Maternal diet–induced microRNAs and mTOR underlie β cell dysfunction in offspring

MicroRNA-7a regulates pancreatic β cell function

(2014) Mathieu Latreille et al.   JOURNAL OF CLINICAL INVESTIGATION

Developmental and environmental epigenetic programming of the endocrine pancreas: consequences for type 2 diabetes

(2013) Ionel Sandovici et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

MicroRNA-199a-3p Regulates Endometrial Cancer Cell Proliferation by Targeting Mammalian Target of Rapamycin (mTOR)

(2013) Dong Wu et al.   INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER

Direct Measurements of Oscillatory Glycolysis in Pancreatic Islet β-Cells Using Novel Fluorescence Resonance Energy Transfer (FRET) Biosensors for Pyruvate Kinase M2 Activity

(2013) Matthew J. Merrins et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

mTORC2 controls actin polymerization required for consolidation of long-term memory

(2013) Wei Huang et al.   NATURE NEUROSCIENCE

mTORC1 signaling and regulation of pancreatic β-cell mass

(2012) Manuel Blandino-Rosano et al.   CELL CYCLE

MicroRNA-7 Regulates the mTOR Pathway and Proliferation in Adult Pancreatic  -Cells

(2012) Y. Wang et al.   DIABETES

Regulation of Pancreatic microRNA-7 Expression

(2012) Sharon Kredo-Russo et al.   Experimental Diabetes Research

Leucine Is Essential for Attenuating Fetal Growth Restriction Caused by a Protein-Restricted Diet in Rats

(2012) Gabriela Fullin Resende Teodoro et al.   JOURNAL OF NUTRITION

Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes

(2012)   NATURE GENETICS

miR-99 Family of MicroRNAs Suppresses the Expression of Prostate-Specific Antigen and Prostate Cancer Cell Proliferation

(2011) Dandan Sun et al.   CANCER RESEARCH

miR-152 Is a Tumor Suppressor microRNA That Is Silenced by DNA Hypermethylation in Endometrial Cancer

(2011) T. Tsuruta et al.   CANCER RESEARCH

Metabolic Programming, Epigenetics, and Gestational Diabetes Mellitus

(2011) Sara E. Pinney et al.   Current Diabetes Reports

Inflammatory Induction of Human Resistin Causes Insulin Resistance in Endotoxemic Mice

(2011) Hyeong-Kyu Park et al.   DIABETES

L-Leucine Alters Pancreatic  -Cell Differentiation and Function via the mTor Signaling Pathway

(2011) L. Rachdi et al.   DIABETES

Rictor/mTORC2 Is Essential for Maintaining a Balance Between β-Cell Proliferation and Cell Size

(2011) Yanyun Gu et al.   DIABETES

Maternal diet and aging alter the epigenetic control of a promoter-enhancer interaction at the Hnf4a gene in rat pancreatic islets

(2011) I. Sandovici et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neurofibromatosis-1 regulates mTOR-mediated astrocyte growth and glioma formation in a TSC/Rheb-independent manner

(2011) S. Banerjee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Early life nutrition and metabolic programming

(2010) Denise S. Fernandez-Twinn et al.   Annals of the New York Academy of Sciences

MicroRNAs miR-199a-5p and -3p Target the Brm Subunit of SWI/SNF to Generate a Double-Negative Feedback Loop in a Variety of Human Cancers

(2010) K. Sakurai et al.   CANCER RESEARCH

MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells

(2010) Francesca Fornari et al.   CANCER RESEARCH

Pancreatic β Cells Require NeuroD to Achieve and Maintain Functional Maturity

(2010) Chunyan Gu et al.   Cell Metabolism

Decreased IRS Signaling Impairs  -Cell Cycle Progression and Survival in Transgenic Mice Overexpressing S6K in  -Cells

(2010) L. Elghazi et al.   DIABETES

The Effects of Low Protein During Gestation on Mouse Pancreatic Development and Beta Cell Regeneration

(2010) Aaron R Cox et al.   PEDIATRIC RESEARCH

Non-catch-up growth in intrauterine growth-retarded rats showed glucose intolerance and increased expression of PDX-1 mRNA

(2010) Jung Sub Lim et al.   PEDIATRICS INTERNATIONAL

Critical Role for Hypothalamic mTOR Activity in Energy Balance

(2009) Hiroyuki Mori et al.   Cell Metabolism

Upregulation of the Mammalian Target of Rapamycin Complex 1 Pathway by Ras Homolog Enriched in Brain in Pancreatic  -Cells Leads to Increased  -Cell Mass and Prevention of Hyperglycemia

(2009) S. Hamada et al.   DIABETES

Elevated Insulin Sensitivity in Low-protein Offspring Rats Is Prevented by a High-fat Diet and Is Associated With Visceral Fat

(2009) Alison K. Gosby et al.   Obesity

Maternal Low-Protein Diet or Hypercholesterolemia Reduces Circulating Essential Amino Acids and Leads to Intrauterine Growth Restriction

(2008) K. K. S. Bhasin et al.   DIABETES

Assessing the Combined Impact of 18 Common Genetic Variants of Modest Effect Sizes on Type 2 Diabetes Risk

(2008) H. Lango et al.   DIABETES

Development of type 2 diabetes following intrauterine growth retardation in rats is associated with progressive epigenetic silencing of Pdx1

(2008) Jun H. Park et al.   JOURNAL OF CLINICAL INVESTIGATION

Disruption of Tsc2 in pancreatic   cells induces   cell mass expansion and improved glucose tolerance in a TORC1-dependent manner

(2008) L. Rachdi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA