A small molecule, LLL12 inhibits constitutive STAT3 and IL-6-induced STAT3 signaling and exhibits potent growth suppressive activity in human multiple myeloma cells

A Novel Small Molecule, LLL12, Inhibits STAT3 Phosphorylation and Activities and Exhibits Potent Growth-Suppressive Activity in Human Cancer Cells

(2015) Li Lin et al.   NEOPLASIA

LLL-3 inhibits STAT3 activity, suppresses glioblastoma cell growth and prolongs survival in a mouse glioblastoma model

(2009) B Fuh et al.   BRITISH JOURNAL OF CANCER

 1 Integrin Adhesion Enhances IL-6-Mediated STAT3 Signaling in Myeloma Cells: Implications for Microenvironment Influence on Tumor Survival and Proliferation

(2009) K. H. Shain et al.   CANCER RESEARCH

Curcumin induces proapoptotic effects against human melanoma cells and modulates the cellular response to immunotherapeutic cytokines

(2009) M. A. Bill et al.   MOLECULAR CANCER THERAPEUTICS

Cancer Statistics, 2008

(2008) A. Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Targeting STAT3 in cancer: how successful are we?

(2008) Peibin Yue et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Inhibition of the mevalonate pathway potentiates the effects of lenalidomide in myeloma

(2008) Ellen van der Spek et al.   LEUKEMIA RESEARCH

Curcumin in combination with bortezomib synergistically induced apoptosis in human multiple myeloma U266 cells

(2008) Juwon Park et al.   Molecular Oncology

Design, synthesis, and studies of small molecule STAT3 inhibitors

(2007) Deepak Bhasin et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS