Evaluation of cardiovascular parameters in cynomolgus monkeys following IV administration of LBR-101, a monoclonal antibody against calcitonin gene-related peptide

Safety and tolerability of LBR-101, a humanized monoclonal antibody that blocks the binding of CGRP to its receptor: Results of the Phase 1 program

(2013) Marcelo E Bigal et al.   CEPHALALGIA

The Pipeline in Headache Therapy

(2013) Sarah Vollbracht et al.   CNS DRUGS

Calcitonin Gene-Related Peptide (CGRP) and Migraine Current Understanding and State of Development

(2013) Marcelo E. Bigal et al.   HEADACHE

A Randomized, Placebo-Controlled Study of the Effects of Telcagepant on Exercise Time in Patients With Stable Angina

(2012) B R Chaitman et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Emerging Target-Based Paradigms to Prevent and Treat Migraine

(2012) S D Silberstein   CLINICAL PHARMACOLOGY & THERAPEUTICS

Central ventilatory and cardiovascular actions of calcitonin gene-related peptide in unanesthetized trout

(2012) J.-C. Le Mevel et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Compensatory vasodilatation during hypoxic exercise: mechanisms responsible for matching oxygen supply to demand

(2012) Darren P. Casey et al.   JOURNAL OF PHYSIOLOGY-LONDON

Randomized controlled trial of the CGRP receptor antagonist MK-3207 in the acute treatment of migraine

(2011) David J Hewitt et al.   CEPHALALGIA

New Agents for Acute Treatment of Migraine: CGRP Receptor Antagonists, iNOS Inhibitors

(2011) Jan Hoffmann et al.   Current Treatment Options in Neurology

Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation

(2011) Ann C. Raddant et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Electrocardiographic assessment for therapeutic proteins—scientific discussion

(2010) Ignacio Rodriguez et al.   AMERICAN HEART JOURNAL

The potent calcitonin gene-related peptide receptor antagonist, telcagepant, does not affect nitroglycerin-induced vasodilation in healthy men

(2010) Bart J. Van der Schueren et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Mice Lacking the Neuropeptide α-Calcitonin Gene-Related Peptide Are Protected Against Diet-Induced Obesity

(2010) Christopher S. Walker et al.   ENDOCRINOLOGY

Effect of Calcitonin Gene-Related Peptide Receptor Antagonism on the Systemic Blood Pressure Responses to Mechanistically Diverse Vasomodulators in Conscious Rats

(2010) Joseph J Lynch et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

Characterization of the Calcitonin Gene-Related Peptide Receptor Antagonist Telcagepant (MK-0974) in Human Isolated Coronary Arteries

(2010) K. Y. Chan et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

CGRP and its receptors provide new insights into migraine pathophysiology

(2010) Tony W. Ho et al.   Nature Reviews Neurology

Henry Cuthbert Bazett (1885-1950)-The Man behind the QT Interval Correction Formula

(2010) ARIEL ROGUIN   PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY

Possible sites of action of the new calcitonin gene-related peptide receptor antagonists

(2010) Sajedeh Eftekhari et al.   Therapeutic Advances in Neurological Disorders

Effects of the prototype serotonin 5-HT1B/1D receptor agonist sumatriptan and the calcitonin gene-related peptide (CGRP) receptor antagonist CGRP8–37 on myocardial reactive hyperemic response in conscious dogs

(2009) Joseph J. Lynch et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

CGRP function-blocking antibodies inhibit neurogenic vasodilatation without affecting heart rate or arterial blood pressure in the rat

(2008) J Zeller et al.   BRITISH JOURNAL OF PHARMACOLOGY

Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial

(2008) Tony W Ho et al.   LANCET