Trifluoromethanesulfonyloxy-group-directed regioselective (3 + 2) cycloadditions of benzynes for the synthesis of functionalized benzo-fused heterocycles

The Hexadehydro-Diels-Alder Reaction: A New Chapter in Aryne Chemistry

(2014) Catherine Holden née Hall et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enabling the Use of Heterocyclic Arynes in Chemical Synthesis

(2014) Adam E. Goetz et al.   JOURNAL OF ORGANIC CHEMISTRY

Synchronous ArF and ArSn Bond Formation through Fluorostannylation of Arynes

(2013) Hiroto Yoshida et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A “Hot, Energized” Benzyne

(2013) Reinhard W. Hoffmann et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Regiocomplementary Cycloaddition Reactions of Boryl- and Silylbenzynes with 1,3-Dipoles: Selective Synthesis of Benzo-Fused Azole Derivatives

(2013) Takashi Ikawa et al.   JOURNAL OF ORGANIC CHEMISTRY

ortho-Selective nucleophilic addition of amines to 3-borylbenzynes: synthesis of multisubstituted anilines by the triple role of the boryl group

(2013) Akira Takagi et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Generation of 3-borylbenzynes, their regioselective Diels–Alder reactions, and theoretical analysis

(2013) Akira Takagi et al.   TETRAHEDRON

Solution-Phase Synthesis of a Diverse Library of Benzisoxazoles Utilizing the [3 + 2] Cycloaddition of in Situ-Generated Nitrile Oxides and Arynes

(2013) Anton V. Dubrovskiy et al.   ACS Combinatorial Science

A Closer Look at Aryne Chemistry: Details that Remain Mysterious

(2013) Chunrui Wu et al.   Asian Journal of Organic Chemistry

A Comprehensive History of Arynes in Natural Product Total Synthesis

(2012) Pamela M. Tadross et al.   CHEMICAL REVIEWS

Synthesis of Benzisoxazolines by the Coupling of Arynes with Nitrones

(2012) Chun Lu et al.   JOURNAL OF ORGANIC CHEMISTRY

Experimental and Theoretical Studies on Regiocontrol of Benzyne Reactions Using Silyl and Boryl Directing Groups

(2012) Takashi Ikawa et al.   JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN

Steric Effects Compete with Aryne Distortion To Control Regioselectivities of Nucleophilic Additions to 3-Silylarynes

(2012) Sarah M. Bronner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Regioselective reactions of 3,4-pyridynes enabled by the aryne distortion model

(2012) Adam E. Goetz et al.   Nature Chemistry

Use of benzynes for the synthesis of heterocycles

(2012) Anton V. Dubrovskiy et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cine Substitution of Arenes Using the Aryl Carbamate as a Removable Directing Group

(2012) Tehetena Mesganaw et al.   ORGANIC LETTERS

Nickel-Catalyzed Amination of Aryl Sulfamates

(2011) Stephen D. Ramgren et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Discovery of Orally Active, Potent, and Selective Benzotriazole-Based PTP1B Inhibitors

(2011) Dipam Patel et al.   ChemMedChem

Pd-catalyzed Reactions Involving Arynes

(2011) S. A. Worlikar et al.   CURRENT ORGANIC CHEMISTRY

Synthesis of a Focused Chemical Library Based on Derivatives of Embelin, a Natural Product with Proapoptotic and Anticancer Properties

(2011) Guillaume Viault et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 2H-Indazoles by the [3 + 2] Dipolar Cycloaddition of Sydnones with Arynes

(2011) Yuesi Fang et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis of 3-Substituted Indazoles from Arynes andN-Tosylhydrazones

(2011) Pan Li et al.   ORGANIC LETTERS

Selective, Nickel-Catalyzed Hydrogenolysis of Aryl Ethers

(2011) A. G. Sergeev et al.   SCIENCE

Insertion of arynes into the carbon–oxygen double bond of amides and its application into the sequential reactions

(2011) Eito Yoshioka et al.   TETRAHEDRON

Conventional and microwave assisted synthesis of 2-oxo-4-substituted aryl-azetidine derivatives of benzotriazole: A new class of biological compounds

(2010) Adesh Dubey et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Aryne,ortho-Quinone Methide, andortho-Quinodimethane: Synthesis of Multisubstituted Arenes Using the Aromatic Reactive Intermediates

(2010) Hiroto Yoshida et al.   BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN

An alkynylboronate cycloaddition strategy to functionalised benzyne derivatives

(2010) James D. Kirkham et al.   CHEMICAL COMMUNICATIONS

Indolyne and Aryne Distortions and Nucleophilic Regioselectivites

(2010) Paul H.-Y. Cheong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Indolyne Experimental and Computational Studies: Synthetic Applications and Origins of Selectivities of Nucleophilic Additions

(2010) G-Yoon J. Im et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An efficient entry to 1,2-benzisoxazoles via 1,3-dipolar cycloaddition of in situ generated nitrile oxides and benzyne

(2010) Christian Spiteri et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of Benzisoxazoles by the [3 + 2] Cycloaddition ofin situGenerated Nitrile Oxides and Arynes

(2010) Anton V. Dubrovskiy et al.   ORGANIC LETTERS

New Synthesis of 1-Substituted-1H-indazoles via 1,3-Dipolar Cycloaddition ofin situGenerated Nitrile Imines and Benzyne

(2010) Christian Spiteri et al.   ORGANIC LETTERS

Cycloaddition of benzynes and nitrile oxides: synthesis of benzisoxazoles

(2010) James A. Crossley et al.   TETRAHEDRON LETTERS

Novel Non-Peptide Nociceptin/Orphanin FQ Receptor Agonist, 1-[1-(1-Methylcyclooctyl)-4-piperidinyl]-2-[(3R)-3-piperidinyl]-1H-benzimidazole: Design, Synthesis, and Structure−Activity Relationship of Oral Receptor Occupancy in the Brain for Orally Potent Antianxiety Drug(1, 2)

(2009) Shigeo Hayashi et al.   JOURNAL OF MEDICINAL CHEMISTRY

Benzyne Click Chemistry with in Situ Generated Aromatic Azides

(2009) Fengzhi Zhang et al.   ORGANIC LETTERS

RECENT APPLICATIONS OF ARYNE CHEMISTRY TO ORGANIC SYNTHESIS. A REVIEW

(2009) Roberto Sanz   ORGANIC PREPARATIONS AND PROCEDURES INTERNATIONAL

Design, synthesis, and antifungal activity of triazole and benzotriazole derivatives

(2008) Zahra Rezaei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Copper-free ‘click’: 1,3-dipolar cycloaddition of azides and arynes

(2008) Lachlan Campbell-Verduyn et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides

(2008) Feng Shi et al.   ORGANIC LETTERS

A novel α,β-unsaturated nitrone-aryne [3+2] cycloaddition and its application in the synthesis of the cortistatin core

(2008) Mingji Dai et al.   TETRAHEDRON LETTERS

Synthesis of Indazoles by the [3+2] Cycloaddition of Diazo Compounds with Arynes and Subsequent Acyl Migration

(2007) Zhijian Liu et al.   JOURNAL OF ORGANIC CHEMISTRY