Review
Integrative & Complementary Medicine
Lichuang Huang, Qiang Lyu, Wanying Zheng, Qiao Yang, Gang Cao
Summary: Eucommia ulmoides Oliv. as a Traditional Chinese Medicine has been used for treating various diseases since ancient times, and modern pharmacological research has shown its therapeutic effects on conditions such as hypertension, diabetes, Parkinson's disease, and its antioxidant, anti-inflammatory, and anti-cancer activities.
Article
Chemistry, Medicinal
Ruo-yan Yang, Kun Liu, Jian-ying Wang, Lei Zhang, Bao-jun Zhang, Ying Yuan
Summary: This study quantified the active constituents of Eucommia ulmoides Oliv. bark and characterized their metabolic profiles. It also evaluated the anti-rheumatoid arthritis effects of certain compounds using in vitro cellular assays. The results provide insights into the pharmacological activity and potential mechanisms of Eucommia ulmoides Oliv.
Article
Horticulture
Xi Wu, Degang Zhao
Summary: Eucommia ulmoides Oliver, a traditional Chinese medicinal herb, contains a temperature-induced lipocalin gene (EuTIL1) that plays a role in the cold-stress response and enhances cold tolerance in plants. This discovery provides a potential molecular basis for the study of Eucommia ulmoides introduction and serves as a candidate gene for evaluating cold-tolerant plants.
Article
Chemistry, Multidisciplinary
Xin Dong, Jie Liu, Shu Guo, Fan Yang, Ren Bu, Jingkun Lu, Peifeng Xue
Summary: Eucommia ulmoides is an herb with various pharmacological activities. The bark and leaves of Eucommia ulmoides have different chemical compositions but can both improve bone metabolism and microarchitecture. The study suggests that Eucommia ulmoides leaves can be a potential alternative medical option when Eucommia ulmoides resources are scarce.
ARABIAN JOURNAL OF CHEMISTRY
(2022)
Article
Food Science & Technology
Zhenzhen Ge, Yuanyuan Zhang, Xueyuan Jin, Weijing Wang, Xiaoyuan Wang, Mengpei Liu, Lihua Zhang, Wei Zong
Summary: Dynamic high-pressure microfluidization can increase the alpha-helix to beta-sheet ratio of Eucommia ulmoides seed meal proteins, enhance bioavailability, significantly reduce particle size and zeta potential, improve solubility, enhance water holding capacity and fat absorption capability, and enhance emulsifying capability, showing promising potential for modifying the functional characteristics of the proteins.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Biochemistry & Molecular Biology
Rui Han, Tian Yuan, Zhi Yang, Qiang Zhang, Wei-Wei Wang, Li-Bin Lin, Ming-Qiang Zhu, Jin-Ming Gao
Summary: The study isolated 13 anti-neuroinflammatory compounds from Eucommia ulmoides Oliv. leaves, with ulmoidol significantly alleviating neuroinflammatory responses in microglia by inhibiting multiple signaling pathways. These results suggest that ulmoidol may have therapeutic potential for treating neuroinflammation-related neurodegenerative diseases.
BIOORGANIC CHEMISTRY
(2021)
Article
Pharmacology & Pharmacy
Shimaa M. A. Sayed, Karsten Siems, Christian Schmitz-Linneweber, Walter Luyten, Nadine Saul
Summary: This study investigated the effects of Eucommia ulmoides and Cuscuta chinensis extracts on healthspan parameters using the nematode Caenorhabditis elegans. The results showed that E. ulmoides improved physiological fitness, while C. chinensis acted as an overall healthspan enhancer with anti-aging properties and improved physical fitness in the nematodes.
FRONTIERS IN PHARMACOLOGY
(2021)
Article
Forestry
Shiming Deng, Zhijun Deng, Xiaofeng Wang, Hai Lu, Hua Xue
Summary: This study investigated the seed dormancy of Eucommia ulmoides Oliv., identifying the types of dormancy present and effective treatment methods. The findings contribute to the understanding and utilization of E. ulmoides germplasm resources in breeding and genetic improvement efforts.
Article
Chemistry, Multidisciplinary
Yingxia Lu, Xuan Dong, Xiaozhen Huang, De-gang Zhao, Yichen Zhao, Lei Peng
Summary: This study explored the molecular mechanism of Eucommia ulmoides counteracting Fusarium oxysporum infection through transcriptomic and proteomic analyses. The response of Eucommia ulmoides to Fusarium oxysporum was found to be potentially related to the unfolded protein response of the endoplasmic reticulum pathway.
FRONTIERS IN CHEMISTRY
(2022)
Article
Chemistry, Medicinal
Pinger Wang, Jianbo Xu, Qi Sun, Qinwen Ge, Min Qiu, Kaiao Zou, Jun Ying, Wenhua Yuan, Jiali Chen, Qinghe Zeng, Qi Cui, Hongting Jin, Chunchun Zhang, Fanzhu Li
Summary: This study analyzed the active chemical constituents and therapeutic effects of Eucommia ulmoides Oliv. and Glycyrrhiza uralensis Fisch. couplet medicines on knee osteoarthritis (KOA) using UPLC-Q-TOF/MS technique and in vivo experiments. Network pharmacology and molecular docking were employed to predict potential targets for the anti-KOA activities, and PPARG was identified as a therapeutic center. The results suggested that Eucommia ulmoides Oliv. and Glycyrrhiza uralensis Fisch. couplet medicines played a chondroprotective role in treating KOA by inhibiting extracellular matrix degradation.
DRUG DESIGN DEVELOPMENT AND THERAPY
(2023)
Article
Microbiology
Chunbo Dong, Qiuyu Shao, Yulian Ren, Wei Ge, Ting Yao, Haiyan Hu, Jianzhong Huang, Zongqi Liang, Yanfeng Han
Summary: Medicinal plants rely on diverse microbes for their growth, development, and stress resistance. This study explored the effects of environmental factors on the assembly of bacterial communities in the rhizosphere soil and bark of Eucommia ulmoides, and deciphered the phenotypic and metabolic characteristics of the core microbiota and their relationship with pharmacologically active compounds.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Integrative & Complementary Medicine
Yan Zhang, Jian-Ying Wang, Hao Wang, Xiao-Yun Chen, Lei Zhang, Ying Yuan
Summary: The study demonstrated that Eucommia ulmoides Oliv. (EF) has potential therapeutic effects on rheumatoid arthritis by inhibiting synoviocyte proliferation and promoting apoptosis through the NF-kappa B pathway, as well as delaying bone destruction.
Article
Environmental Sciences
Chunbo Dong, Qiuyu Shao, Qingqing Zhang, Ting Yao, Jianzhong Huang, Zongqi Liang, Yanfeng Han
Summary: This study explored the strengths and limitations of four different definition methods for the core microbiome, revealing similarities in function but differences in preferences for microbial communities. The findings suggest that selecting an appropriate method for defining the core microbiome is crucial.
SCIENCE OF THE TOTAL ENVIRONMENT
(2021)
Review
Biochemistry & Molecular Biology
Yan Liu, Tianbao Lin, Maria Valderrama Valencia, Cankui Zhang, Zhiqiang Lv
Summary: Vascular bundles play crucial roles in transporting nutrients and signals in plants. Proteomic analyses are instrumental in identifying the roles of proteins within vascular tissues, contributing to our understanding of plant development and defense mechanisms.
Article
Biotechnology & Applied Microbiology
Ping Mo, Kaiqin Li, Jinhua Zhou, Fumin Zhou, Jiang He, Wansheng Zou, Jian Gao
Summary: Strain Mg02(T) was isolated from the roots of Eucommia ulmoides Oliv. collected from Changde City, Hunan Province, China. The strain showed distinct chemotaxonomic characteristics of the genus Nocardiopsis and phylogenetic analysis suggested that it could be a novel Nocardiopsis species. Therefore, a new species, Nocardiopsis changdeensis sp. nov., is proposed with Mg02(T) as the type strain.
JOURNAL OF ANTIBIOTICS
(2023)
Article
Plant Sciences
Jun Zeng, Qi Ding, Hiroo Fukuda, Xin-Qiang He
JOURNAL OF EXPERIMENTAL BOTANY
(2016)
Article
Plant Sciences
Qi Ding, Jun Zeng, Xin-Qiang He
JOURNAL OF PLANT PHYSIOLOGY
(2016)
Article
Biochemistry & Molecular Biology
Jundi Liu, Jie Hou, Huimin Chen, Keliang Pei, Yi Li, Xin-Qiang He
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2017)
Article
Plant Sciences
Feng Jin, Jing Li, Qi Ding, Qing-Song Wang, Xin-Qiang He
JOURNAL OF PLANT PHYSIOLOGY
(2017)
Article
Plant Sciences
Wan-Feng Li, Qi Ding, Ke-Ming Cui, Xin-Qiang He
ACTA PHYSIOLOGIAE PLANTARUM
(2013)
Article
Plant Sciences
Qi Ding, Jun Zeng, Xin-Qiang He
Article
Biochemistry & Molecular Biology
Hui-Min Chen, Yu Pang, Jun Zeng, Qi Ding, Shen-Yi Yin, Chao Liu, Meng-Zhu Lu, Ke-Ming Cui, Xin-Qiang He
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2012)
Review
Biochemistry & Molecular Biology
William J. Lucas, Andrew Groover, Raffael Lichtenberger, Kaori Furuta, Shri-Ram Yadav, Yka Helariutta, Xin-Qiang He, Hiroo Fukuda, Julie Kang, Siobhan M. Brady, John W. Patrick, John Sperry, Akiko Yoshida, Ana-Flor Lopez-Millan, Michael A. Grusak, Pradeep Kachroo
JOURNAL OF INTEGRATIVE PLANT BIOLOGY
(2013)
Article
Plant Sciences
Jing Zhang, Ge Gao, Jia-Jia Chen, Gail Taylor, Ke-Ming Cui, Xin-Qiang He
Article
Plant Sciences
Zongbo Qiu, Lichuan Wan, Tong Chen, Yinglang Wan, Xinqiang He, Shanfa Lu, Yanwei Wang, Jinxing Lin
Review
Plant Sciences
Jia-Jia Chen, Jing Zhang, Xin-Qiang He
PHYSIOLOGIA PLANTARUM
(2014)
Article
Biochemical Research Methods
Lu Zhao, Qi Ding, Jun Zeng, Fu-Rong Wang, Jun Zhang, Shou-Jin Fan, Xin-Qiang He
PHYTOCHEMICAL ANALYSIS
(2012)
Article
Plant Sciences
Jia-Jia Han, Wei Lin, Yoshihisa Oda, Ke-Ming Cui, Hiroo Fukuda, Xin-Qiang He
Article
Forestry
Hui-Min Chen, Jia-Jia Han, Ke-Ming Cui, Xin-Qiang He
TREES-STRUCTURE AND FUNCTION
(2010)
Article
Biochemistry & Molecular Biology
Fuqiang Cui, Mikael Brosche, Alexey Shapiguzov, Xin-Qiang He, Julia P. Vainonen, Johanna Leppala, Andrea Trotta, Saijaliisa Kangasjarvi, Jarkko Salojarvi, Jaakko Kangasjarvi, Kirk Overmyer
FREE RADICAL BIOLOGY AND MEDICINE
(2019)