012) Naveen Kachroo et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Quiescence and attenuated DNA damage response promote survival of esophageal cancer stem cells
- (2012) Yulin Chen et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- A Role for Homologous Recombination and Abnormal Cell-Cycle Progression in Radioresistance of Glioma-Initiating Cells
- (2012) Y. C. Lim et al. MOLECULAR CANCER THERAPEUTICS
- Clonal evolution in cancer
- (2012) Mel Greaves et al. NATURE
- A restricted cell population propagates glioblastoma growth after chemotherapy
- (2012) Jian Chen et al. NATURE
- Evolution of the cancer genome
- (2012) Lucy R. Yates et al. NATURE REVIEWS GENETICS
- Intratumoral heterogeneity of receptor tyrosine kinases EGFR and PDGFRA amplification in glioblastoma defines subpopulations with distinct growth factor response
- (2012) N. J. Szerlip et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Variable Clonal Repopulation Dynamics Influence Chemotherapy Response in Colorectal Cancer
- (2012) A. Kreso et al. SCIENCE
- Metabolite Profiling Identifies a Key Role for Glycine in Rapid Cancer Cell Proliferation
- (2012) M. Jain et al. SCIENCE
- Intratumor Heterogeneity: Seeing the Wood for the Trees
- (2012) T. A. Yap et al. Science Translational Medicine
- Radiation-Induced Reprogramming of Breast Cancer Cells
- (2012) Chann Lagadec et al. STEM CELLS
- LGR5-Positive Colon Cancer Stem Cells Interconvert with Drug-Resistant LGR5-Negative cells and are Capable of Tumor Reconstitution
- (2012) Shinta Kobayashi et al. STEM CELLS
- Polyploid cells rewire DNA damage response networks to overcome replication stress-induced barriers for tumour progression
- (2012) Li Zheng et al. Nature Communications
- The Causes and Consequences of Polyploidy in Normal Development and Cancer
- (2011) Teresa Davoli et al. Annual Review of Cell and Developmental Biology
- Evidence for label-retaining tumour-initiating cells in human glioblastoma
- (2011) Loic P. Deleyrolle et al. BRAIN
- Mosaic Amplification of Multiple Receptor Tyrosine Kinase Genes in Glioblastoma
- (2011) Matija Snuderl et al. CANCER CELL
- Heterogeneity Maintenance in Glioblastoma: A Social Network
- (2011) R. Bonavia et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5
- (2011) Santiago Rello-Varona et al. CELL CYCLE
- Promoter methylation and expression of MGMT and the DNA mismatch repair genes MLH1, MSH2, MSH6 and PMS2 in paired primary and recurrent glioblastomas
- (2011) Jörg Felsberg et al. INTERNATIONAL JOURNAL OF CANCER
- Tumorigenic polyploid cells contain elevated ROS and ARE selectively targeted by antioxidant treatment
- (2011) Meejeon Roh et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Improved survival time trends for glioblastoma using the SEER 17 population-based registries
- (2011) Matthew Koshy et al. JOURNAL OF NEURO-ONCOLOGY
- Targeting DNA repair and the cell cycle in glioblastoma
- (2011) Brian M. Alexander et al. JOURNAL OF NEURO-ONCOLOGY
- CERT depletion predicts chemotherapy benefit and mediates cytotoxic and polyploid-specific cancer cell death through autophagy induction
- (2011) Alvin J. X. Lee et al. JOURNAL OF PATHOLOGY
- Wnt activation is implicated in glioblastoma radioresistance
- (2011) Yonghyun Kim et al. LABORATORY INVESTIGATION
- Bortezomib resistance in a myeloma cell line is associated to PSMβ5 overexpression and polyploidy
- (2011) Patricia Balsas et al. LEUKEMIA RESEARCH
- Expanding fungal pathogenesis: Cryptococcus breaks out of the opportunistic box
- (2011) James W. Kronstad et al. NATURE REVIEWS MICROBIOLOGY
- Radioresistance of human glioma spheroids and expression of HSP70, p53 and EGFr
- (2011) Carlos A Fedrigo et al. Radiation Oncology
- Slow-Cycling Therapy-Resistant Cancer Cells
- (2011) Nathan Moore et al. STEM CELLS AND DEVELOPMENT
- Polyploidy and liver proliferation
- (2011) G. Gentric et al. Clinics and Research in Hepatology and Gastroenterology
- Scaling properties of cell and organelle size
- (2011) Yee-Hung M. Chan et al. Organogenesis
- How Darwinian models inform therapeutic failure initiated by clonal heterogeneity in cancer medicine
- (2010) M Gerlinger et al. BRITISH JOURNAL OF CANCER
- Pro-survival AKT and ERK signaling from EGFR and mutant EGFRvIII enhances DNA double-strand break repair in human glioma cells
- (2010) Sarah E. Golding et al. CANCER BIOLOGY & THERAPY
- Identification of Aneuploidy-Tolerating Mutations
- (2010) Eduardo M. Torres et al. CELL
- A Temporarily Distinct Subpopulation of Slow-Cycling Melanoma Cells Is Required for Continuous Tumor Growth
- (2010) Alexander Roesch et al. CELL
- Biological and Molecular Heterogeneity of Breast Cancers Correlates with Their Cancer Stem Cell Content
- (2010) Salvatore Pece et al. CELL
- Genomic Plasticity of the Human Fungal Pathogen Candida albicans
- (2010) Anna Selmecki et al. EUKARYOTIC CELL
- Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma
- (2010) M.-d.-M. Inda et al. GENES & DEVELOPMENT
- The origins of cancer robustness and evolvability
- (2010) Tianhai Tian et al. Integrative Biology
- Mitigation of hematologic radiation toxicity in mice through pharmacological quiescence induced by CDK4/6 inhibition
- (2010) Søren M. Johnson et al. JOURNAL OF CLINICAL INVESTIGATION
- Survival comparison between glioblastoma multiforme and other incurable cancers
- (2010) B. Tran et al. JOURNAL OF CLINICAL NEUROSCIENCE
- Immunologic Escape After Prolonged Progression-Free Survival With Epidermal Growth Factor Receptor Variant III Peptide Vaccination in Patients With Newly Diagnosed Glioblastoma
- (2010) John H. Sampson et al. JOURNAL OF CLINICAL ONCOLOGY
- Radiation Resistance in Glioma Cells Determined by DNA Damage Repair Activity of Ape1/Ref-1
- (2010) Mamta D. NAIDU et al. JOURNAL OF RADIATION RESEARCH
- Aneuploidy confers quantitative proteome changes and phenotypic variation in budding yeast
- (2010) Norman Pavelka et al. NATURE
- The landscape of somatic copy-number alteration across human cancers
- (2010) Rameen Beroukhim et al. NATURE
- The expression of mismatch repair proteins MLH1, MSH2 and MSH6 correlates with the Ki67 proliferation index and survival in patients with recurrent glioblastoma
- (2010) Andreas M. Stark et al. NEUROLOGICAL RESEARCH
- Clinical outcome in pediatric glial and embryonal brain tumors correlates with in vitro multi-passageable neurosphere formation
- (2010) Eduard H. Panosyan et al. PEDIATRIC BLOOD & CANCER
- Mitochondrial DNA Integrity Is Essential For Mitochondrial Maturation During Differentiation of Neural Stem Cells
- (2010) Wei Wang et al. STEM CELLS
- Cancer Stem Cells and Aneuploid Populations within Developing Tumors Are the Major Determinants of Tumor Dormancy
- (2009) A. P. Kusumbe et al. CANCER RESEARCH
- Characterization and functional analysis of a slow cycling stem cell-like subpopulation in pancreas adenocarcinoma
- (2009) Jennifer L. Dembinski et al. CLINICAL & EXPERIMENTAL METASTASIS
- MSH6 Mutations Arise in Glioblastomas during Temozolomide Therapy and Mediate Temozolomide Resistance
- (2009) S. Yip et al. CLINICAL CANCER RESEARCH
- The importance of surgical resection in malignant glioma
- (2009) Walter Stummer et al. CURRENT OPINION IN NEUROLOGY
- Irradiation With Carbon Ion Beams Induces Apoptosis, Autophagy, and Cellular Senescence in a Human Glioma-Derived Cell Line
- (2009) Atsushi Jinno-Oue et al. INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS
- Modulation of cellular radiation responses by 2-deoxy-D-glucose and other glycolytic inhibitors: Implications for cancer therapy
- (2009) VijayK Kalia et al. Journal of Cancer Research and Therapeutics
- IFNα activates dormant haematopoietic stem cells in vivo
- (2009) Marieke A. G. Essers et al. NATURE
- Formation of new chromosomes as a virulence mechanism in yeastCandida glabrata
- (2009) Silvia Poláková et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Radiation-induced Akt activation modulates radioresistance in human glioblastoma cells
- (2009) Hui-Fang Li et al. Radiation Oncology
- Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma
- (2009) Dan R. Laks et al. STEM CELLS
- Ploidy status and copy number aberrations in primary glioblastomas defined by integrated analysis of allelic ratios, signal ratios and loss of heterozygosity using 500K SNP Mapping Arrays
- (2008) Paul J Gardina et al. BMC GENOMICS
- Aneuploidy Underlies Rapid Adaptive Evolution of Yeast Cells Deprived of a Conserved Cytokinesis Motor
- (2008) Giulia Rancati et al. CELL
- Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair
- (2008) Anne Wilson et al. CELL
- Genistein induces radioprotection by hematopoietic stem cell quiescence
- (2008) Thomas A. Davis et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Correlation of O6-Methylguanine Methyltransferase (MGMT) Promoter Methylation With Clinical Outcomes in Glioblastoma and Clinical Strategies to Modulate MGMT Activity
- (2008) Monika E. Hegi et al. JOURNAL OF CLINICAL ONCOLOGY
- Immunohistochemical characteristics of melanoma
- (2008) Steven J. Ohsie et al. JOURNAL OF CUTANEOUS PATHOLOGY
- Aneuploidy Affects Proliferation and Spontaneous Immortalization in Mammalian Cells
- (2008) B. R. Williams et al. SCIENCE
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