Endothelin receptor B, a candidate gene from human studies at high altitude, improves cardiac tolerance to hypoxia in genetically engineered heterozygote mice

Protective effects of endothelin receptor A and B inhibitors against doxorubicin-induced cardiomyopathy

(2015) Matthias Schwebe et al.   BIOCHEMICAL PHARMACOLOGY

Whole genome sequencing of Ethiopian highlanders reveals conserved hypoxia tolerance genes

(2014) Nitin Udpa et al.   GENOME BIOLOGY

Whole-Genome Sequencing Uncovers the Genetic Basis of Chronic Mountain Sickness in Andean Highlanders

(2013) Dan Zhou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

MAPK and PI3K pathways regulate hypoxia-induced atrial natriuretic peptide secretion by controlling HIF-1 alpha expression in beating rabbit atria

(2013) Qiu-li Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Increased Sarcolipin Expression and Adrenergic Drive in Humans With Preserved Left Ventricular Ejection Fraction and Chronic Isolated Mitral Regurgitation

(2013) Junying Zheng et al.   Circulation-Heart Failure

Hypermethylation of EDNRB promoter contributes to the risk of colorectal cancer

(2013) Cheng Chen et al.   Diagnostic Pathology

Intracrine endothelin signaling evokes IP3-dependent increases in nucleoplasmic Ca2+ in adult cardiac myocytes

(2013) Clémence Merlen et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Involvement of AP-1 and C/EBPβ in Upregulation of Endothelin B (ETB) Receptor Expression in a Rodent Model of Glaucoma

(2013) Shaoqing He et al.   PLoS One

A Cell Permeable Peptide Targeting the Intracellular Loop 2 of Endothelin B Receptor Reduces Pulmonary Hypertension in a Hypoxic Rat Model

(2013) Daniel S. Green et al.   PLoS One

Abstract 4909: Calcitriol and arsenic trioxide synergistically inhibited proliferation of HL-60 cell line mainly through apoptosis pathway

(2012) Ji-Yeon Bae et al.   CANCER RESEARCH

Bosentan Reduces Pulmonary Artery Pressure in High Altitude Residents

(2012) Baktybek Kojonazarov et al.   HIGH ALTITUDE MEDICINE & BIOLOGY

Ouabain stimulates atrial natriuretic peptide secretion via the endothelin-1/ETB receptor-mediated pathway in beating rabbit atria

(2012) Li-ping Liu et al.   LIFE SCIENCES

Postnatal Ablation of Foxm1 from Cardiomyocytes Causes Late Onset Cardiac Hypertrophy and Fibrosis without Exacerbating Pressure Overload-Induced Cardiac Remodeling

(2012) Craig Bolte et al.   PLoS One

A methylation assay for the detection of non-muscle-invasive bladder cancer (NMIBC) recurrences in voided urine

(2011) Tahlita C.M. Zuiverloon et al.   BJU INTERNATIONAL

CD31, EDNRB and TSPAN7 are promising prognostic markers in clear-cell renal cell carcinoma revealed by genome-wide expression analyses of primary tumors and metastases

(2011) Daniela Wuttig et al.   INTERNATIONAL JOURNAL OF CANCER

Altitude, life expectancy and mortality from ischaemic heart disease, stroke, COPD and cancers: national population-based analysis of US counties

(2011) Majid Ezzati et al.   JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH

Experimental selection of hypoxia-tolerant Drosophila melanogaster

(2011) D. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The interdependence of endothelin-1 and calcium: a review

(2010) Nathan R. Tykocki et al.   CLINICAL SCIENCE

The GeneMANIA prediction server: biological network integration for gene prioritization and predicting gene function

(2010) David Warde-Farley et al.   NUCLEIC ACIDS RESEARCH

High-Altitude Medicine: Important for Trekkers and Mountaineers, Essential for Progress in Medicine

(2010) Yves Allemann et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Physiological Adaptation of the Cardiovascular System to High Altitude

(2010) Robert Naeije   PROGRESS IN CARDIOVASCULAR DISEASES

Genetic Evidence for High-Altitude Adaptation in Tibet

(2010) T. S. Simonson et al.   SCIENCE

Identifying Signatures of Natural Selection in Tibetan and Andean Populations Using Dense Genome Scan Data

(2010) Abigail Bigham et al.   PLoS Genetics

Increased expression of vascular endothelin type B and angiotensin type 1 receptors in patients with ischemic heart disease

(2009) Ivan Dimitrijevic et al.   BMC Cardiovascular Disorders

Bosentan Enhances Viral Load via Endothelin-1 Receptor Type-A–Mediated p38 Mitogen-Activated Protein Kinase Activation While Improving Cardiac Function During Coxsackievirus-Induced Myocarditis

(2009) David Marchant et al.   CIRCULATION RESEARCH

Endothelial ETB Limits Vascular Remodelling and Development of Pulmonary Hypertension during Hypoxia

(2009) N.F. Kelland et al.   JOURNAL OF VASCULAR RESEARCH

Targeting of endothelin receptor-B to the neural crest

(2008) Noah R. Druckenbrod et al.   GENESIS

Measurement of cardiac function using pressure–volume conductance catheter technique in mice and rats

(2008) Pál Pacher et al.   Nature Protocols

Adaptation and Mal-Adaptation to Ambient Hypoxia; Andean, Ethiopian and Himalayan Patterns

(2008) Guoqiang Xing et al.   PLoS One

Mechanisms Underlying Hypoxia Tolerance in Drosophila melanogaster: hairy as a Metabolic Switch

(2008) Dan Zhou et al.   PLoS Genetics