Applications of polymeric adjuvants in studying autoimmune responses and vaccination against infectious diseases

Polymeric Multilayer Capsule-Mediated Vaccination Induces Protective Immunity Against Cancer and Viral Infection

(2012) Bruno G. De Geest et al.   ACS Nano

Enhancement of Antibody-Induced Arthritis via Toll-Like Receptor 2 Stimulation Is Regulated by Granulocyte Reactive Oxygen Species

(2012) Tiina Kelkka et al.   AMERICAN JOURNAL OF PATHOLOGY

Transgene expression and local tissue distribution of naked and polymer-condensed plasmid DNA after intradermal administration in mice

(2012) R. Noelle Palumbo et al.   JOURNAL OF CONTROLLED RELEASE

The spectrum of ASIA: ‘Autoimmune (Auto-inflammatory) Syndrome induced by Adjuvants’

(2012) N Agmon-Levin et al.   LUPUS

Antigen-Displaying Lipid-Enveloped PLGA Nanoparticles as Delivery Agents for a Plasmodium vivax Malaria Vaccine

(2012) James J. Moon et al.   PLoS One

Polyanhydride microparticles enhance dendritic cell antigen presentation and activation

(2011) Maria P. Torres et al.   Acta Biomaterialia

Collagen Type II and a Thermo-Responsive Polymer of N-Isopropylacrylamide Induce Arthritis Independent of Toll-Like Receptors

(2011) Akhilesh Kumar Shakya et al.   AMERICAN JOURNAL OF PATHOLOGY

Poly(2-aminoethyl methacrylate) with Well-Defined Chain Length for DNA Vaccine Delivery to Dendritic Cells

(2011) Weihang Ji et al.   BIOMACROMOLECULES

Activation of innate immune responses in a pathogen-mimicking manner by amphiphilic polyanhydride nanoparticle adjuvants

(2011) Latrisha K. Petersen et al.   BIOMATERIALS

The induction of innate and adaptive immunity by biodegradable poly(γ-glutamic acid) nanoparticles via a TLR4 and MyD88 signaling pathway

(2011) Tomofumi Uto et al.   BIOMATERIALS

Enhancing immunogenicity to PLGA microparticulate systems by incorporation of alginate and RGD-modified alginate

(2011) Elena Mata et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Carbohydrate-based immune adjuvants

(2011) Nikolai Petrovsky et al.   Expert Review of Vaccines

Tumor eradication by immunotherapy with biodegradable PLGA microspheres-an alternative to incomplete Freund's adjuvant

(2011) Marc Mueller et al.   INTERNATIONAL JOURNAL OF CANCER

Comparison of humoral and cell-mediated immune responses to cationic PLGA microspheres containing recombinant hepatitis B antigen

(2011) Vinay Saini et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination

(2011) Rolf J. Verheul et al.   JOURNAL OF CONTROLLED RELEASE

Polyelectrolyte LbL microcapsules versus PLGA microparticles for immunization with a protein antigen

(2011) Marie-Luce De Temmerman et al.   JOURNAL OF CONTROLLED RELEASE

Adjuvant properties of a biocompatible thermo-responsive polymer of N-isopropylacrylamide in autoimmunity and arthritis

(2011) A. K. Shakya et al.   Journal of the Royal Society Interface

Chitosan Nanoparticles Act as an Adjuvant to Promote both Th1 and Th2 Immune Responses Induced by Ovalbumin in Mice

(2011) Zheng-Shun Wen et al.   Marine Drugs

Charged for success

(2011) Enrico Mastrobattista et al.   NATURE MATERIALS

Development of Effective Cancer Vaccine Using Targeting System of Antigen Protein to APCs

(2011) Tomoaki Kurosaki et al.   PHARMACEUTICAL RESEARCH

Polymersomes enhance the immunogenicity of influenza subunit vaccine

(2011) Christophe Barnier Quer et al.   Polymer Chemistry

Poly(methyl vinyl ether-co-maleic anhydride) nanoparticles as innate immune system activators

(2011) A.I. Camacho et al.   VACCINE

Preparation and immunological effectiveness of a swine influenza DNA vaccine encapsulated in chitosan nanoparticles

(2011) Kai Zhao et al.   VACCINE

Encapsulation into amphiphilic polyanhydride microparticles stabilizes Yersinia pestis antigens

(2010) Brenda Carrillo-Conde et al.   Acta Biomaterialia

Rabeximod reduces arthritis severity in mice by decreasing activation of inflammatory cells

(2010) M. Hultqvist et al.   ANNALS OF THE RHEUMATIC DISEASES

Delta inulin: a novel, immunologically active, stable packing structure comprising  -D-[2 -> 1] poly(fructo-furanosyl)  -D-glucose polymers

(2010) P. D. Cooper et al.   GLYCOBIOLOGY

Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome

(2010) C. Bauer et al.   GUT

Complement drives Th17 cell differentiation and triggers autoimmune arthritis

(2010) Motomu Hashimoto et al.   JOURNAL OF EXPERIMENTAL MEDICINE

An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous flaviviruses

(2010) M. Lobigs et al.   JOURNAL OF GENERAL VIROLOGY

Induction of mucosal and systemic antibody and T-cell responses following prime-boost immunization with novel adjuvanted human immunodeficiency virus-1-vaccine formulations

(2010) A. D. Cristillo et al.   JOURNAL OF GENERAL VIROLOGY

In Vitro Analysis of Acetalated Dextran Microparticles as a Potent Delivery Platform for Vaccine Adjuvants

(2010) Eric M. Bachelder et al.   MOLECULAR PHARMACEUTICS

Polymer nanoparticles containing tumor lysates as antigen delivery vehicles for dendritic cell–based antitumor immunotherapy

(2010) Shashi Prasad et al.   Nanomedicine-Nanotechnology Biology and Medicine

Efficacy of poly[di(sodium carboxylatophenoxy)phosphazene] (PCPP) as mucosal adjuvant to induce protective immunity against respiratory pathogens

(2010) Doo-Hee Shim et al.   VACCINE

Chitosan-based nanoparticles for improving immunization against hepatitis B infection

(2010) Cecilia Prego et al.   VACCINE

Nasal vaccination with N-trimethyl chitosan and PLGA based nanoparticles: Nanoparticle characteristics determine quality and strength of the antibody response in mice against the encapsulated antigen

(2010) Bram Slütter et al.   VACCINE

A Protective Vaccine Delivery System for In Vivo T Cell Stimulation Using Nanoengineered Polymer Hydrogel Capsules

(2009) Amy Sexton et al.   ACS Nano

Cytosolic Delivery Mediated via Electrostatic Surface Binding of Protein, Virus, or siRNA Cargos to pH-Responsive Core−Shell Gel Particles

(2009) Yuhua Hu et al.   BIOMACROMOLECULES

High Throughput Cell-Based Screening of Biodegradable Polyanhydride Libraries

(2009) Andrew Adler et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

TMC–MCC (N-trimethyl chitosan–mono-N-carboxymethyl chitosan) nanocomplexes for mucosal delivery of vaccines

(2009) Burcu Sayın et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Chitosan-based systems for the delivery of vaccine antigens

(2009) H. Çiğdem Arca et al.   Expert Review of Vaccines

The ABC of clinical and experimental adjuvants—A brief overview

(2009) Richard Brunner et al.   IMMUNOLOGY LETTERS

Biodegradable Polyelectrolyte Microcapsules: Antigen Delivery Tools with Th17 Skewing Activity after Pulmonary Delivery

(2009) Stefaan De Koker et al.   JOURNAL OF IMMUNOLOGY

Evaluation of properties of chitosan as an adjuvant for inactivated influenza vaccines administered parenterally

(2009) Yuri Ghendon et al.   JOURNAL OF MEDICAL VIROLOGY

In VivoStudies on the Effect of Co-Encapsulation of CpG DNA and Antigen in Acid-Degradable Microparticle Vaccines

(2009) Tristan T. Beaudette et al.   MOLECULAR PHARMACEUTICS

Development of Multi-Phase Emulsions Based on Bioresorbable Polymers and Oily Adjuvant

(2009) Ming-Hsi Huang et al.   PHARMACEUTICAL RESEARCH

Poly[di(carboxylatophenoxy)phosphazene] is a potent adjuvant for intradermal immunization

(2009) Alexander K. Andrianov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chronic fatigue syndrome with autoantibodies — The result of an augmented adjuvant effect of hepatitis-B vaccine and silicone implant

(2008) Agmon-Levin Nancy et al.   AUTOIMMUNITY REVIEWS

Immune response by nasal delivery of hepatitis B surface antigen and codelivery of a CpG ODN in alginate coated chitosan nanoparticles

(2008) Olga Borges et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Immunomodulatory biomaterials

(2008) Surya K. Mallapragada et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

PMMA particle-mediated DNA vaccine for cervical cancer

(2008) Pei-Jen Lou et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Surface coating of PLGA microparticles with protamine enhances their immunological performance through facilitated phagocytosis

(2008) Julia M. Martínez Gómez et al.   JOURNAL OF CONTROLLED RELEASE

Co-administration of polyphosphazenes with CpG oligodeoxynucleotides strongly enhances immune responses in mice immunized with Hepatitis B virus surface antigen

(2008) George Mutwiri et al.   VACCINE