The Functional Landscape of Hsp27 Reveals New Cellular Processes such as DNA Repair and Alternative Splicing and Proposes Novel Anticancer Targets

Inhibition of Hsp27 Radiosensitizes Head-and-Neck Cancer by Modulating Deoxyribonucleic Acid Repair

(2013) David M. Guttmann et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Translation Initiation Requires Cell Division Cycle 123 (Cdc123) to Facilitate Biogenesis of the Eukaryotic Initiation Factor 2 (eIF2)

(2013) Angelika F. Perzlmaier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A NETWORK-BASED APPROACH FOR PREDICTING HSP27 KNOCK-OUT TARGETS IN MOUSE SKELETAL MUSCLES

(2013) Malek Kammoun et al.   Computational and Structural Biotechnology Journal

Insights into RNA Biology from an Atlas of Mammalian mRNA-Binding Proteins

(2012) Alfredo Castello et al.   CELL

Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated withSLC45A3-ERGgene rearrangement and an unfavorable clinical course

(2012) Sven Perner et al.   INTERNATIONAL JOURNAL OF CANCER

Protein-Protein Interactions: Principles, Techniques, and their Potential Role in New Drug Development

(2012) Shagufta H. Khan et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

HECT and RING finger families of E3 ubiquitin ligases at a glance

(2012) M. B. Metzger et al.   JOURNAL OF CELL SCIENCE

Targeting TCTP as a New Therapeutic Strategy in Castration-resistant Prostate Cancer

(2012) Virginie Baylot et al.   MOLECULAR THERAPY

Protein interaction data curation: the International Molecular Exchange (IMEx) consortium

(2012) Sandra Orchard et al.   NATURE METHODS

SLC45A3-ELK4 Chimera in Prostate Cancer: Spotlight on cis -Splicing: Figure 1.

(2012) Chandan Kumar-Sinha et al.   Cancer Discovery

Multifunctional proteins revealed by overlapping clustering in protein interaction network

(2011) Emmanuelle Becker et al.   BIOINFORMATICS

Interactome Networks and Human Disease

(2011) Marc Vidal et al.   CELL

Inhibitors of Apoptosis Proteins (IAPs) as Potential Molecular Targets for Therapy of Hematological Malignancies

(2011) P. Smolewski et al.   CURRENT MOLECULAR MEDICINE

Toward an understanding of the protein interaction network of the human liver

(2011) J. Wang et al.   Molecular Systems Biology

Functional reconstitution of human eukaryotic translation initiation factor 3 (eIF3)

(2011) C. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Network-Based Tools for the Identification of Novel Drug Targets

(2011) I. J. Farkas et al.   Science Signaling

OGX-427 inhibits tumor progression and enhances gemcitabine chemotherapy in pancreatic cancer

(2011) V Baylot et al.   Cell Death & Disease

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

Abnormal interaction of motor neuropathy-associated mutant HspB8 (Hsp22) forms with the RNA helicase Ddx20 (gemin3)

(2010) Xiankui Sun et al.   CELL STRESS & CHAPERONES

Dynamic processes that reflect anti-apoptotic strategies set up by HspB1 (Hsp27)

(2010) Catherine Paul et al.   EXPERIMENTAL CELL RESEARCH

CHIP Promotes Human Telomerase Reverse Transcriptase Degradation and Negatively Regulates Telomerase Activity

(2010) Ji Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interactome Mapping of the Phosphatidylinositol 3-Kinase-Mammalian Target of Rapamycin Pathway Identifies Deformed Epidermal Autoregulatory Factor-1 as a New Glycogen Synthase Kinase-3 Interactor

(2010) Fanny Pilot-Storck et al.   MOLECULAR & CELLULAR PROTEOMICS

The mechanism of eukaryotic translation initiation and principles of its regulation

(2010) Richard J. Jackson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Heat shock protein 27 confers resistance to androgen ablation and chemotherapy in prostate cancer cells through eIF4E

(2010) C Andrieu et al.   ONCOGENE

SimCT: a generic tool to visualize ontology-based relationships for biological objects

(2009) Carl Herrmann et al.   BIOINFORMATICS

Recent Advances in Cancer Therapy Targeting Proteins Involved in DNA Double-Strand Break Repair

(2009) E. Bolderson et al.   CLINICAL CANCER RESEARCH

Tissue specificity and the human protein interaction network

(2009) Alice Bossi et al.   Molecular Systems Biology

DNA double-strand breaks: Their production, recognition, and repair in eukaryotes

(2009) Takeo Ohnishi et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Cellular stress and RNA splicing

(2009) Giuseppe Biamonti et al.   TRENDS IN BIOCHEMICAL SCIENCES

HSP27 regulates p53 transcriptional activity in doxorubicin-treated fibroblasts and cardiac H9c2 cells: p21 upregulation and G2/M phase cell cycle arrest

(2008) C. D. Venkatakrishnan et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The Hsp90 molecular chaperone: an open and shut case for treatment

(2008) Laurence H. Pearl et al.   BIOCHEMICAL JOURNAL

FIRMA: a method for detection of alternative splicing from exon array data

(2008) E. Purdom et al.   BIOINFORMATICS

The spliceosome as target for anticancer treatment

(2008) R J van Alphen et al.   BRITISH JOURNAL OF CANCER

A Protein Domain-Based Interactome Network for C. elegans Early Embryogenesis

(2008) Mike Boxem et al.   CELL

Guidelines for the nomenclature of the human heat shock proteins

(2008) Harm H. Kampinga et al.   CELL STRESS & CHAPERONES

An empirical framework for binary interactome mapping

(2008) Kavitha Venkatesan et al.   NATURE METHODS

An experimentally derived confidence score for binary protein-protein interactions

(2008) Pascal Braun et al.   NATURE METHODS

DNA repair of clustered lesions in mammalian cells: involvement of non-homologous end-joining

(2008) S. Malyarchuk et al.   NUCLEIC ACIDS RESEARCH

Identification of multi-SH3 domain-containing protein interactome in pancreatic cancer: A yeast two-hybrid approach

(2008) Subhash Thalappilly et al.   PROTEOMICS