Molecular Evolution of the Metazoan PHD–HIF Oxygen-Sensing System

Elasmobranch qPCR reference genes: a case study of hypoxia preconditioned epaulette sharks

(2010) Kalle T Rytkönen et al.   BMC MOLECULAR BIOLOGY

The hypoxia-inducible transcription factor pathway regulates oxygen sensing in the simplest animal, Trichoplax adhaerens

(2010) Christoph Loenarz et al.   EMBO REPORTS

Hypoxia-inducible factor (HIF)-3α is subject to extensive alternative splicing in human tissues and cancer cells and is regulated by HIF-1 but not HIF-2

(2010) Annika Pasanen et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Prolyl Hydroxylase Domain Inhibitors: A Route to HIF Activation and Neuroprotection

(2009) Sarah K. Harten et al.   ANTIOXIDANTS & REDOX SIGNALING

HIF Prolyl 4-Hydroxylases and their Potential as Drug Targets

(2009) Johanna Myllyharju   CURRENT PHARMACEUTICAL DESIGN

HIF Prolyl-4-hydroxylase Interacting Proteins: Consequences for Drug Targeting

(2009) Roland Wenger et al.   CURRENT PHARMACEUTICAL DESIGN

Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

(2009) Sandra Barth et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Generating specificity and diversity in the transcriptional response to hypoxia

(2009) Urban Lendahl et al.   NATURE REVIEWS GENETICS

Elephant shark (Callorhinchus milii) provides insights into the evolution of Hox gene clusters in gnathostomes

(2009) V. Ravi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Artificial ligand binding within the HIF2  PAS-B domain of the HIF2 transcription factor

(2009) T. H. Scheuermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural Basis for Binding of Hypoxia-Inducible Factor to the Oxygen-Sensing Prolyl Hydroxylases

(2009) Rasheduzzaman Chowdhury et al.   STRUCTURE

Two chaperonin systems in bacterial genomes with distinct ecological roles

(2009) Tom A. Williams et al.   TRENDS IN GENETICS

Genome-Wide Functional Divergence after the Symbiosis of Proteobacteria with Insects Unraveled through a Novel Computational Approach

(2009) Christina Toft et al.   PLoS Computational Biology

Rapidly evolving fish genomes and teleost diversity

(2008) Vydianathan Ravi et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Variable patterns in the molecular evolution of the hypoxia-inducible factor-1 alpha (HIF-1α) gene in teleost fishes and mammals

(2008) Kalle T. Rytkönen et al.   GENE

Timing of Genome Duplications Relative to the Origin of the Vertebrates: Did Cyclostomes Diverge before or after?

(2008) S. Kuraku et al.   MOLECULAR BIOLOGY AND EVOLUTION

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

The amphioxus genome and the evolution of the chordate karyotype

(2008) Nicholas H. Putnam et al.   NATURE

An Oxygen Molecular Sensor, the HIF Prolyl 4-Hydroxylase, in the Marine Protist Perkinsus olseni

(2008) Ricardo B. Leite et al.   PROTIST