标题
Recent progress in copolymer-mediated siRNA delivery
作者
关键词
-
出版物
JOURNAL OF DRUG TARGETING
Volume 20, Issue 7, Pages 551-560
出版商
Informa UK Limited
发表日期
2012-07-05
DOI
10.3109/1061186x.2012.699057
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Multifunctional Triblock Nanocarrier (PAMAM-PEG-PLL) for the Efficient Intracellular siRNA Delivery and Gene Silencing
- (2011) Mahesh L. Patil et al. ACS Nano
- Traceable Multifunctional Micellar Nanocarriers for Cancer-Targeted Co-delivery of MDR-1 siRNA and Doxorubicin
- (2011) Xiao-Bing Xiong et al. ACS Nano
- Using drug-excipient interactions for siRNA delivery
- (2011) Katharina Bruno ADVANCED DRUG DELIVERY REVIEWS
- Differentially Charged Hollow Core/Shell Lipid-Polymer-Lipid Hybrid Nanoparticles for Small Interfering RNA Delivery
- (2011) Jinjun Shi et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- Effect of Polymer Structure on Micelles Formed between siRNA and Cationic Block Copolymer Comprising Thiols and Amidines
- (2011) R. James Christie et al. BIOMACROMOLECULES
- Synthesis of Folate-Functionalized RAFT Polymers for Targeted siRNA Delivery
- (2011) Danielle S. W. Benoit et al. BIOMACROMOLECULES
- Synthesis of Biocompatible PEG-Based Star Polymers with Cationic and Degradable Core for siRNA Delivery
- (2011) Hong Y. Cho et al. BIOMACROMOLECULES
- Diblock Glycopolymers Promote Colloidal Stability of Polyplexes and Effective pDNA and siRNA Delivery under Physiological Salt and Serum Conditions
- (2011) Adam E. Smith et al. BIOMACROMOLECULES
- Local delivery of siRNA using a biodegradable polymer application to enhance BMP-induced bone formation
- (2011) Tomoya Manaka et al. BIOMATERIALS
- Dual mode polyspermine with tunable degradability for plasmid DNA and siRNA delivery
- (2011) Min Suk Shim et al. BIOMATERIALS
- A single-monomer derived linear-like PEI-co-PEG for siRNA delivery and silencing
- (2011) Lin-Ren Tsai et al. BIOMATERIALS
- Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery
- (2011) Daoshu Lin et al. BIOMATERIALS
- Co-delivery of small interfering RNA and plasmid DNA using a polymeric vector incorporating endosomolytic oligomeric sulfonamide
- (2011) Han Chang Kang et al. BIOMATERIALS
- Enhanced siRNA delivery into cells by exploiting the synergy between targeting ligands and cell-penetrating peptides
- (2011) Christopher J. Cheng et al. BIOMATERIALS
- Chitosan-graft-(PEI-β-cyclodextrin) copolymers and their supramolecular PEGylation for DNA and siRNA delivery
- (2011) Yuan Ping et al. BIOMATERIALS
- Enhanced endosomal escape of siRNA-incorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity
- (2011) Frederico Pittella et al. BIOMATERIALS
- A biodegradable amphiphilic and cationic triblock copolymer for the delivery of siRNA targeting the acid ceramidase gene for cancer therapy
- (2011) Cheng-Qiong Mao et al. BIOMATERIALS
- Polymer therapeutics as nanomedicines: new perspectives
- (2011) Ruth Duncan CURRENT OPINION IN BIOTECHNOLOGY
- Inhibitory effect of siRNA complexes with polyamidoamine dendrimer/α-cyclodextrin conjugate (generation 3, G3) on endogenous gene expression
- (2011) Hidetoshi Arima et al. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES
- Co-delivery of anti-vascular endothelial growth factor siRNA and doxorubicin by multifunctional polymeric micelle for tumor growth suppression
- (2011) Hong-Yi Huang et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Biophysical characterization of hyper-branched polyethylenimine-graft- polycaprolactone-block-mono-methoxyl-poly(ethylene glycol) copolymers (hy-PEI-PCL-mPEG) for siRNA delivery
- (2011) Yu Liu et al. JOURNAL OF CONTROLLED RELEASE
- Anionic polymers for decreased toxicity and enhanced in vivo delivery of siRNA complexed with cationic liposomes
- (2011) Anne Schlegel et al. JOURNAL OF CONTROLLED RELEASE
- Synthesis of Poly(propylene glycol)-block-Polyethylenimine Triblock Copolymers for the Delivery of Nucleic Acids
- (2011) Blandine Brissault et al. MACROMOLECULAR BIOSCIENCE
- Efficient Intracellular siRNA Delivery by Ethyleneimine-Modified Amphiphilic Macromolecules
- (2011) Sarah M. Sparks et al. MACROMOLECULAR BIOSCIENCE
- Impact of Lipid Substitution on Assembly and Delivery of siRNA by Cationic Polymers
- (2011) Hamidreza Montazeri Aliabadi et al. MACROMOLECULAR BIOSCIENCE
- Synergistic Induction of Apoptosis in Brain Cancer Cells by Targeted Codelivery of siRNA and Anticancer Drugs
- (2011) Cheoljin Kim et al. MOLECULAR PHARMACEUTICS
- Induction of Apoptosis by Survivin Silencing through siRNA Delivery in a Human Breast Cancer Cell Line
- (2011) Hamidreza Montazeri Aliabadi et al. MOLECULAR PHARMACEUTICS
- Combinatorial synthesis of chemically diverse core-shell nanoparticles for intracellular delivery
- (2011) Daniel J. Siegwart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Poly-l-lysine-coated albumin nanoparticles: Stability, mechanism for increasing in vitro enzymatic resilience, and siRNA release characteristics
- (2010) Harsh Deep Singh et al. Acta Biomaterialia
- Biochemical Principles of Small RNA Pathways
- (2010) Qinghua Liu et al. Annual Review of Biochemistry
- Rational Design of Targeted Cancer Therapeutics through the Multiconjugation of Folate and Cleavable siRNA to RAFT-Synthesized (HPMA-s-APMA) Copolymers†
- (2010) Adam W. York et al. BIOMACROMOLECULES
- pH-Responsive Polymeric Micelle Carriers for siRNA Drugs
- (2010) A. J. Convertine et al. BIOMACROMOLECULES
- Primary cardiomyocyte-targeted bioreducible polymer for efficient gene delivery to the myocardium
- (2010) Hye Y. Nam et al. BIOMATERIALS
- Target specific tumor treatment by VEGF siRNA complexed with reducible polyethyleneimine–hyaluronic acid conjugate
- (2010) Kitae Park et al. BIOMATERIALS
- Virus-mimetic polymeric micelles for targeted siRNA delivery
- (2010) Xiao-Bing Xiong et al. BIOMATERIALS
- Polyion complex stability and gene silencing efficiency with a siRNA-grafted polymer delivery system
- (2010) Hiroyasu Takemoto et al. BIOMATERIALS
- Degradable, pH-sensitive, membrane-destabilizing, comb-like polymers for intracellular delivery of nucleic acids
- (2010) Yen-Ling Lin et al. BIOMATERIALS
- Polymer-related off-target effects in non-viral siRNA delivery
- (2010) Olivia M. Merkel et al. BIOMATERIALS
- The synergistic effect of hierarchical assemblies of siRNA and chemotherapeutic drugs co-delivered into hepatic cancer cells
- (2010) Nuo Cao et al. BIOMATERIALS
- PAMAM Dendrimers for siRNA Delivery: Computational and Experimental Insights
- (2010) Giovanni Maria Pavan et al. CHEMISTRY-A EUROPEAN JOURNAL
- Efficient delivery of intact phosphodiester oligonucleotides by poly-β-amino esters
- (2010) K. Remaut et al. JOURNAL OF CONTROLLED RELEASE
- RNA interference in vitro and in vivo using an arginine peptide/siRNA complex system
- (2010) Sung Wook Kim et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Myung Sook Huh et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Atsushi Tamura et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Christina Kriegel et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Brenda F. Canine et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Amir K. Varkouhi et al. JOURNAL OF CONTROLLED RELEASE
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- (2010) Ulrik L. Rahbek et al. JOURNAL OF DRUG TARGETING
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- (2010) Chunsoo Kim et al. LANGMUIR
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- (2010) Yutaka Ikeda et al. MACROMOLECULAR BIOSCIENCE
- Reductive Degradation Behavior of Bioreducible Poly(disulfide amine) for Enhancing SiRNA Efficiency
- (2010) Sun Hwa Kim et al. MACROMOLECULAR BIOSCIENCE
- pH-Responsive Polymeric siRNA Carriers Sensitize Multidrug Resistant Ovarian Cancer Cells to Doxorubicin via Knockdown of Polo-like Kinase 1
- (2010) Danielle S. W. Benoit et al. MOLECULAR PHARMACEUTICS
- Leukemia-specific siRNA delivery by immunonanoplexes consisting of anti-JL1 minibody conjugated to oligo-9 Arg-peptides
- (2010) Yeon Kyung Lee et al. MOLECULES AND CELLS
- Chitosan/siRNA Nanoparticles Biofunctionalize Nerve Implants and Enable Neurite Outgrowth
- (2010) Ursula Mittnacht et al. NANO LETTERS
- Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines
- (2010) D. Scott Wilson et al. NATURE MATERIALS
- Amine-Modified Poly(Vinyl Alcohol)s as Non-viral Vectors for siRNA Delivery: Effects of the Degree of Amine Substitution on Physicochemical Properties and Knockdown Efficiency
- (2010) Juliane Nguyen et al. PHARMACEUTICAL RESEARCH
- Functional modification of amide-crosslinked oligoethylenimine for improved siRNA delivery
- (2010) Alexander Philipp et al. REACTIVE & FUNCTIONAL POLYMERS
- siRNA delivery systems for cancer treatment
- (2009) Yu-Kyoung Oh et al. ADVANCED DRUG DELIVERY REVIEWS
- Enhanced Cytoplasmic Delivery of siRNA Using a Stabilized Polyion Complex Based on PEGylated Nanogels with a Cross-Linked Polyamine Structure
- (2009) Atsushi Tamura et al. BIOMACROMOLECULES
- Development of a Functionalized Polymer for Stent Coating in the Arterial Delivery of Small Interfering RNA
- (2009) Aurélie San Juan et al. BIOMACROMOLECULES
- In-situ crosslinking hydrogels for combinatorial delivery of chemokines and siRNA–DNA carrying microparticles to dendritic cells
- (2009) Ankur Singh et al. BIOMATERIALS
- Targeted intracellular codelivery of chemotherapeutics and nucleic acid with a well-defined dendrimer-based nanoglobular carrier
- (2009) Todd L. Kaneshiro et al. BIOMATERIALS
- The induction of tumor apoptosis in B16 melanoma following STAT3 siRNA delivery with a lipid-substituted polyethylenimine
- (2009) Aws Alshamsan et al. BIOMATERIALS
- Silencing of proinflammatory genes targeted to peritoneal-residing macrophages using siRNA encapsulated in biodegradable microspheres
- (2009) Tali Brunner et al. BIOMATERIALS
- Chitosan-graft-polyethylenimine for Akt1 siRNA delivery to lung cancer cells
- (2009) Dhananjay Jere et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Preparation and characterization of poly(dl-lactide-co-glycolide) nanoparticles for siRNA delivery
- (2009) Dongmei Cun et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Efficient intracellular siRNA delivery strategy through rapid and simple two steps mixing involving noncovalent post-PEGylation
- (2009) Won-Ho Kong et al. JOURNAL OF CONTROLLED RELEASE
- Novel biodegradable lipid nano complex for siRNA delivery significantly improving the chemosensitivity of human colon cancer stem cells to paclitaxel
- (2009) Changxing Liu et al. JOURNAL OF CONTROLLED RELEASE
- Stability of siRNA polyplexes from poly(ethylenimine) and poly(ethylenimine)-g-poly(ethylene glycol) under in vivo conditions: Effects on pharmacokinetics and biodistribution measured by Fluorescence Fluctuation Spectroscopy and Single Photon Emission Computed Tomography (SPECT) imaging
- (2009) Olivia M. Merkel et al. JOURNAL OF CONTROLLED RELEASE
- Anionic amino acid-derived cationic lipid for siRNA delivery
- (2009) Min Sung Suh et al. JOURNAL OF CONTROLLED RELEASE
- Monitoring the disassembly of siRNA polyplexes in serum is crucial for predicting their biological efficacy
- (2009) Kevin Buyens et al. JOURNAL OF CONTROLLED RELEASE
- Stability and cellular uptake of polymerized siRNA (poly-siRNA)/polyethylenimine (PEI) complexes for efficient gene silencing
- (2009) Seung-Young Lee et al. JOURNAL OF CONTROLLED RELEASE
- Spray drying of siRNA-containing PLGA nanoparticles intended for inhalation
- (2009) Ditte Marie Krohn Jensen et al. JOURNAL OF CONTROLLED RELEASE
- Reversibly crosslinked temperature-responsive nano-sized polymersomes: synthesis and triggered drug release
- (2009) Haifei Xu et al. JOURNAL OF MATERIALS CHEMISTRY
- Access to Poly-β-Peptides with Functionalized Side Chains and End Groups via Controlled Ring-Opening Polymerization of β-Lactams
- (2009) Jihua Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis and Biological Evaluation of a Bioresponsive and Endosomolytic siRNA−Polymer Conjugate
- (2009) Martin Meyer et al. MOLECULAR PHARMACEUTICS
- Old polymer learns new tracts
- (2009) Michael J. Campolongo et al. NATURE MATERIALS
- Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA
- (2009) Kim A. Woodrow et al. NATURE MATERIALS
- Recognizing and avoiding siRNA off-target effects for target identification and therapeutic application
- (2009) Aimee L. Jackson et al. NATURE REVIEWS DRUG DISCOVERY
- Nanosized polyamidoamine (PAMAM) dendrimer-induced apoptosis mediated by mitochondrial dysfunction
- (2009) Jong-Ho Lee et al. TOXICOLOGY LETTERS
- siRNA Conjugate Delivery Systems
- (2008) Ji Hoon Jeong et al. BIOCONJUGATE CHEMISTRY
- Physicochemical Characteristics and Preliminary in Vivo Biological Evaluation of Nanocapsules Loaded with siRNA Targeting Estrogen Receptor Alpha
- (2008) Céline Bouclier et al. BIOMACROMOLECULES
- Environment-Responsive Block Copolymer Micelles with a Disulfide Cross-Linked Core for Enhanced siRNA Delivery
- (2008) Satoru Matsumoto et al. BIOMACROMOLECULES
- Cardiomyocyte-targeted siRNA delivery by prostaglandin E2-Fas siRNA polyplexes formulated with reducible poly(amido amine) for preventing cardiomyocyte apoptosis
- (2008) Sun Hwa Kim et al. BIOMATERIALS
- Poly(β-amino ester) as a carrier for si/shRNA delivery in lung cancer cells
- (2008) Dhananjay Jere et al. BIOMATERIALS
- Progress in developing cationic vectors for non-viral systemic gene therapy against cancer
- (2008) Marie Morille et al. BIOMATERIALS
- Self-assembled biodegradable micellar nanoparticles of amphiphilic and cationic block copolymer for siRNA delivery
- (2008) Tian-Meng Sun et al. BIOMATERIALS
- Akt1 silencing efficiencies in lung cancer cells by sh/si/ssiRNA transfection using a reductable polyspermine carrier
- (2008) Dhananjay Jere et al. BIOMATERIALS
- Biodegradable amphiphilic poly(ethylene oxide)-block-polyesters with grafted polyamines as supramolecular nanocarriers for efficient siRNA delivery
- (2008) Xiao-Bing Xiong et al. BIOMATERIALS
- Nonviral Vectors for Gene Delivery
- (2008) Meredith A. Mintzer et al. CHEMICAL REVIEWS
- Cellular Delivery In Vivo of siRNA-Based Therapeutics
- (2008) A. Aigner CURRENT PHARMACEUTICAL DESIGN
- State of the art and perspectives for the delivery of antisense oligonucleotides and siRNA by polymeric nanocarriers
- (2008) Elias Fattal et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Preparation of polyethyleneimine incorporated poly(d,l-lactide-co-glycolide) nanoparticles by spontaneous emulsion diffusion method for small interfering RNA delivery
- (2008) Haliza Katas et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Triggered release of siRNA from poly(ethylene glycol)-protected, pH-dependent liposomes
- (2008) D AUGUSTE et al. JOURNAL OF CONTROLLED RELEASE
- Fast degrading polyesters as siRNA nano-carriers for pulmonary gene therapy
- (2008) Juliane Nguyen et al. JOURNAL OF CONTROLLED RELEASE
- A peptide-targeted delivery system with pH-sensitive amphiphilic cell membrane disruption for efficient receptor-mediated siRNA delivery
- (2008) Xu-Li Wang et al. JOURNAL OF CONTROLLED RELEASE
- Development of a novel endosomolytic diblock copolymer for siRNA delivery
- (2008) Anthony J. Convertine et al. JOURNAL OF CONTROLLED RELEASE
- Polymersome delivery of siRNA and antisense oligonucleotides
- (2008) Younghoon Kim et al. JOURNAL OF CONTROLLED RELEASE
- Prolonged gene silencing in hepatoma cells and primary hepatocytes after small interfering RNA delivery with biodegradable poly(β‐amino esters)
- (2008) Roosmarijn E. Vandenbroucke et al. JOURNAL OF GENE MEDICINE
- Breathing Life into Polycations: Functionalization with pH-Responsive Endosomolytic Peptides and Polyethylene Glycol Enables siRNA Delivery
- (2008) Martin Meyer et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Synthesis, Transport and Pharmacokinetics of 5′-Amino Acid Ester Prodrugs of 1-β-d-Arabinofuranosylcytosine
- (2008) Yongbing Sun et al. MOLECULAR PHARMACEUTICS
- Delivery of siRNA from lyophilized polymeric surfaces
- (2007) Morten Ø. Andersen et al. BIOMATERIALS
- A multifunctional and reversibly polymerizable carrier for efficient siRNA delivery
- (2007) Xu-Li Wang et al. BIOMATERIALS
- Thermally sensitive cationic polymer nanocapsules for specific cytosolic delivery and efficient gene silencing of siRNA: Swelling induced physical disruption of endosome by cold shock
- (2007) Soo Hyeon Lee et al. JOURNAL OF CONTROLLED RELEASE
- Breaking the Bonds: Non-viral Vectors Become Chemically Dynamic
- (2007) Jon A Wolff et al. MOLECULAR THERAPY
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