Gene-environment interactions at theFKBP5locus: sensitive periods, mechanisms and pleiotropism

FKBP5 as a possible moderator of the psychosis-inducing effects of childhood trauma

(2013) Dina Collip et al.   BRITISH JOURNAL OF PSYCHIATRY

Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression

(2013) A. Menke et al.   GENES BRAIN AND BEHAVIOR

Accelerated neurodegeneration through chaperone-mediated oligomerization of tau

(2013) Laura J. Blair et al.   JOURNAL OF CLINICAL INVESTIGATION

Increasing the Efficiency of Ligands for FK506-Binding Protein 51 by Conformational Control

(2013) Yansong Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis

(2013)   LANCET

Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin

(2013) A. M. Marz et al.   MOLECULAR AND CELLULAR BIOLOGY

Genome-wide association analysis identifies 13 new risk loci for schizophrenia

(2013) Stephan Ripke et al.   NATURE GENETICS

“Seq-ing” Insights into the Epigenetics of Neuronal Gene Regulation

(2013) Francesca Telese et al.   NEURON

FKBP5 genetic variation

(2013) Katarzyna A. Ellsworth et al.   Pharmacogenetics and Genomics

GR-mediated FKBP5 RNA induction differentially influenced by weight in major depression and healthy controls

(2013) A Menke et al.   PHARMACOPSYCHIATRY

InterAKTions with FKBPs - Mutational and Pharmacological Exploration

(2013) Anne-Katrin Fabian et al.   PLoS One

Contribution of FKBP5 Genetic Variation to Gemcitabine Treatment and Survival in Pancreatic Adenocarcinoma

(2013) Katarzyna A. Ellsworth et al.   PLoS One

FKBP5 and Attention Bias for Threat

(2013) Negar Fani et al.   JAMA Psychiatry

Interaction Between FKBP5 and Childhood Trauma and Risk of Aggressive Behavior

(2012) Laura Bevilacqua   ARCHIVES OF GENERAL PSYCHIATRY

Functional diversity and pharmacological profiles of the FKBPs and their complexes with small natural ligands

(2012) Andrzej Galat   CELLULAR AND MOLECULAR LIFE SCIENCES

The Prospect of FKBP51 as a Drug Target

(2012) Mathias V. Schmidt et al.   ChemMedChem

Prenatal and Perinatal Environmental Influences on the Human Fetal and Placental Epigenome

(2012) K Hogg et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Homeostasis and the Importance for a Balance Between AKT/mTOR Activity and Intracellular Signaling

(2012) D. A. Altomare et al.   CURRENT MEDICINAL CHEMISTRY

FKBP5and emotional neglect interact to predict individual differences in amygdala reactivity

(2012) M. G. White et al.   GENES BRAIN AND BEHAVIOR

The mTOR Signaling Pathway in the Brain: Focus on Epilepsy and Epileptogenesis

(2012) Emilio Russo et al.   MOLECULAR NEUROBIOLOGY

Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

(2012) Julia C. Lemos et al.   NATURE

Neurobiology of resilience

(2012) Scott J Russo et al.   NATURE NEUROSCIENCE

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Genetic architectures of psychiatric disorders: the emerging picture and its implications

(2012) Patrick F. Sullivan et al.   NATURE REVIEWS GENETICS

Dexamethasone Stimulated Gene Expression in Peripheral Blood is a Sensitive Marker for Glucocorticoid Receptor Resistance in Depressed Patients

(2012) Andreas Menke et al.   NEUROPSYCHOPHARMACOLOGY

Cell-type specific deletion of GABA(A) 1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction

(2012) G. M. Gafford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neural sensitivity to sex steroids predicts individual differences in aggression: implications for behavioural evolution

(2012) K. A. Rosvall et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Aberrant stress hormone receptor balance in the human prefrontal cortex and hypothalamic paraventricular nucleus of depressed patients

(2012) Xin-Rui Qi et al.   PSYCHONEUROENDOCRINOLOGY

Higher FKBP5, COMT, CHRNA5, and CRHR1 allele burdens are associated with PTSD and interact with trauma exposure: implications for neuropsychiatric research and treatment

(2012) Joseph Boscarino et al.   Neuropsychiatric Disease and Treatment

A Critical Review of the First 10 Years of Candidate Gene-by-Environment Interaction Research in Psychiatry

(2011) Laramie E. Duncan et al.   AMERICAN JOURNAL OF PSYCHIATRY

Interaction ofFKBP5Gene Variants and Adverse Life Events in Predicting Depression Onset: Results From a 10-Year Prospective Community Study

(2011) Petra Zimmermann et al.   AMERICAN JOURNAL OF PSYCHIATRY

Using Polymorphisms in FKBP5 to Define Biologically Distinct Subtypes of Posttraumatic Stress Disorder

(2011) Divya Mehta   ARCHIVES OF GENERAL PSYCHIATRY

The Serotonin Transporter Promoter Variant (5-HTTLPR), Stress, and Depression Meta-analysis Revisited

(2011) Katja Karg et al.   ARCHIVES OF GENERAL PSYCHIATRY

FK506 Binding Protein 5 Shapes Stress Responsiveness: Modulation of Neuroendocrine Reactivity and Coping Behavior

(2011) Chadi Touma et al.   BIOLOGICAL PSYCHIATRY

Corticosteroid-induced gene expression in allergen-challenged asthmatic subjects taking inhaled budesonide

(2011) MM Kelly et al.   BRITISH JOURNAL OF PHARMACOLOGY

Steroid up-regulation of FKBP51 and its role in hormone signaling

(2011) Tiina Jääskeläinen et al.   CURRENT OPINION IN PHARMACOLOGY

FKBP51 and the NF-κB regulatory pathway in cancer

(2011) Simona Romano et al.   CURRENT OPINION IN PHARMACOLOGY

FKBP51—a selective modulator of glucocorticoid and androgen sensitivity

(2011) Lance A Stechschulte et al.   CURRENT OPINION IN PHARMACOLOGY

FKBP51 regulation of AKT/protein kinase B phosphorylation

(2011) Liewei Wang   CURRENT OPINION IN PHARMACOLOGY

Stress, habits, and drug addiction: A psychoneuroendocrinological perspective.

(2011) Lars Schwabe et al.   EXPERIMENTAL AND CLINICAL PSYCHOPHARMACOLOGY

Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

A novel application of pattern recognition for accurate SNP and indel discovery from high-throughput data: Targeted resequencing of the glucocorticoid receptor co-chaperone FKBP5 in a Caucasian population

(2011) Linda L. Pelleymounter et al.   MOLECULAR GENETICS AND METABOLISM

Antidepressants increase human hippocampal neurogenesis by activating the glucocorticoid receptor

(2011) C Anacker et al.   MOLECULAR PSYCHIATRY

Neuropsin cleaves EphB2 in the amygdala to control anxiety

(2011) Benjamin K. Attwood et al.   NATURE

The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress

(2011) Jakob Hartmann et al.   NEUROPHARMACOLOGY

Moderation of Adult Depression by a Polymorphism in the FKBP5 Gene and Childhood Physical Abuse in the General Population

(2011) Katja Appel et al.   NEUROPSYCHOPHARMACOLOGY

Expression and Regulation of the Fkbp5 Gene in the Adult Mouse Brain

(2011) Sebastian H. Scharf et al.   PLoS One

Genetics of cortisol secretion and depressive symptoms: A candidate gene and genome wide association approach

(2011) Fleur P. Velders et al.   PSYCHONEUROENDOCRINOLOGY

A measure of glucocorticoid load provided by DNA methylation of Fkbp5 in mice

(2011) Richard S. Lee et al.   PSYCHOPHARMACOLOGY

Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1

(2011) D. Refojo et al.   SCIENCE

Genetic Sensitivity to the Environment: The Case of the Serotonin Transporter Gene and Its Implications for Studying Complex Diseases and Traits

(2010) Avshalom Caspi et al.   AMERICAN JOURNAL OF PSYCHIATRY

Epigenetic Transmission of the Impact of Early Stress Across Generations

(2010) Tamara B. Franklin et al.   BIOLOGICAL PSYCHIATRY

The nuclear factor- B-interleukin-6 signalling pathway mediating vascular inflammation

(2010) A. R. Brasier   CARDIOVASCULAR RESEARCH

Chronic Corticosterone Exposure Increases Expression and Decreases Deoxyribonucleic Acid Methylation ofFkbp5in Mice

(2010) Richard S. Lee et al.   ENDOCRINOLOGY

Rapid Glucocorticoid Receptor-Mediated Inhibition of Hypothalamic-Pituitary-Adrenal Ultradian Activity in Healthy Males

(2010) G. M. Russell et al.   JOURNAL OF NEUROSCIENCE

Glucocorticoid Receptor Activates PoisedFKBP51Locus through Long-Distance Interactions

(2010) Ville Paakinaho et al.   MOLECULAR ENDOCRINOLOGY

Cortical DNA methylation maintains remote memory

(2010) Courtney A Miller et al.   NATURE NEUROSCIENCE

FKBP5 and resistant attachment predict cortisol reactivity in infants: Gene–environment interaction

(2010) Maartje P.C.M. Luijk et al.   PSYCHONEUROENDOCRINOLOGY

Severe Psychological Stress in Elderly Individuals: A Proposed Model of Neurodegeneration and Its Implications

(2009) Magda Tsolaki et al.   American Journal of Alzheimers Disease and Other Dementias

Modification of the Association Between Serotonin Transporter Genotype and Risk of Posttraumatic Stress Disorder in Adults by County-Level Social Environment

(2009) K. C. Koenen et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Protective Effect of CRHR1 Gene Variants on the Development of Adult Depression Following Childhood Maltreatment

(2009) Guilherme Polanczyk et al.   ARCHIVES OF GENERAL PSYCHIATRY

Adverse Childhood Experiences and Adult Risk Factors for Age-Related Disease

(2009) Andrea Danese et al.   ARCHIVES OF PEDIATRICS & ADOLESCENT MEDICINE

The Influence of GABRA2, Childhood Trauma, and Their Interaction on Alcohol, Heroin, and Cocaine Dependence

(2009) Mary-Anne Enoch et al.   BIOLOGICAL PSYCHIATRY

The human glucocorticoid receptor: Molecular basis of biologic function

(2009) Nicolas C. Nicolaides et al.   STEROIDS

Influence of Child Abuse on Adult Depression

(2008) Rebekah G. Bradley et al.   ARCHIVES OF GENERAL PSYCHIATRY

Gene × Environment Interactions at the Serotonin Transporter Locus

(2008) Marcus R. Munafò et al.   BIOLOGICAL PSYCHIATRY

Diet and the epigenetic (re)programming of phenotypic differences in behavior

(2008) Patrick O. McGowan et al.   BRAIN RESEARCH

Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls

(2008) Marcus Ising et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Association of FKBP5 Polymorphisms and Childhood Abuse With Risk of Posttraumatic Stress Disorder Symptoms in Adults

(2008) Elisabeth B. Binder   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Psychosocial Stress and Psychosis. A Review of the Neurobiological Mechanisms and the Evidence for Gene-Stress Interaction

(2008) R. van Winkel et al.   SCHIZOPHRENIA BULLETIN