Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor
出版年份 2014 全文链接
标题
Recent advances in the molecular mechanisms determining tissue sensitivity to glucocorticoids: novel mutations, circadian rhythm and ligand-induced repression of the human glucocorticoid receptor
作者
关键词
Glucocorticoid receptor, Glucocorticoid resistance, Glucocorticoid hypersensitivity, Glucocorticoid signal transduction
出版物
BMC Endocrine Disorders
Volume 14, Issue 1, Pages -
出版商
Springer Nature
发表日期
2014-08-25
DOI
10.1186/1472-6823-14-71
参考文献
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- (2014) Nicolas C. Nicolaides et al. Annals of the New York Academy of Sciences
- A Novel Point Mutation of the Human Glucocorticoid Receptor Gene Causes Primary Generalized Glucocorticoid Resistance Through Impaired Interaction With the LXXLL Motif of the p160 Coactivators: Dissociation of the Transactivating and Transreppressive Activities
- (2014) Nicolas C. Nicolaides et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Modulation of glucocorticoid receptor induction properties by core circadian clock proteins
- (2014) Dong-Hee Han et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Genetic variation in FKBP5 associated with the extent of stress hormone dysregulation in major depression
- (2013) A. Menke et al. GENES BRAIN AND BEHAVIOR
- A Novel Point Mutation in the DNA-Binding Domain (DBD) of the Human Glucocorticoid Receptor Causes Primary Generalized Glucocorticoid Resistance by Disrupting the Hydrophobic Structure of its DBD
- (2013) Michael L. Roberts et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Ligand-Induced Repression of the Glucocorticoid Receptor Gene Is Mediated by an NCoR1 Repression Complex Formed by Long-Range Chromatin Interactions with Intragenic Glucocorticoid Response Elements
- (2013) Sivapriya Ramamoorthy et al. MOLECULAR AND CELLULAR BIOLOGY
- Determinants of the Heightened Activity of Glucocorticoid Receptor Translational Isoforms
- (2013) Ingrid K. Bender et al. MOLECULAR ENDOCRINOLOGY
- Circulating cortisol-associated signature of glucocorticoid-related gene expression in subcutaneous fat of obese subjects
- (2013) Maria G. Pavlatou et al. Obesity
- Differential targeting of brain stress circuits with a selective glucocorticoid receptor modulator
- (2013) I. Zalachoras et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role for the kinase SGK1 in stress, depression, and glucocorticoid effects on hippocampal neurogenesis
- (2013) C. Anacker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior
- (2012) C P Fitzsimons et al. MOLECULAR PSYCHIATRY
- Enhanced Steroid Response of a Human Glucocorticoid Receptor Splice Variant
- (2012) Aaron C. Baker et al. SHOCK
- The Origin of Glucocorticoid Hormone Oscillations
- (2012) Jamie J. Walker et al. PLOS BIOLOGY
- Q&A: Primary generalized glucocorticoid resistance
- (2011) George Chrousos BMC Medicine
- Widespread Negative Response Elements Mediate Direct Repression by Agonist- Liganded Glucocorticoid Receptor
- (2011) Milan Surjit et al. CELL
- Primary Generalized Glucocorticoid Resistance and Hypersensitivity
- (2011) Evangelia Charmandari Hormone Research in Paediatrics
- Rapid non-genomic effects of corticosteroids and their role in the central stress response
- (2011) Femke L Groeneweg et al. JOURNAL OF ENDOCRINOLOGY
- The involvement of FK506-binding protein 51 (FKBP5) in the behavioral and neuroendocrine effects of chronic social defeat stress
- (2011) Jakob Hartmann et al. NEUROPHARMACOLOGY
- Peripheral CLOCK Regulates Target-Tissue Glucocorticoid Receptor Transcriptional Activity in a Circadian Fashion in Man
- (2011) Evangelia Charmandari et al. PLoS One
- Novel Hyperactive Glucocorticoid Receptor Isoform Identified Within a Human Population
- (2011) Kelly Tung et al. SHOCK
- Chrousos syndrome: a seminal report, a phylogenetic enigma and the clinical implications of glucocorticoid signalling changes
- (2010) Evangelia Charmandari et al. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
- Cellular Processing of the Glucocorticoid Receptor Gene and Protein: New Mechanisms for Generating Tissue-specific Actions of Glucocorticoids
- (2010) Robert H. Oakley et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- A Novel Point Mutation in Helix 10 of the Human Glucocorticoid Receptor Causes Generalized Glucocorticoid Resistance by Disrupting the Structure of the Ligand-Binding Domain
- (2010) Nancy Nader et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Encoding and Decoding Mechanisms of Pulsatile Hormone Secretion
- (2010) J. J. Walker et al. JOURNAL OF NEUROENDOCRINOLOGY
- Origin of ultradian pulsatility in the hypothalamic-pituitary-adrenal axis
- (2010) J. J. Walker et al. PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: Implication for the stress response
- (2010) Nienke van Leeuwen et al. PSYCHONEUROENDOCRINOLOGY
- Interactions of the circadian CLOCK system and the HPA axis
- (2010) Nancy Nader et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Glucocorticoid Signaling in the Cell
- (2009) George P. Chrousos et al. Annals of the New York Academy of Sciences
- MicroRNA 18 and 124a Down-Regulate the Glucocorticoid Receptor: Implications for Glucocorticoid Responsiveness in the Brain
- (2009) Erno Vreugdenhil et al. ENDOCRINOLOGY
- Circadian rhythm transcription factor CLOCK regulates the transcriptional activity of the glucocorticoid receptor by acetylating its hinge region lysine cluster: potential physiological implications
- (2009) Nancy Nader et al. FASEB JOURNAL
- Neonatal Complete Generalized Glucocorticoid Resistance and Growth Hormone Deficiency Caused by a Novel Homozygous Mutation in Helix 12 of the Ligand Binding Domain of the Glucocorticoid Receptor Gene (NR3C1)
- (2009) Sarah K. McMahon et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription
- (2009) Diana A. Stavreva et al. NATURE CELL BIOLOGY
- Steroid receptor coactivator-1 is necessary for regulation of corticotropin-releasing hormone by chronic stress and glucocorticoids
- (2009) S. Lachize et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The human glucocorticoid receptor: Molecular basis of biologic function
- (2009) Nicolas C. Nicolaides et al. STEROIDS
- Association of SGK1 Gene Polymorphisms with Type 2 Diabetes
- (2008) Matthias Schwab et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Characterization of the vulnerability to repeated stress in Fischer 344 rats: possible involvement of microRNA-mediated down-regulation of the glucocorticoid receptor
- (2008) Shusaku Uchida et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Generalized Glucocorticoid Resistance: Clinical Aspects, Molecular Mechanisms, and Implications of a Rare Genetic Disorder
- (2008) Evangelia Charmandari et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- A Novel Point Mutation in the Amino Terminal Domain of the Human Glucocorticoid Receptor (hGR) Gene Enhancing hGR-Mediated Gene Expression
- (2008) Evangelia Charmandari et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- The genetics of mammalian circadian order and disorder: implications for physiology and disease
- (2008) Joseph S. Takahashi et al. NATURE REVIEWS GENETICS
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