Transcriptional coregulators: emerging roles of SRC family of coactivators in disease pathology

Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1

(2014) Y. Wang et al.   CANCER RESEARCH

Steroid Receptor Coactivator-3 Regulates Glucose Metabolism in Bladder Cancer Cells through Coactivation of Hypoxia Inducible Factor 1α

(2014) Wei Zhao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steroid Receptor Coactivator 1 is an Integrator of Glucose and NAD+/NADH Homeostasis

(2014) Massoud Motamed et al.   MOLECULAR ENDOCRINOLOGY

Identification of Verrucarin A as a Potent and Selective Steroid Receptor Coactivator-3 Small Molecule Inhibitor

(2014) Fei Yan et al.   PLoS One

SRC-2 Is an Essential Coactivator for Orchestrating Metabolism and Circadian Rhythm

(2014) Erin Stashi et al.   Cell Reports

Nuclear Receptor Coactivators: Master Regulators of Human Health and Disease

(2013) Subhamoy Dasgupta et al.   Annual Review of Medicine

PGC1α Expression Defines a Subset of Human Melanoma Tumors with Increased Mitochondrial Capacity and Resistance to Oxidative Stress

(2013) Francisca Vazquez et al.   CANCER CELL

Corticosteroid resistance in patients with asthma and chronic obstructive pulmonary disease

(2013) Peter J. Barnes   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Proteomic Analysis of Coregulators Bound to ERα on DNA and Nucleosomes Reveals Coregulator Dynamics

(2013) Charles E. Foulds et al.   MOLECULAR CELL

Research Resource: Tissue- and Pathway-Specific Metabolomic Profiles of the Steroid Receptor Coactivator (SRC) Family

(2013) Brian York et al.   MOLECULAR ENDOCRINOLOGY

Research Resource: Loss of the Steroid Receptor Coactivators Confers Neurobehavioral Consequences

(2013) Erin Stashi et al.   MOLECULAR ENDOCRINOLOGY

Epigenetic Mechanisms of Rubinstein–Taybi Syndrome

(2013) Elizabeth Park et al.   NEUROMOLECULAR MEDICINE

SRC-2 Coactivator Deficiency Decreases Functional Reserve in Response to Pressure Overload of Mouse Heart

(2013) Erin L. Reineke et al.   PLoS One

Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

(2013) C. Geng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal

(2013) J. Gao et al.   Science Signaling

Critical Components of the Pluripotency Network Are Targets for the p300/CBP Interacting Protein (p/CIP) in Embryonic Stem Cells

(2013) J.M. Chitilian et al.   STEM CELLS

Abstract 5153: Steroid receptor coactivator-2 mediates oncogenic reprogramming of cancer cell metabolism

(2012) Subhamoy Dasgupta et al.   CANCER RESEARCH

Ablation of Steroid Receptor Coactivator-3 Resembles the Human CACT Metabolic Myopathy

(2012) Brian York et al.   Cell Metabolism

Histone deacetylase complexes as caretakers of genome stability

(2012) Robert S. Lahue et al.   Epigenetics

Ncoa3 functions as an essential Esrrb coactivator to sustain embryonic stem cell self-renewal and reprogramming

(2012) M. Percharde et al.   GENES & DEVELOPMENT

Role of Nuclear Receptor Coactivator 3 (Ncoa3) in Pluripotency Maintenance

(2012) Zhaoting Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ERK3 signals through SRC-3 coactivator to promote human lung cancer cell invasion

(2012) Weiwen Long et al.   JOURNAL OF CLINICAL INVESTIGATION

Expression level of histone deacetylase 2 correlates with occurring of chronic obstructive pulmonary diseases

(2012) Yiqing Qu et al.   MOLECULAR BIOLOGY REPORTS

A new isoform of steroid receptor coactivator-1 is crucial for pathogenic progression of endometriosis

(2012) Sang Jun Han et al.   NATURE MEDICINE

Nuclear receptor coregulators: modulators of pathology and therapeutic targets

(2012) David M. Lonard et al.   Nature Reviews Endocrinology

The cBio Cancer Genomics Portal: An Open Platform for Exploring Multidimensional Cancer Genomics Data: Figure 1.

(2012) Ethan Cerami et al.   Cancer Discovery

Metastatic Progression with Resistance to Aromatase Inhibitors Is Driven by the Steroid Receptor Coactivator SRC-1

(2011) J. McBryan et al.   CANCER RESEARCH

Steroid Receptor Coactivator-1 Upregulates Integrin  5 Expression to Promote Breast Cancer Cell Adhesion and Migration

(2011) L. Qin et al.   CANCER RESEARCH

Analysis of the Human Endogenous Coregulator Complexome

(2011) Anna Malovannaya et al.   CELL

Crosstalk between Components of Circadian and Metabolic Cycles in Mammals

(2011) Gad Asher et al.   Cell Metabolism

Cellular Energy Depletion Resets Whole-Body Energy by Promoting Coactivator-Mediated Dietary Fuel Absorption

(2011) Atul R. Chopra et al.   Cell Metabolism

Glucocorticoid-Dependent Phosphorylation of the Transcriptional Coregulator GRIP1

(2011) J. Dobrovolna et al.   MOLECULAR AND CELLULAR BIOLOGY

Cullin 3 mediates SRC-3 ubiquitination and degradation to control the retinoic acid response

(2011) C. Ferry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

The Coactivator SRC-1 Is an Essential Coordinator of Hepatic Glucose Production

(2010) Jean-Francois Louet et al.   Cell Metabolism

Preferential Oxidation of Triacylglyceride-Derived Fatty Acids in Heart Is Augmented by the Nuclear Receptor PPARα

(2010) Natasha H. Banke et al.   CIRCULATION RESEARCH

PGC-1 Coactivators in Cardiac Development and Disease

(2010) Glenn C. Rowe et al.   CIRCULATION RESEARCH

Steroid Receptor Coactivator (SRC) Family: Masters of Systems Biology

(2010) Brian York et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SRC-3Δ4 Mediates the Interaction of EGFR with FAK to Promote Cell Migration

(2010) Weiwen Long et al.   MOLECULAR CELL

Streamlined analysis schema for high-throughput identification of endogenous protein complexes

(2010) A. Malovannaya et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Transcriptional Control of Mitochondrial Biogenesis and Function

(2009) M. Benjamin Hock et al.   Annual Review of Physiology

The Steroid Receptor Coactivator-1 Regulates Twist Expression and Promotes Breast Cancer Metastasis

(2009) L. Qin et al.   CANCER RESEARCH

Impaired PGC-1α function in muscle in Huntington's disease

(2009) Rajnish K. Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Epigenetic mechanisms in neurological diseases: genes, syndromes, and therapies

(2009) Rocio G Urdinguio et al.   LANCET NEUROLOGY

Mutations in the chromatin-associated protein ATRX

(2008) Richard J. Gibbons et al.   HUMAN MUTATION

Essential Phosphatases and a Phospho-Degron Are Critical for Regulation of SRC-3/AIB1 Coactivator Function and Turnover

(2008) Chao Li et al.   MOLECULAR CELL

Atypical Protein Kinase C Regulates Dual Pathways for Degradation of the Oncogenic Coactivator SRC-3/AIB1

(2008) Ping Yi et al.   MOLECULAR CELL

HIF-independent regulation of VEGF and angiogenesis by the transcriptional coactivator PGC-1α

(2008) Zoltan Arany et al.   NATURE

Absence of the SRC-2 Coactivator Results in a Glycogenopathy Resembling Von Gierke's Disease

(2008) A. R. Chopra et al.   SCIENCE

Multi-modulation of nuclear receptor coactivators through posttranslational modifications

(2008) Sang Jun Han et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM