EAF2 Suppresses Hypoxia-Induced Factor 1  Transcriptional Activity by Disrupting Its Interaction with Coactivator CBP/p300

Eaf1 and Eaf2 negatively regulate canonical Wnt/ -catenin signaling

(2013) J.-X. Liu et al.   DEVELOPMENT

Hypoxia-Inducible Factors in Physiology and Medicine

(2012) Gregg L. Semenza   CELL

The updated biology of hypoxia-inducible factor

(2012) Samantha N Greer et al.   EMBO JOURNAL

Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1

(2012) Maimon E. Hubbi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Upstream Stimulatory Factor 2 and Hypoxia-Inducible Factor 2  (HIF2 ) Cooperatively Activate HIF2 Target Genes during Hypoxia

(2012) M. R. Pawlus et al.   MOLECULAR AND CELLULAR BIOLOGY

The growing complexity of HIF-1α’s role in tumorigenesis: DNA repair and beyond

(2012) N Rohwer et al.   ONCOGENE

Normal glucose uptake in the brain and heart requires an endothelial cell-specific HIF-1 -dependent function

(2012) Y. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MUC1 mucin stabilizes and activates hypoxia-inducible factor 1 alpha to regulate metabolism in pancreatic cancer

(2012) N. V. Chaika et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular mechanisms mediating metastasis of hypoxic breast cancer cells

(2012) Gregg L. Semenza   TRENDS IN MOLECULAR MEDICINE

Metabolic reprogramming by HIF-1 promotes the survival of bone marrow-derived angiogenic cells in ischemic tissue

(2011) S. Rey et al.   BLOOD

Factor inhibiting HIF (FIH-1) promotes renal cancer cell survival by protecting cells from HIF-1α-mediated apoptosis

(2011) M N Khan et al.   BRITISH JOURNAL OF CANCER

SIRT3 Opposes Reprogramming of Cancer Cell Metabolism through HIF1α Destabilization

(2011) Lydia W.S. Finley et al.   CANCER CELL

Pyruvate Kinase M2 Is a PHD3-Stimulated Coactivator for Hypoxia-Inducible Factor 1

(2011) Weibo Luo et al.   CELL

p53 directly suppresses BNIP3 expression to protect against hypoxia-induced cell death

(2011) Xi Feng et al.   EMBO JOURNAL

MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1

(2011) Maimon E. Hubbi et al.   MOLECULAR CELL

Histone acetylation by CBP and p300 at double-strand break sites facilitates SWI/SNF chromatin remodeling and the recruitment of non-homologous end joining factors

(2011) H Ogiwara et al.   ONCOGENE

Zebrafish foxo3b Negatively Regulates Canonical Wnt Signaling to Affect Early Embryogenesis

(2011) Xun-wei Xie et al.   PLoS One

Metabolic state of glioma stem cells and nontumorigenic cells

(2011) E. Vlashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Histone Deacetylase Sirt6 Regulates Glucose Homeostasis via Hif1α

(2010) Lei Zhong et al.   CELL

Hypoxia and Hypoxia-Inducible Factors: Master Regulators of Metastasis

(2010) X. Lu et al.   CLINICAL CANCER RESEARCH

Small Ubiquitin-related Modifier (SUMO)-1 Promotes Glycolysis in Hypoxia

(2010) Terence A. Agbor et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation

(2010) Hongxia Z. Imtiyaz et al.   JOURNAL OF CLINICAL INVESTIGATION

Sirtuin 1 Modulates Cellular Responses to Hypoxia by Deacetylating Hypoxia-Inducible Factor 1α

(2010) Ji-Hong Lim et al.   MOLECULAR CELL

Hypoxia-Inducible Factors and the Response to Hypoxic Stress

(2010) Amar J. Majmundar et al.   MOLECULAR CELL

HIF-2  deletion promotes Kras-driven lung tumor development

(2010) J. Mazumdar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

An Essential Role of the HIF-1α-c-Myc Axis in Malignant Progression

(2009) Young-Gun Yoo et al.   Annals of the New York Academy of Sciences

U19/Eaf2 Binds to and Stabilizes von Hippel-Lindau Protein

(2009) W. Xiao et al.   CANCER RESEARCH

Hypoxia inducible factor-2α: a critical mediator of aggressive tumor phenotypes

(2009) Guoliang Qing et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Elongation Factor ELL (Eleven-Nineteen Lysine-rich Leukemia) Acts as a Transcription Factor for Direct Thrombospondin-1 Regulation

(2009) Jiangang Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

HIF-2α, but not HIF-1α, promotes iron absorption in mice

(2009) Maria Mastrogiannaki et al.   JOURNAL OF CLINICAL INVESTIGATION

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

Regulation of Hypoxia-Inducible Factor 2  Signaling by the Stress-Responsive Deacetylase Sirtuin 1

(2009) E. M. Dioum et al.   SCIENCE

Histone Acetyltransferase Inhibitor Anacardic Acid Causes Changes in Global Gene Expression during In VitroPlasmodium falciparumDevelopment

(2008) Long Cui et al.   EUKARYOTIC CELL

Molecular imaging of glucose uptake in oral neoplasia following topical application of fluorescently labeled deoxy-glucose

(2008) Nitin Nitin et al.   INTERNATIONAL JOURNAL OF CANCER

Hypoxia-Associated Factor, a Novel E3-Ubiquitin Ligase, Binds and Ubiquitinates Hypoxia-Inducible Factor 1 , Leading to Its Oxygen-Independent Degradation

(2008) M. Y. Koh et al.   MOLECULAR AND CELLULAR BIOLOGY

Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

(2008) E B Rankin et al.   ONCOGENE