Exploring the pathophysiology behind the more common genetic and acquired lipodystrophies

The Werner syndrome protein: linking the replication checkpoint response to genome stability

(2016) Pietro Pichierri et al.   Aging-US

Seipin differentially regulates lipogenesis and adipogenesis through a conserved core sequence and an evolutionarily acquired C-terminus

(2013) Wulin Yang et al.   BIOCHEMICAL JOURNAL

HIV Protease Inhibitors Disrupt Lipid Metabolism by Activating Endoplasmic Reticulum Stress and Inhibiting Autophagy Activity in Adipocytes

(2013) Beth S. Zha et al.   PLoS One

The protease inhibitor atazanavir triggers autophagy and mitophagy in human preadipocytes

(2012) Lara Gibellini et al.   AIDS

Alterations in Lipid Signaling Underlie Lipodystrophy Secondary to AGPAT2 Mutations

(2012) A. R. Subauste et al.   DIABETES

Adipocyte Maturation Arrest: A Determinant of Systemic Insulin Resistance to Glucose Disposal

(2012) Nicola Abate   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Seipin: from human disease to molecular mechanism

(2012) Bethany R. Cartwright et al.   JOURNAL OF LIPID RESEARCH

RECQL5 plays co-operative and complementary roles with WRN syndrome helicase

(2012) Venkateswarlu Popuri et al.   NUCLEIC ACIDS RESEARCH

Lipodystrophies: Genetic and Acquired Body Fat Disorders

(2011) Abhimanyu Garg   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Perilipin Deficiency and Autosomal Dominant Partial Lipodystrophy

(2011) Sheetal Gandotra et al.   NEW ENGLAND JOURNAL OF MEDICINE

Congenital generalized lipodystrophy, type 4 (CGL4) associated with myopathy due to novel PTRF mutations

(2010) Savitha Shastry et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Krüppel-like factor KLF9 regulates PPARγ transactivation at the middle stage of adipogenesis

(2010) H Pei et al.   CELL DEATH AND DIFFERENTIATION

Inhibition of mitochondrial function by efavirenz increases lipid content in hepatic cells

(2010) Ana Blas-García et al.   HEPATOLOGY

Lipodystrophy: pathophysiology and advances in treatment

(2010) Christina G. Fiorenza et al.   Nature Reviews Endocrinology

Fatal Cardiac Arrhythmia and Long-QT Syndrome in a New Form of Congenital Generalized Lipodystrophy with Muscle Rippling (CGL4) Due to PTRF-CAVIN Mutations

(2010) Anna Rajab et al.   PLoS Genetics

Genetic analysis implicates resistin in HIV lipodystrophy

(2009) Koustubh Ranade et al.   AIDS

Zidovudine/lamivudine contributes to insulin resistance within 3 months of starting combination antiretroviral therapy

(2009) Regje ME Blümer et al.   AIDS

Metabolic outcomes in a randomized trial of nucleoside, nonnucleoside and protease inhibitor-sparing regimens for initial HIV treatment

(2009) Richard H Haubrich et al.   AIDS

Lipodystrophies: Disorders of adipose tissue biology

(2009) Abhimanyu Garg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Drug-induced lipotoxicity: Lipodystrophy associated with HIV-1 infection and antiretroviral treatment

(2009) Francesc Villarroya et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Overlapping syndrome with familial partial lipodystrophy, Dunnigan variety and cardiomyopathy due to amino-terminal heterozygous missense lamin A/C mutations

(2009) L Subramanyam et al.   CLINICAL GENETICS

Partial lipodystrophy and insulin resistant diabetes in a patient with a homozygous nonsense mutation inCIDEC

(2009) Oscar Rubio-Cabezas et al.   EMBO Molecular Medicine

The Effect of Individual Antiretroviral Drugs on Body Composition in HIV-Infected Persons Initiating Highly Active Antiretroviral Therapy

(2009) Judith C Shlay et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Human PTRF mutations cause secondary deficiency of caveolins resulting in muscular dystrophy with generalized lipodystrophy

(2009) Yukiko K. Hayashi et al.   JOURNAL OF CLINICAL INVESTIGATION

Gene Expression and Immunohistochemistry in Adipose Tissue of HIV Type 1–Infected Patients with Nucleoside Analogue Reverse‐Transcriptase Inhibitor–Associated Lipoatrophy

(2009) M. Sievers et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical and translational implications of the caveolin gene family: lessons from mouse models and human genetic disorders

(2009) Isabelle Mercier et al.   LABORATORY INVESTIGATION

Long term adverse effects related to nucleoside reverse transcriptase inhibitors: Clinical impact of mitochondrial toxicity

(2009) Anne Maagaard et al.   SCANDINAVIAN JOURNAL OF INFECTIOUS DISEASES

Novel LMNA Gene Mutation in a Patient With Atypical Werner's Syndrome

(2009) Yun Jeong Doh et al.   KOREAN JOURNAL OF INTERNAL MEDICINE

Adipose tissue inflammation and liver fat in patients with highly active antiretroviral therapy-associated lipodystrophy

(2008) Ksenia Sevastianova et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

HIV-protease inhibitors block the enzymatic activity of purified Ste24p

(2008) Sarah E. Hudon et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Triglyceride containing lipid droplets and lipid droplet-associated proteins

(2008) Sven-Olof Olofsson et al.   CURRENT OPINION IN LIPIDOLOGY

The Human Lipodystrophy Gene BSCL2/Seipin May Be Essential for Normal Adipocyte Differentiation

(2008) V. A. Payne et al.   DIABETES

HIV-associated lipodystrophy: a review of underlying mechanisms and therapeutic options

(2008) J. E. Mallewa et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Fertility and Obstetrical Complications in Women withLMNA-Related Familial Partial Lipodystrophy

(2008) M. C. Vantyghem et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association of a Homozygous Nonsense Caveolin-1 Mutation with Berardinelli-Seip Congenital Lipodystrophy

(2008) C. A. Kim et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Complement Abnormalities in Acquired Lipodystrophy Revisited

(2008) David B. Savage et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Acquired partial lipodystrophy in an 11-year-old girl

(2008) Joanna Oswiecimska et al.   PEDIATRICS INTERNATIONAL

Human Immunodeficiency Virus (HIV)-1 Viral Protein R Suppresses Transcriptional Activity of Peroxisome Proliferator-Activated Receptor γ and Inhibits Adipocyte Differentiation: Implications for HIV-Associated Lipodystrophy

(2007) Shashi Shrivastav et al.   MOLECULAR ENDOCRINOLOGY