标题
STAT inhibitors for cancer therapy
作者
关键词
Curcumin, Mipomersen, Decoy Oligonucleotide, Renal Cancer Cell Line, Hormone Refractory Prostate Cancer Cell
出版物
Journal of Hematology & Oncology
Volume 6, Issue 1, Pages 90
出版商
Springer Nature
发表日期
2013-12-05
DOI
10.1186/1756-8722-6-90
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Adding a new facet to STAT5 in CML: Multitasking for leukemic cells
- (2013) Wolfgang Warsch et al. CELL CYCLE
- Discovery of Novel STAT3 Small Molecule Inhibitors via in Silico Site-Directed Fragment-Based Drug Design
- (2013) Wenying Yu et al. JOURNAL OF MEDICINAL CHEMISTRY
- Therapeutic Roles of Curcumin: Lessons Learned from Clinical Trials
- (2012) Subash C. Gupta et al. AAPS Journal
- Repression of STAT3, STAT5A, and STAT5B expressions in chronic myelogenous leukemia cell line K–562 with unmodified or chemically modified siRNAs and induction of apoptosis
- (2012) Burçin Tezcanlı Kaymaz et al. ANNALS OF HEMATOLOGY
- Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
- (2012) Panagis Filippakopoulos et al. CELL
- Revisiting the Specificity of Small Molecule Inhibitors: The Example of Stattic in Dendritic Cells
- (2012) Isabella Sanseverino et al. CHEMISTRY & BIOLOGY
- Apolipoprotein B Synthesis Inhibition With Mipomersen in Heterozygous Familial Hypercholesterolemia
- (2012) Evan A. Stein et al. CIRCULATION
- Recent advances and novel agents for gastrointestinal stromal tumor (GIST)
- (2012) Gurpreet Lamba et al. Journal of Hematology & Oncology
- Therapeutic advancement of chronic lymphocytic leukemia
- (2012) Kang Lu et al. Journal of Hematology & Oncology
- Splenomegaly in myelofibrosis—new options for therapy and the therapeutic potential of Janus kinase 2 inhibitors
- (2012) Jasleen Randhawa et al. Journal of Hematology & Oncology
- Current management and novel agents for malignant melanoma
- (2012) Byung Lee et al. Journal of Hematology & Oncology
- Opposite regulation by PI3K/Akt and MAPK/ERK pathways of tissue factor expression, cell-associated procoagulant activity and invasiveness in MDA-MB-231 cells
- (2012) Chaoquan Hu et al. Journal of Hematology & Oncology
- Novel CD20 monoclonal antibodies for lymphoma therapy
- (2012) Shundong Cang et al. Journal of Hematology & Oncology
- Targeted drug delivery for cancer therapy: the other side of antibodies
- (2012) Michael A Firer et al. Journal of Hematology & Oncology
- Expression of miR-34 is lost in colon cancer which can be re-expressed by a novel agent CDF
- (2012) Sanchita Roy et al. Journal of Hematology & Oncology
- A STAT3-inhibitory hairpin decoy oligodeoxynucleotide discriminates between STAT1 and STAT3 and induces death in a human colon carcinoma cell line
- (2012) Inès Souissi et al. Molecular Cancer
- Structurally Modified Curcumin Analogs Inhibit STAT3 Phosphorylation and Promote Apoptosis of Human Renal Cell Carcinoma and Melanoma Cell Lines
- (2012) Matthew A. Bill et al. PLoS One
- XZH-5 Inhibits STAT3 Phosphorylation and Enhances the Cytotoxicity of Chemotherapeutic Drugs in Human Breast and Pancreatic Cancer Cells
- (2012) Aiguo Liu et al. PLoS One
- Randomized, Placebo-Controlled Trial of Mipomersen in Patients with Severe Hypercholesterolemia Receiving Maximally Tolerated Lipid-Lowering Therapy
- (2012) Mary P. McGowan et al. PLoS One
- Humanized Lewis-Y Specific Antibody Based Delivery ofSTAT3siRNA
- (2011) Yuelong Ma et al. ACS Chemical Biology
- XZH-5 inhibits STAT3 phosphorylation and causes apoptosis in human hepatocellular carcinoma cells
- (2011) Yan Liu et al. APOPTOSIS
- Sensitization of Head and Neck Cancer to Cisplatin Through the Use of a Novel Curcumin Analog
- (2011) Waleed M. Abuzeid et al. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
- Identification of a non-phosphorylated, cell permeable, small molecule ligand for the Stat3 SH2 domain
- (2011) Brent D.G. Page et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor
- (2011) M. S. Redell et al. BLOOD
- A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB
- (2011) Inès Souissi et al. BMC CELL BIOLOGY
- Novel small molecule, XZH-5, inhibits constitutive and interleukin-6-induced STAT3 phosphorylation in human rhabdomyosarcoma cells
- (2011) Aiguo Liu et al. CANCER SCIENCE
- STAT-3 Inhibitors: State of the Art and New Horizons for Cancer Treatment
- (2011) A. Lavecchia et al. CURRENT MEDICINAL CHEMISTRY
- A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells
- (2011) Li Lin et al. INTERNATIONAL JOURNAL OF CANCER
- Small molecules, LLL12 and FLLL32, inhibit STAT3 and exhibit potent growth suppressive activity in osteosarcoma cells and tumor growth in mice
- (2011) Grace-Ifeyinwa Onimoe et al. INVESTIGATIONAL NEW DRUGS
- Small Molecule STAT5-SH2 Domain Inhibitors Exhibit Potent Antileukemia Activity
- (2011) Brent D. G. Page et al. JOURNAL OF MEDICINAL CHEMISTRY
- The Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Induces Apoptosis in Medulloblastoma and Glioblastoma Cells
- (2011) Sarah Ball et al. PLoS One
- Combined treatment targeting HIF-1α and Stat3 is a potent strategy for prostate cancer therapy
- (2011) Kavitha Ramasamy Reddy et al. PROSTATE
- A novel small-molecule disrupts Stat3 SH2 domain–phosphotyrosine interactions and Stat3-dependent tumor processes
- (2010) Xiaolei Zhang et al. BIOCHEMICAL PHARMACOLOGY
- Novel STAT3 Phosphorylation Inhibitors Exhibit Potent Growth-Suppressive Activity in Pancreatic and Breast Cancer Cells
- (2010) L. Lin et al. CANCER RESEARCH
- IL-6, a risk factor for hepatocellular carcinoma: FLLL32 inhibits IL-6-Induced STAT3 phosphorylation in human hepatocellular cancer cells
- (2010) Yan Liu et al. CELL CYCLE
- Targeted Blockage of Signal Transducer and Activator of Transcription 5 Signaling Pathway with Decoy Oligodeoxynucleotides Suppresses Leukemic K562 Cell Growth
- (2010) Xiaozhong Wang et al. DNA AND CELL BIOLOGY
- A novel small molecule inhibits STAT3 phosphorylation and DNA binding activity and exhibits potent growth suppressive activity in human cancer cells
- (2010) Li Lin et al. Molecular Cancer
- Structure-Based Design of Conformationally Constrained, Cell-Permeable STAT3 Inhibitors
- (2010) Jianyong Chen et al. ACS Medicinal Chemistry Letters
- siRNA vs. shRNA: Similarities and differences
- (2009) Donald D. Rao et al. ADVANCED DRUG DELIVERY REVIEWS
- Design, synthesis, and evaluation of peptidomimetics containing Freidinger lactams as STAT3 inhibitors
- (2009) Cindy Gomez et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model
- (2009) B Fuh et al. BRITISH JOURNAL OF CANCER
- LLL-3, a STAT3 inhibitor, represses BCR-ABL-positive cell proliferation, activates apoptosis and improves the effects of Imatinib mesylate
- (2009) Andre Luiz Mencalha et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- New curcumin analogues exhibit enhanced growth-suppressive activity and inhibit AKT and signal transducer and activator of transcription 3 phosphorylation in breast and prostate cancer cells
- (2009) Li Lin et al. CANCER SCIENCE
- Disruption of Transcriptionally Active Stat3 Dimers with Non-phosphorylated, Salicylic Acid-Based Small Molecules: Potent in vitro and Tumor Cell Activities
- (2009) Steven Fletcher et al. CHEMBIOCHEM
- Conformationally Constrained Peptidomimetic Inhibitors of Signal Transducer and Activator of Transcription 3: Evaluation and Molecular Modeling
- (2009) Pijus K. Mandal et al. JOURNAL OF MEDICINAL CHEMISTRY
- Chemical Probes that Competitively and Selectively Inhibit Stat3 Activation
- (2009) Xuejun Xu et al. PLoS One
- A high-throughput assay for signal transducer and activator of transcription 5b based on fluorescence polarization
- (2008) Judith Müller et al. ANALYTICAL BIOCHEMISTRY
- Lack of toxicity of a STAT3 decoy oligonucleotide
- (2008) Malabika Sen et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Cryptotanshinone Inhibits Constitutive Signal Transducer and Activator of Transcription 3 Function through Blocking the Dimerization in DU145 Prostate Cancer Cells
- (2008) D.-S. Shin et al. CANCER RESEARCH
- Discovery of Chromone-Based Inhibitors of the Transcription Factor STAT5
- (2008) Judith Müller et al. CHEMBIOCHEM
- Blockage of the STAT3 signaling pathway with a decoy oligonucleotide suppresses growth of human malignant glioma cells
- (2008) Jinhai Gu et al. JOURNAL OF NEURO-ONCOLOGY
- T40214/PEI complex: A potent therapeutics for prostate cancer that targets STAT3 signaling
- (2008) Priya Weerasinghe et al. PROSTATE
- Galiellalactone is a novel therapeutic candidate against hormone-refractory prostate cancer expressing activated Stat3
- (2007) Rebecka Hellsten et al. PROSTATE
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