Methylglyoxal Causes Cell Death in Neural Progenitor Cells and Impairs Adult Hippocampal Neurogenesis

Scopoletin Protects against Methylglyoxal-Induced Hyperglycemia and Insulin Resistance Mediated by Suppression of Advanced Glycation Endproducts (AGEs) Generation and Anti-Glycation

(2015) Wen-Chang Chang et al.   MOLECULES

Lead decreases cell survival, proliferation, and neuronal differentiation of primary cultured adult neural precursor cells through activation of the JNK and p38 MAP kinases

(2015) Anna Engstrom et al.   TOXICOLOGY IN VITRO

Activation of transient receptor potential vanilloid 4 induces apoptosis in hippocampus through downregulating PI3K/Akt and upregulating p38 MAPK signaling pathways

(2015) P Jie et al.   Cell Death & Disease

Methylglyoxal, the dark side of glycolysis

(2015) Igor Allaman et al.   Frontiers in Neuroscience

Methylglyoxal increases dopamine level and leads to oxidative stress in SH-SY5Y cells

(2014) Bingjie Xie et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

(2014) James L. Figarola et al.   APOPTOSIS

Methylglyoxal (MG) and Cerebro-Renal Interaction: Does Long-Term Orally Administered MG Cause Cognitive Impairment in Normal Sprague-Dawley Rats?

(2014) Kimio Watanabe et al.   Toxins

Huperzine A promotes hippocampal neurogenesis in vitro and in vivo

(2013) Tuo Ma et al.   BRAIN RESEARCH

Stage-Specific Functions of the Small Rho GTPases Cdc42 and Rac1 for Adult Hippocampal Neurogenesis

(2013) K. C. Vadodaria et al.   JOURNAL OF NEUROSCIENCE

Methylglyoxal-induced cytotoxicity in neonatal rat brain: a role for oxidative stress and MAP kinases

(2013) Luana Heimfarth et al.   METABOLIC BRAIN DISEASE

PKC-dependent ERK phosphorylation is essential for P2X7 receptor-mediated neuronal differentiation of neural progenitor cells

(2013) H-K Tsao et al.   Cell Death & Disease

Possible link between the cognitive dysfunction associated with diabetes mellitus and the neurotoxicity of methylglyoxal

(2012) Xiaobo Huang et al.   BRAIN RESEARCH

Baicalein attenuates impaired hippocampal neurogenesis and the neurocognitive deficits induced by γ-ray radiation

(2012) Shin Bi Oh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Fluoxetine rescues impaired hippocampal neurogenesis in a transgenic A53T synuclein mouse model

(2012) Zacharias Kohl et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Resveratrol Inhibits the Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis

(2012) Hee Ra Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylglyoxal Induces Tau Hyperphosphorylation via Promoting AGEs Formation

(2012) Xiao-Hong Li et al.   NEUROMOLECULAR MEDICINE

Glycation of LDL by Methylglyoxal Increases Arterial Atherogenicity: A Possible Contributor to Increased Risk of Cardiovascular Disease in Diabetes

(2011) N. Rabbani et al.   DIABETES

Concussive Brain Trauma in the Mouse Results in Acute Cognitive Deficits and Sustained Impairment of Axonal Function

(2011) Jennifer A. Creed et al.   JOURNAL OF NEUROTRAUMA

Adult hippocampal neurogenesis and its role in Alzheimer's disease

(2011) Yangling Mu et al.   Molecular Neurodegeneration

Tenuigenin protects cultured hippocampal neurons against methylglyoxal-induced neurotoxicity

(2010) Yu-Jing Chen et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Early exercise promotes positive hippocampal plasticity and improves spatial memory in the adult life of rats

(2010) Sérgio Gomes da Silva et al.   HIPPOCAMPUS

Methylglyoxal Is a Predictor in Type 2 Diabetic Patients of Intima-Media Thickening and Elevation of Blood Pressure

(2010) Susumu Ogawa et al.   HYPERTENSION

Methylglyoxal Content in Drinking Coffee as a Cytotoxic Factor

(2010) J. Wang et al.   JOURNAL OF FOOD SCIENCE

Capsaicin Impairs Proliferation of Neural Progenitor Cells and Hippocampal Neurogenesis in Young Mice

(2010) Kyoung Hye Kong et al.   JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

(2010) Jessica M. Simpson et al.   NEUROBIOLOGY OF DISEASE

Age effects on the regulation of adult hippocampal neurogenesis by physical activity and environmental enrichment in the APP23 mouse model of Alzheimer disease

(2009) Sebastian Mirochnic et al.   HIPPOCAMPUS

Carbonated soft drinks and carbonyl stress burden

(2009) Keisuke Nakayama et al.   JOURNAL OF TOXICOLOGICAL SCIENCES

Advanced glycation endproducts and their receptor RAGE in Alzheimer's disease

(2009) Velandai Srikanth et al.   NEUROBIOLOGY OF AGING

Detection of behavioral alterations and learning deficits in mice lacking synaptophysin

(2009) U. Schmitt et al.   NEUROSCIENCE

Methylglyoxal: Its Presence in Beverages and Potential Scavengers

(2008) Di Tan et al.   Annals of the New York Academy of Sciences

Mechanisms and Functional Implications of Adult Neurogenesis

(2008) Chunmei Zhao et al.   CELL

Exercise enhances the proliferation of neural stem cells and neurite growth and survival of neuronal progenitor cells in dentate gyrus of middle-aged mice

(2008) Chih-Wei Wu et al.   JOURNAL OF APPLIED PHYSIOLOGY

Curcumin Stimulates Proliferation of Embryonic Neural Progenitor Cells and Neurogenesis in the Adult Hippocampus

(2008) So Jung Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

 -Synuclein Alters Notch-1 Expression and Neurogenesis in Mouse Embryonic Stem Cells and in the Hippocampus of Transgenic Mice

(2008) L. Crews et al.   JOURNAL OF NEUROSCIENCE

Cytoprotective effects of phenolic acids on methylglyoxal-induced apoptosis in Neuro-2A cells

(2008) Shang-Ming Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Methylglyoxal causes strong weakening of detoxifying capacity and apoptotic cell death in rat hippocampal neurons

(2007) Silvia Di Loreto et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

BDNF: A key regulator for protein synthesis-dependent LTP and long-term memory?

(2007) Yuan Lu et al.   NEUROBIOLOGY OF LEARNING AND MEMORY