Effects of FGF-2 and FGF receptor antagonists on MMP enzymes, aggrecan, and type II collagen in primary human OA chondrocytes

Intraarticular Sprifermin (Recombinant Human Fibroblast Growth Factor 18) in Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Trial

(2014) L. Stefan Lohmander et al.   Arthritis & Rheumatology

Attenuation of TNF production and experimentally induced inflammation by PDE4 inhibitor rolipram is mediated by MAPK phosphatase-1

(2013) Riku Korhonen et al.   BRITISH JOURNAL OF PHARMACOLOGY

Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice

(2012) Tujun Weng et al.   ARTHRITIS AND RHEUMATISM

AZD4547: An Orally Bioavailable, Potent, and Selective Inhibitor of the Fibroblast Growth Factor Receptor Tyrosine Kinase Family

(2012) P. R. Gavine et al.   CANCER RESEARCH

Species-specific biological effects of FGF-2 in articular cartilage: Implication for distinct roles within the FGF receptor family

(2012) Xin Li et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Fibroblast growth factor control of cartilage homeostasis

(2012) M.B. Ellman et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Adiponectin associates with markers of cartilage degradation in osteoarthritis and induces production of proinflammatory and catabolic factors through mitogen-activated protein kinase pathways

(2012) Anna Koskinen et al.   ARTHRITIS RESEARCH & THERAPY

The Role of Growth Factors in Cartilage Repair

(2011) Lisa A. Fortier et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Correlation between plasma and synovial fluid basic fibroblast growth factor with radiographic severity in primary knee osteoarthritis

(2011) Sittisak Honsawek et al.   INTERNATIONAL ORTHOPAEDICS

Discovery of 3-(2,6-Dichloro-3,5-dimethoxy-phenyl)-1-{6-[4-(4-ethyl-piperazin-1-yl)-phenylamino]-pyrimidin-4-yl}-1-methyl-urea (NVP-BGJ398), A Potent and Selective Inhibitor of the Fibroblast Growth Factor Receptor Family of Receptor Tyrosine Kinase

(2011) Vito Guagnano et al.   JOURNAL OF MEDICINAL CHEMISTRY

Fibroblast growth factor 2: good or bad guy in the joint?

(2011) Tonia L Vincent   ARTHRITIS RESEARCH & THERAPY

Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes

(2011) Dongyao Yan et al.   ARTHRITIS RESEARCH & THERAPY

The role of the cartilage matrix in osteoarthritis

(2010) Dick Heinegård et al.   Nature Reviews Rheumatology

Role of proinflammatory cytokines in the pathophysiology of osteoarthritis

(2010) Mohit Kapoor et al.   Nature Reviews Rheumatology

Fibroblast growth factor 2 is an intrinsic chondroprotective agent that suppresses ADAMTS-5 and delays cartilage degradation in murine osteoarthritis

(2009) Shi-Lu Chia et al.   ARTHRITIS AND RHEUMATISM

Inhibition of histone deacetylases antagonized FGF2 and IL-1β effects on MMP expression in human articular chondrocytes

(2009) Xibin Wang et al.   GROWTH FACTORS

Fibroblast growth factor 2 inhibits induction of aggrecanase activity in human articular cartilage

(2008) Yasunobu Sawaji et al.   ARTHRITIS AND RHEUMATISM