Advances in the Regulation of Osteoclasts and Osteoclast Functions

Inhibitory Immunoglobulin-Like Receptors LILRB and PIR-B Negatively Regulate Osteoclast Development

(2014) Y. Mori et al.   JOURNAL OF IMMUNOLOGY

Advances in osteoclast biology reveal potential new drug targets and new roles for osteoclasts

(2013) Brendan F Boyce   JOURNAL OF BONE AND MINERAL RESEARCH

Coordinated transcriptional regulation of bone homeostasis by Ebf1 and Zfp521 in both mesenchymal and hematopoietic lineages

(2013) Riku Kiviranta et al.   JOURNAL OF EXPERIMENTAL MEDICINE

C/EBP  regulates osteoclast lineage commitment

(2013) W. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Osteoclasts Have Multiple Roles in Bone in Addition to Bone Resorption

(2012) Brendan Boyce et al.   CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION

Do Epigenetic Marks Govern Bone Mass and Homeostasis?

(2012) Jesus Delgado-Calle et al.   CURRENT GENOMICS

The Transcription Factor Jdp2 Controls Bone Homeostasis and Antibacterial Immunity by Regulating Osteoclast and Neutrophil Differentiation

(2012) Kenta Maruyama et al.   IMMUNITY

NF-κB and the link between inflammation and cancer

(2012) Joseph A. DiDonato et al.   IMMUNOLOGICAL REVIEWS

Denosumab: mechanism of action and clinical outcomes

(2012) D. A. Hanley et al.   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Autophagy: A new player in skeletal maintenance?

(2012) Lynne J Hocking et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Role of T cells in ovariectomy induced bone loss-revisited

(2012) Roberto Pacifici   JOURNAL OF BONE AND MINERAL RESEARCH

Osteocyte RANKL: New insights into the control of bone remodeling

(2012) Jinhu Xiong et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Can peripheral bloodγδT cells predict osteonecrosis of the jaw? An immunological perspective on the adverse drug effects of aminobisphosphonate therapy

(2012) Shirin Kalyan et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Vitamin E decreases bone mass by stimulating osteoclast fusion

(2012) Koji Fujita et al.   NATURE MEDICINE

Wnt5a-Ror2 signaling between osteoblast-lineage cells and osteoclast precursors enhances osteoclastogenesis

(2012) Kazuhiro Maeda et al.   NATURE MEDICINE

New developments in osteoimmunology

(2012) Hiroshi Takayanagi   Nature Reviews Rheumatology

Semaphorins in bone development, homeostasis, and disease

(2012) Sujin Kang et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The immunoreceptor tyrosine-based activation motif (ITAM) -related factors are increased in synovial tissue and vasculature of rheumatoid arthritic joints

(2012) Tania N Crotti et al.   ARTHRITIS RESEARCH & THERAPY

Inhibition of Cathepsin K for Treatment of Osteoporosis

(2012) Steven Boonen et al.   Current Osteoporosis Reports

The osteoclast and its unique cytoskeleton

(2011) Steven L. Teitelbaum   Annals of the New York Academy of Sciences

Distinguishing the proapoptotic and antiresorptive functions of risedronate in murine osteoclasts: Role of the Akt pathway and the ERK/Bim axis

(2011) Takumi Matsumoto et al.   ARTHRITIS AND RHEUMATISM

Epigenetic regulation of osteoclast differentiation: Possible involvement of Jmjd3 in the histone demethylation of Nfatc1

(2011) Tetsuro Yasui et al.   JOURNAL OF BONE AND MINERAL RESEARCH

OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice

(2011) Alexander David Barrow et al.   JOURNAL OF CLINICAL INVESTIGATION

Dissecting the Role of the S1P/S1PR Axis in Health and Disease

(2011) J.J. Aarthi et al.   JOURNAL OF DENTAL RESEARCH

The skeleton: a multi-functional complex organ. The role of key signalling pathways in osteoclast differentiation and in bone resorption

(2011) David J Mellis et al.   JOURNAL OF ENDOCRINOLOGY

Regulation of bone by the adaptive immune system in arthritis

(2011) Kazuo Okamoto et al.   ARTHRITIS RESEARCH & THERAPY

Negative regulation of osteoclastogenesis and bone resorption by cytokines and transcriptional repressors

(2011) Baohong Zhao et al.   ARTHRITIS RESEARCH & THERAPY

A review of the efficacy and safety of denosumab in postmenopausal women with osteoporosis

(2011) Paul D. Miller   Therapeutic Advances in Musculoskeletal Disease

TSG-6 inhibits osteoclast activity via an autocrine mechanism and is functionally synergistic with osteoprotegerin

(2010) David J. Mahoney et al.   ARTHRITIS AND RHEUMATISM

RANKL-independent human osteoclast formation with APRIL, BAFF, NGF, IGF I and IGF II

(2010) F. Hemingway et al.   BONE

Biochemical and molecular mechanisms of action of bisphosphonates

(2010) Michael J. Rogers et al.   BONE

Rheumatoid arthritis and periodontal disease

(2010) Jean-Marie Berthelot et al.   JOINT BONE SPINE

The Blimp1–Bcl6 axis is critical to regulate osteoclast differentiation and bone homeostasis

(2010) Yoshiteru Miyauchi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The multiple faces of autoimmune-mediated bone loss

(2010) Georg Schett et al.   Nature Reviews Endocrinology

Osteoclasts and odontoclasts: signaling pathways to development and disease

(2010) Z Wang et al.   ORAL DISEASES

S1P-targeted therapy for elderly rheumatoid arthritis patients with osteoporosis

(2010) Junichi Kikuta et al.   RHEUMATOLOGY INTERNATIONAL

NF-κB p100 limits TNF-induced bone resorption in mice by a TRAF3-dependent mechanism

(2009) Zhenqiang Yao et al.   JOURNAL OF CLINICAL INVESTIGATION

TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation

(2009) Yi Tang et al.   NATURE MEDICINE

Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival

(2008) Susan A Krum et al.   EMBO JOURNAL

Receptor Activator of Nuclear Factor κB Ligand and Osteoprotegerin Regulation of Bone Remodeling in Health and Disease

(2008) Ann E. Kearns et al.   ENDOCRINE REVIEWS

Genetics, pathogenesis and complications of osteopetrosis

(2007) Andrea Del Fattore et al.   BONE