Phospholipase A2structure/function, mechanism, and signaling

Age-Related Changes in Bone Morphology Are Accelerated in Group VIA Phospholipase A2 (iPLA2β)-Null Mice

(2008) Sasanka Ramanadham et al.   AMERICAN JOURNAL OF PATHOLOGY

Biochemistry and Physiology of Mammalian Secreted Phospholipases A2

(2008) Gérard Lambeau et al.   Annual Review of Biochemistry

Interaction of Group IA Phospholipase A2with Metal Ions and Phospholipid Vesicles Probed with Deuterium Exchange Mass Spectrometry†

(2008) John E. Burke et al.   BIOCHEMISTRY

Intracellular phospholipase A2 group IVA and group VIA play important roles in Wallerian degeneration and axon regeneration after peripheral nerve injury

(2008) Rubèn López-Vales et al.   BRAIN

Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque

(2008) Patrick W. Serruys et al.   CIRCULATION

Role of lipoprotein-associated phospholipase A2 in atherosclerosis

(2008) Shahar Lavi et al.   Current Atherosclerosis Reports

A Phospholipid Substrate Molecule Residing in the Membrane Surface Mediates Opening of the Lid Region in Group IVA Cytosolic Phospholipase A2

(2008) John E. Burke et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Calcium Binding Rigidifies the C2 Domain and the Intradomain Interaction of GIVA Phospholipase A2as Revealed by Hydrogen/Deuterium Exchange Mass Spectrometry

(2008) Yuan-Hao Hsu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pro-inflammatory Secretory Phospholipase A2 Type IIA Binds to Integrins αvβ3 and α4β1 and Induces Proliferation of Monocytic Cells in an Integrin-dependent Manner

(2008) Jun Saegusa et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Domain That Mediates Association of Platelet-activating Factor Acetylhydrolase with High Density Lipoprotein

(2008) Alison A. Gardner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

iPLA2β: front and center in human monocyte chemotaxis to MCP-1

(2008) Ravi S. Mishra et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Indole Cytosolic Phospholipase A2α Inhibitors: Discovery and in Vitro and in Vivo Characterization of 4-{3-[5-Chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic Acid, Efipladib

(2008) John C. McKew et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis of Polyfluoro Ketones for Selective Inhibition of Human Phospholipase A2Enzymes

(2008) Constantinos Baskakis et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent

(2008) Emile R. Mohler et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development

(2008) Robert L Wilensky et al.   NATURE MEDICINE