The theft of host heme by Gram-positive pathogenic bacteria

The heme sensing response regulator HssR in Staphylococcus aureus but not the homologous RR23 in Listeria monocytogenes modulates susceptibility to the antimicrobial peptide plectasin

(2010) Line E Thomsen et al.   BMC MICROBIOLOGY

Staphylococcus aureus Fur Regulates the Expression of Virulence Factors That Contribute to the Pathogenesis of Pneumonia

(2010) V. J. Torres et al.   INFECTION AND IMMUNITY

Overcoming the Heme Paradox: Heme Toxicity and Tolerance in Bacterial Pathogens

(2010) L. L. Anzaldi et al.   INFECTION AND IMMUNITY

Fur is required for the activation of virulence gene expression through the induction of the sae regulatory system in Staphylococcus aureus

(2010) Miranda Johnson et al.   INTERNATIONAL JOURNAL OF MEDICAL MICROBIOLOGY

A Bacillus anthracis S-Layer Homology Protein That Binds Heme and Mediates Heme Delivery to IsdC

(2010) Y. Tarlovsky et al.   JOURNAL OF BACTERIOLOGY

The ABC Transporter HrtAB Confers Resistance to Hemin Toxicity and Is Regulated in a Hemin-Dependent Manner by the ChrAS Two-Component System in Corynebacterium diphtheriae

(2010) L. A. Bibb et al.   JOURNAL OF BACTERIOLOGY

Iron-containing lipoprotein SiaA in SiaABC, the primary heme transporter of Streptococcus pyogenes

(2010) Xuesong Sun et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

The IsdG-family of haem oxygenases degrades haem to a novel chromophore

(2010) Michelle L. Reniere et al.   MOLECULAR MICROBIOLOGY

Shr of group A streptococcus is a new type of composite NEAT protein involved in sequestering haem from methaemoglobin

(2010) Mahamoudou Ouattara et al.   MOLECULAR MICROBIOLOGY

IsdA and IsdB antibodies protect mice against Staphylococcus aureus abscess formation and lethal challenge

(2010) Hwan Keun Kim et al.   VACCINE

Two Coregulated Efflux Transporters Modulate Intracellular Heme and Protoporphyrin IX Availability in Streptococcus agalactiae

(2010) Annabelle Fernandez et al.   PLoS Pathogens

Membrane Damage Elicits an Immunomodulatory Program in Staphylococcus aureus

(2010) Ahmed S. Attia et al.   PLoS Pathogens

Trafficking of Heme and Porphyrins in Metazoa

(2009) Scott Severance et al.   CHEMICAL REVIEWS

This Is Not Your Mother's Repressor: the Complex Role of Fur in Pathogenesis

(2009) B. M. Carpenter et al.   INFECTION AND IMMUNITY

HtaA Is an Iron-Regulated Hemin Binding Protein Involved in the Utilization of Heme Iron in Corynebacterium diphtheriae

(2009) C. E. Allen et al.   JOURNAL OF BACTERIOLOGY

Heme Transfer to the Bacterial Cell Envelope Occurs via a Secreted Hemophore in the Gram-positive PathogenBacillus anthracis

(2009) Marian Fabian et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The SaeR/S Gene Regulatory System Is Essential for Innate Immune Evasion byStaphylococcus aureus

(2009) Jovanka M. Voyich et al.   JOURNAL OF INFECTIOUS DISEASES

SaeR Binds a Consensus Sequence within Virulence Gene Promoters to Advance USA300 Pathogenesis

(2009) Tyler K. Nygaard et al.   JOURNAL OF INFECTIOUS DISEASES

Structural biology of heme binding in the Staphylococcus aureus Isd system

(2009) Jason C. Grigg et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Differential gene expression in Streptococcus pneumoniae in response to various iron sources

(2009) R. Gupta et al.   MICROBIAL PATHOGENESIS

Bacillus anthracisHssRS signalling to HrtAB regulates haem resistance during infection

(2009) Devin L. Stauff et al.   MOLECULAR MICROBIOLOGY

Transcriptional Profiling of Bacillus anthracis Sterne (34F2) during Iron Starvation

(2009) Paul E. Carlson et al.   PLoS One

Bacteria capture iron from heme by keeping tetrapyrrol skeleton intact

(2009) Sylvie Létoffé et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IlsA, A Unique Surface Protein of Bacillus cereus Required for Iron Acquisition from Heme, Hemoglobin and Ferritin

(2009) Nadine Daou et al.   PLoS Pathogens

Bacterial heme-transport proteins and their heme-coordination modes

(2008) Yong Tong et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Characterization of SiaA, a Streptococcal Heme-Binding Protein Associated with a Heme ABC Transport System†

(2008) Brian R. Sook et al.   BIOCHEMISTRY

The surface protein Shr of Streptococcus pyogenes binds heme and transfers it to the streptococcal heme-binding protein Shp

(2008) Hui Zhu et al.   BMC MICROBIOLOGY

IsdA Protects Staphylococcus aureus against the Bactericidal Protease Activity of Apolactoferrin

(2008) S. R. Clarke et al.   INFECTION AND IMMUNITY

Staphylococcus aureus HrtA Is an ATPase Required for Protection against Heme Toxicity and Prevention of a Transcriptional Heme Stress Response

(2008) D. L. Stauff et al.   JOURNAL OF BACTERIOLOGY

Ruffling of Metalloporphyrins Bound to IsdG and IsdI, Two Heme-degrading Enzymes inStaphylococcus aureus

(2008) Woo Cheol Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functionally Distinct NEAT (NEAr Transporter) Domains within theStaphylococcus aureusIsdH/HarA Protein Extract Heme from Methemoglobin

(2008) Rosemarie M. Pilpa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pathway for Heme Uptake from Human Methemoglobin by the Iron-regulated Surface Determinants System ofStaphylococcus aureus

(2008) Hui Zhu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for Multimeric Heme Complexation through a Specific Protein-Heme Interaction

(2008) Masato Watanabe et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Demonstration of the Iron-regulated Surface Determinant (Isd) Heme Transfer Pathway inStaphylococcus aureus

(2008) Naomi Muryoi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Direct Hemin Transfer from IsdA to IsdC in the Iron-regulated Surface Determinant (Isd) Heme Acquisition System ofStaphylococcus aureus

(2008) Mengyao Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Staphylococcus aureushaem oxygenases are differentially regulated by iron and haem

(2008) Michelle L. Reniere et al.   MOLECULAR MICROBIOLOGY

Bacillus anthracis Secretes Proteins That Mediate Heme Acquisition from Hemoglobin

(2008) Anthony W. Maresso et al.   PLoS Pathogens