Non-alcoholic fatty liver disease as a consequence of autonomic imbalance and circadian desynchronization

Circadian Rhythm of Circulating Levels of the Endocannabinoid 2-Arachidonoylglycerol

(2015) E. C. Hanlon et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Association between non-alcoholic fatty liver disease and autonomic dysfunction in a Chinese population

(2015) W. Sun et al.   QJM-AN INTERNATIONAL JOURNAL OF MEDICINE

Oxidation–Reduction Cycles of Peroxiredoxin Proteins and Nontranscriptional Aspects of Timekeeping

(2014) Nathaniel P. Hoyle et al.   BIOCHEMISTRY

Physiological regulation of lipoprotein lipase

(2014) Sander Kersten   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Peroxiredoxin 6, a Novel Player in the Pathogenesis of Diabetes

(2014) F. Pacifici et al.   DIABETES

Vagal Hyperactivity Due to Ventromedial Hypothalamic Lesions Increases Adiponectin Production and Release

(2014) Yoko Suzuki et al.   DIABETES

Circadian Misalignment Augments Markers of Insulin Resistance and Inflammation, Independently of Sleep Loss

(2014) Rachel Leproult et al.   DIABETES

External validation of the fatty liver index and lipid accumulation product indices, using 1H-magnetic resonance spectroscopy, to identify hepatic steatosis in healthy controls and obese, insulin-resistant individuals

(2014) Daniel J Cuthbertson et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The circadian clock regulates rhythmic activation of the NRF2/glutathione-mediated antioxidant defense pathway to modulate pulmonary fibrosis

(2014) V. Pekovic-Vaughan et al.   GENES & DEVELOPMENT

Hepatic Differentiated Embryo-Chondrocyte-expressed Gene 1 (Dec1) Inhibits Sterol Regulatory Element-binding Protein-1c (Srebp-1c) Expression and Alleviates Fatty Liver Phenotype

(2014) Lian Shen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reciprocal interaction between the suprachiasmatic nucleus and the immune system tunes down the inflammatory response to lipopolysaccharide

(2014) Natalí N. Guerrero-Vargas et al.   JOURNAL OF NEUROIMMUNOLOGY

Non-alcoholic fatty liver disease: the role of nuclear receptors and circadian rhythmicity

(2014) Gianluigi Mazzoccoli et al.   LIVER INTERNATIONAL

Non-Alcoholic Fatty Pancreas Disease Pathogenesis: A Role for Developmental Programming and Altered Circadian Rhythms

(2014) Rebeca Carter et al.   PLoS One

Consuming More of Daily Caloric Intake at Dinner Predisposes to Obesity. A 6-Year Population-Based Prospective Cohort Study

(2014) Simona Bo et al.   PLoS One

The autonomic nervous system regulates postprandial hepatic lipid metabolism

(2013) Eveline Bruinstroop et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals

(2013) Howard C. Masuoka et al.   Annals of the New York Academy of Sciences

Glucagon-Induced Acetylation of Foxa2 Regulates Hepatic Lipid Metabolism

(2013) Ferdinand von Meyenn et al.   Cell Metabolism

Resistance exercise improves autonomic regulation at rest and haemodynamic response to exercise in non-alcoholic fatty liver disease

(2013) Djordje G. Jakovljevic et al.   CLINICAL SCIENCE

Circadian Regulation of Lipid Mobilization in White Adipose Tissues

(2013) A. Shostak et al.   DIABETES

Mitochondrial adaptations and dysfunctions in nonalcoholic fatty liver disease

(2013) Karima Begriche et al.   HEPATOLOGY

Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease

(2013) Yuki Kawano et al.   JOURNAL OF GASTROENTEROLOGY

Cannabinoid signaling and liver therapeutics

(2013) Ariane Mallat et al.   JOURNAL OF HEPATOLOGY

Bmal1 and  -Cell Clock Are Required for Adaptation to Circadian Disruption, and Their Loss of Function Leads to Oxidative Stress-Induced  -Cell Failure in Mice

(2013) J. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

From NAFLD to NASH to cirrhosis—new insights into disease mechanisms

(2013) Alexander Wree et al.   Nature Reviews Gastroenterology & Hepatology

Shift Work or Food Intake during the Rest Phase Promotes Metabolic Disruption and Desynchrony of Liver Genes in Male Rats

(2013) Roberto C. Salgado-Delgado et al.   PLoS One

Circadian Clock NAD+ Cycle Drives Mitochondrial Oxidative Metabolism in Mice

(2013) C. B. Peek et al.   SCIENCE

Lipoprotein Metabolism, Dyslipidemia, and Nonalcoholic Fatty Liver Disease

(2013) Edward Fisher et al.   SEMINARS IN LIVER DISEASE

What is the role of adiponectin in obesity related non-alcoholic fatty liver disease?

(2013) Carmine Finelli   WORLD JOURNAL OF GASTROENTEROLOGY

Pathogenesis of hepatic steatosis: The link between hypercortisolism and non-alcoholic fatty liver disease

(2013) Giovanni Tarantino   WORLD JOURNAL OF GASTROENTEROLOGY

The Diagnosis and Management of Non-alcoholic Fatty Liver Disease: Practice Guideline by the American Association for the Study of Liver Diseases, American College of Gastroenterology and the American Gastroenterological Association

(2012) Naga Chalasani et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Large increases in adipose triacylglycerol flux in Cushingoid CRH-Tg mice are explained by futile cycling

(2012) Charles Harris et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Regional Sympathetic Blockade Attenuates Activation of Intestinal Macrophages and Reduces Gut Barrier Failure

(2012) Jörn Schäper et al.   ANESTHESIOLOGY

Circadian Rhythm Connections to Oxidative Stress: Implications for Human Health

(2012) Melissa Wilking et al.   ANTIOXIDANTS & REDOX SIGNALING

Apolipoprotein B Secretory Regulation by Degradation

(2012) Sven-Olof Olofsson et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

The Scap/SREBP Pathway Is Essential for Developing Diabetic Fatty Liver and Carbohydrate-Induced Hypertriglyceridemia in Animals

(2012) Young-Ah Moon et al.   Cell Metabolism

Hypothalamic Neuropeptide Y (NPY) Controls Hepatic VLDL-Triglyceride Secretion in Rats via the Sympathetic Nervous System

(2012) Eveline Bruinstroop et al.   DIABETES

Skeletal Muscle Insulin Resistance Promotes Increased Hepatic De Novo Lipogenesis, Hyperlipidemia, and Hepatic Steatosis in the Elderly

(2012) C. Flannery et al.   DIABETES

Role of Obesity and Lipotoxicity in the Development of Nonalcoholic Steatohepatitis: Pathophysiology and Clinical Implications

(2012) Kenneth Cusi   GASTROENTEROLOGY

Whole-body substrate metabolism is associated with disease severity in patients with non-alcoholic fatty liver disease

(2012) Ilaria Croci et al.   GUT

NASH is an Infl ammatory Disorder: Pathogenic, Prognostic and Therapeutic Implications

(2012) Geoffrey C. Farrell et al.   Gut and Liver

Quantitative analysis of light-phase restricted feeding reveals metabolic dyssynchrony in mice

(2012) M S Bray et al.   INTERNATIONAL JOURNAL OF OBESITY

Children with NAFLD Are More Sensitive to the Adverse Metabolic Effects of Fructose Beverages than Children without NAFLD

(2012) Ran Jin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Gut–liver axis: The impact of gut microbiota on non alcoholic fatty liver disease

(2012) D. Compare et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Diurnal Variation of Hepatic Antioxidant Gene Expression in Mice

(2012) Yi-Qiao Xu et al.   PLoS One

Regulation of triglyceride metabolism by glucocorticoid receptor

(2012) Jen-Chywan Wang et al.   Cell and Bioscience

Excessive Hepatic Mitochondrial TCA Cycle and Gluconeogenesis in Humans with Nonalcoholic Fatty Liver Disease

(2011) Nishanth E. Sunny et al.   Cell Metabolism

Circadian disruption and SCN control of energy metabolism

(2011) Andries Kalsbeek et al.   FEBS LETTERS

Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides

(2011) Sue Goo Rhee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perilipin 5, a lipid droplet-associated protein, provides physical and metabolic linkage to mitochondria

(2011) Hong Wang et al.   JOURNAL OF LIPID RESEARCH

Mitochondrial production of reactive oxygen species contributes to the β-adrenergic stimulation of mouse cardiomycytes

(2011) Daniel C. Andersson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Oxidative stress in health and disease: The therapeutic potential of Nrf2 activation

(2011) Brooks M. Hybertson et al.   MOLECULAR ASPECTS OF MEDICINE

The cAMP/PKA Pathway Rapidly Activates SIRT1 to Promote Fatty Acid Oxidation Independently of Changes in NAD+

(2011) Zachary Gerhart-Hines et al.   MOLECULAR CELL

Reversal of muscle insulin resistance with exercise reduces postprandial hepatic de novo lipogenesis in insulin resistant individuals

(2011) R. Rabol et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sensing pulmonary oxidative stress by lung vagal afferents

(2011) Thomas E. Taylor-Clark et al.   RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY

Sleep and autonomic nervous system changes – enhanced cardiac sympathetic modulations during sleep in permanent night shift nurses

(2011) Min-Huey Chung et al.   SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH

Heart rate variability and endothelial function after sleep deprivation and recovery sleep among male shift and non-shift workers

(2011) Sophie MT Wehrens et al.   SCANDINAVIAN JOURNAL OF WORK ENVIRONMENT & HEALTH

A Circadian Rhythm Orchestrated by Histone Deacetylase 3 Controls Hepatic Lipid Metabolism

(2011) D. Feng et al.   SCIENCE

Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance

(2011) Sung Hee Choi et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Vagal nerve stimulation protects against burn-induced intestinal injury through activation of enteric glia cells

(2010) Todd W. Costantini et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

The Role of Muscle Insulin Resistance in the Pathogenesis of Atherogenic Dyslipidemia and Nonalcoholic Fatty Liver Disease Associated with the Metabolic Syndrome

(2010) François R. Jornayvaz et al.   Annual Review of Nutrition

Endocannabinoid signalling: has it got rhythm?

(2010) Linda K Vaughn et al.   BRITISH JOURNAL OF PHARMACOLOGY

Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues

(2010) Marcella Fulco et al.   CELL CYCLE

Circadian Clock-Coordinated 12 Hr Period Rhythmic Activation of the IRE1α Pathway Controls Lipid Metabolism in Mouse Liver

(2010) Gaspard Cretenet et al.   Cell Metabolism

Downregulation of Adipose Tissue Fatty Acid Trafficking in Obesity: A Driver for Ectopic Fat Deposition?

(2010) S. E. McQuaid et al.   DIABETES

Day/night variations of high-molecular-weight adiponectin and lipocalin-2 in healthy men studied under fed and fasted conditions

(2010) F. A. J. L. Scheer et al.   DIABETOLOGIA

From the metabolic syndrome to NAFLD or vice versa?

(2010) Ester Vanni et al.   DIGESTIVE AND LIVER DISEASE

Food Intake during the Normal Activity Phase Prevents Obesity and Circadian Desynchrony in a Rat Model of Night Work

(2010) Roberto Salgado-Delgado et al.   ENDOCRINOLOGY

Non-alcoholic fatty liver disease as a risk factor for hepatocellular carcinoma: mechanisms and implications

(2010) F. Stickel et al.   GUT

Disease progression of non-alcoholic fatty liver disease: a prospective study with paired liver biopsies at 3 years

(2010) V. W.-S. Wong et al.   GUT

Evolution of inflammation in nonalcoholic fatty liver disease: The multiple parallel hits hypothesis

(2010) Herbert Tilg et al.   HEPATOLOGY

Autonomic nervous system activity is independently associated with the risk of shift in the non-dipper blood pressure pattern

(2010) Virginie Dauphinot et al.   HYPERTENSION RESEARCH

Time of Day and Nutrients in Feeding Govern Daily Expression Rhythms of the Gene for Sterol Regulatory Element-binding Protein (SREBP)-1 in the Mouse Liver

(2010) Eriko Matsumoto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Novel Evidence for Chronic Exposure to Endotoxin in Human Nonalcoholic Steatohepatitis

(2010) Froukje J. Verdam et al.   JOURNAL OF CLINICAL GASTROENTEROLOGY

Dysregulation of Inflammatory Responses by Chronic Circadian Disruption

(2010) O. Castanon-Cervantes et al.   JOURNAL OF IMMUNOLOGY

Cold-induced alteration of adipokine profile in humans

(2010) K. Alexander Iwen et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Circadian variations in gene expression in rat abdominal adipose tissue and relationship to physiology

(2010) Siddharth Sukumaran et al.   PHYSIOLOGICAL GENOMICS

The Comparison between Circadian Oscillators in Mouse Liver and Pituitary Gland Reveals Different Integration of Feeding and Light Schedules

(2010) Isabelle M. Bur et al.   PLoS One

Fatigue and autonomic dysfunction in non-alcoholic fatty liver disease

(2009) Julia L. Newton et al.   CLINICAL AUTONOMIC RESEARCH

Increased intestinal permeability and tight junction alterations in nonalcoholic fatty liver disease

(2009) Luca Miele et al.   HEPATOLOGY

Adiponectin prevents progression of steatohepatitis in mice by regulating oxidative stress and Kupffer cell phenotype polarization

(2009) Juichi Fukushima et al.   HEPATOLOGY RESEARCH

Hepatic VLDL assembly is disturbed in a rat model of nonalcoholic fatty liver disease: is there a role for dietary coenzyme Q?

(2009) Ainara Cano et al.   JOURNAL OF APPLIED PHYSIOLOGY

Fasted to Fed Trafficking of Fatty Acids in Human Adipose Tissue Reveals a Novel Regulatory Step for Enhanced Fat Storage

(2009) Toralph Ruge et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Clock is important for food and circadian regulation of macronutrient absorption in mice

(2009) Xiaoyue Pan et al.   JOURNAL OF LIPID RESEARCH

Circadian Timing of Food Intake Contributes to Weight Gain

(2009) Deanna M. Arble et al.   Obesity

Time of feeding and the intrinsic circadian clock drive rhythms in hepatic gene expression

(2009) Christopher Vollmers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A moderate increase in carnitine palmitoyltransferase 1a activity is sufficient to substantially reduce hepatic triglyceride levels

(2008) Maja Stefanovic-Racic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Malonyl-CoA, a Key Signaling Molecule in Mammalian Cells

(2008) David Saggerson   Annual Review of Nutrition

Nonalcoholic fatty liver disease and nonalcoholic steatohepatitis: Selected practical issues in their evaluation and management

(2008) Raj Vuppalanchi et al.   HEPATOLOGY

Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease

(2008) Hironori Mitsuyoshi et al.   HEPATOLOGY RESEARCH

Contribution of de novo fatty acid synthesis to hepatic steatosis and insulin resistance: lessons from genetically engineered mice

(2008) Catherine Postic et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular processes that handle — and mishandle — dietary lipids

(2008) Kevin Jon Williams   JOURNAL OF CLINICAL INVESTIGATION

Glucocorticoids and cyclic AMP selectively increase hepatic lipin-1 expression, and insulin acts antagonistically

(2008) Boripont Manmontri et al.   JOURNAL OF LIPID RESEARCH

Lipolysis and the integrated physiology of lipid energy metabolism

(2008) Shupei Wang et al.   MOLECULAR GENETICS AND METABOLISM

Molecular Mechanisms and Therapeutic Targets in Steatosis and Steatohepatitis

(2008) N. Anderson et al.   PHARMACOLOGICAL REVIEWS