The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis
出版年份 2018 全文链接
标题
The STAT3 inhibitor S3I-201 suppresses fibrogenesis and angiogenesis in liver fibrosis
作者
关键词
-
出版物
LABORATORY INVESTIGATION
Volume -, Issue -, Pages -
出版商
Springer Nature America, Inc
发表日期
2018-09-12
DOI
10.1038/s41374-018-0127-3
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Transforming Growth Factor-β (TGF-β) Directly Activates the JAK1-STAT3 Axis to Induce Hepatic Fibrosis in Coordination with the SMAD Pathway
- (2017) Liu-Ya Tang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- TGF-β signalling and liver disease
- (2016) Isabel Fabregat et al. FEBS Journal
- Pathobiology of liver fibrosis: a translational success story
- (2015) Youngmin A Lee et al. GUT
- Hepatic fibrosis: Concept to treatment
- (2015) Christian Trautwein et al. JOURNAL OF HEPATOLOGY
- STAT3 selectively interacts with Smad3 to antagonize TGF-β
- (2015) G Wang et al. ONCOGENE
- Correction: Brivanib Attenuates Hepatic Fibrosis In Vivo and Stellate Cell Activation In Vitro by Inhibition of FGF, VEGF and PDGF Signaling
- (2015) Ikuo Nakamura et al. PLoS One
- Sorafenib and its derivative SC-1 exhibit antifibrotic effects through signal transducer and activator of transcription 3 inhibition
- (2015) Tung-Hung Su et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Stat3 signaling activation crosslinking of TGF-β1 in hepatic stellate cell exacerbates liver injury and fibrosis
- (2014) Ming-Yi Xu et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Vascular Endothelial Growth Factor Promotes Fibrosis Resolution and Repair in Mice
- (2014) Liu Yang et al. GASTROENTEROLOGY
- Effects of AG490 and S3I-201 on regulation of the JAK/STAT3 signaling pathway in relation to angiogenesis in TRAIL-resistant prostate cancer cells in vitro
- (2014) VENHAR GURBUZ et al. Oncology Letters
- STAT3-mediated attenuation of CCl4-induced mouse liver fibrosis by the protein kinase inhibitor sorafenib
- (2013) Yan-Ru Deng et al. JOURNAL OF AUTOIMMUNITY
- Erratum to “Clinical evidence for the regression of liver fibrosis” [J Hepatol 2012;56:1171–1180]
- (2013) Elizabeth L. Ellis et al. JOURNAL OF HEPATOLOGY
- Probiotic Yeast Inhibits VEGFR Signaling and Angiogenesis in Intestinal Inflammation
- (2013) Xinhua Chen et al. PLoS One
- Signal Transducer and Activator of Transcription 3 in Liver Diseases: A Novel Therapeutic Target
- (2012) Hua Wang et al. International Journal of Biological Sciences
- A histone deacetylase inhibitor, largazole, decreases liver fibrosis and angiogenesis by inhibiting transforming growth factor-β and vascular endothelial growth factor signalling
- (2012) Yuqing Liu et al. LIVER INTERNATIONAL
- Inhibition of PDGF, TGF-β, and Abl signaling and reduction of liver fibrosis by the small molecule Bcr-Abl tyrosine kinase antagonist Nilotinib
- (2011) Yuqing Liu et al. JOURNAL OF HEPATOLOGY
- Lack of Glycoprotein 130/Signal Transducer and Activator of Transcription 3-Mediated Signaling in Hepatocytes Enhances Chronic Liver Injury and Fibrosis Progression in a Model of Sclerosing Cholangitis
- (2010) Werner Plum et al. AMERICAN JOURNAL OF PATHOLOGY
- Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method
- (2010) T.-C. Chou CANCER RESEARCH
- Signal Transducer and Activator of Transcription 3 Protects From Liver Injury and Fibrosis in a Mouse Model of Sclerosing Cholangitis
- (2010) Markus Mair et al. GASTROENTEROLOGY
- Dissociation between liver inflammation and hepatocellular damage induced by carbon tetrachloride in myeloid cell-specific signal transducer and activator of transcription 3 gene knockout mice
- (2010) Norio Horiguchi et al. HEPATOLOGY
- New insights into the antifibrotic effects of sorafenib on hepatic stellate cells and liver fibrosis
- (2010) Yan Wang et al. JOURNAL OF HEPATOLOGY
- A novel STAT3 inhibitor, S3I-201, attenuates renal interstitial fibroblast activation and interstitial fibrosis in obstructive nephropathy
- (2010) Maoyin Pang et al. KIDNEY INTERNATIONAL
- Chemokines in Liver Inflammation and Fibrosis
- (2010) Hermann Wasmuth et al. SEMINARS IN LIVER DISEASE
- Apoptotic body engulfment by hepatic stellate cells promotes their survival by the JAK/STAT and Akt/NF-κB-dependent pathways
- (2009) Joy X. Jiang et al. JOURNAL OF HEPATOLOGY
- Therapeutic targeting of the PDGF and TGF-β-signaling pathways in hepatic stellate cells by PTK787/ZK22258
- (2009) Yuqing Liu et al. LABORATORY INVESTIGATION
- The STAT3 inhibitor NSC 74859 is effective in hepatocellular cancers with disrupted TGF-β signaling
- (2009) L Lin et al. ONCOGENE
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