Hypoxia-inducible Factor Prolyl-4-hydroxylase PHD2 Protein Abundance Depends on Integral Membrane Anchoring of FKBP38

FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism

(2008) Ahryon Cho et al.   DEVELOPMENTAL BIOLOGY

Imaging of the hypoxia-inducible factor pathway: insights into oxygen sensing

(2008) U. Berchner-Pfannschmidt et al.   EUROPEAN RESPIRATORY JOURNAL

Nuclear Oxygen Sensing: Induction of Endogenous Prolyl-hydroxylase 2 Activity by Hypoxia and Nitric Oxide

(2008) Utta Berchner-Pfannschmidt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway

(2008) William G. Kaelin et al.   MOLECULAR CELL

Inhibition of Siah ubiquitin ligase function

(2008) A Möller et al.   ONCOGENE

PHDs overactivation during chronic hypoxia "desensitizes" HIF  and protects cells from necrosis

(2008) A. Ginouves et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global Protein Stability Profiling in Mammalian Cells

(2008) H.-C. S. Yen et al.   SCIENCE

Regulation of adult erythropoiesis by prolyl hydroxylase domain proteins

(2007) K. Takeda et al.   BLOOD

Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure

(2007) Y. A. Minamishima et al.   BLOOD

Hypoxia-inducible Factor-1α Stabilization in Nonhypoxic Conditions: Role of Oxidation and Intracellular Ascorbate Depletion

(2007) Elisabeth L. Pagé et al.   MOLECULAR BIOLOGY OF THE CELL