Activation of mGluR5 Attenuates Microglial Activation and Neuronal Apoptosis in Early Brain Injury After Experimental Subarachnoid Hemorrhage in Rats

Cysteamine Alleviates Early Brain Injury Via Reducing Oxidative Stress and Apoptosis in a Rat Experimental Subarachnoid Hemorrhage Model

(2014) Zong-yong Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Carnosine Attenuates Early Brain Injury Through Its Antioxidative and Anti-apoptotic Effects in a Rat Experimental Subarachnoid Hemorrhage Model

(2014) Zong-yong Zhang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Activation of mGluR5 Attenuates NMDA-Induced Neurotoxicity through Disruption of the NMDAR-PSD-95 Complex and Preservation of Mitochondrial Function in Differentiated PC12 Cells

(2014) Shu-Hui Dai et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A novel technique for morphometric quantification of subarachnoid hemorrhage-induced microglia activation

(2014) Benjamin A. Plog et al.   JOURNAL OF NEUROSCIENCE METHODS

Novel mGluR5 Positive Allosteric Modulator Improves Functional Recovery, Attenuates Neurodegeneration, and Alters Microglial Polarization after Experimental Traumatic Brain Injury

(2014) David J. Loane et al.   Neurotherapeutics

Neuroprotective Effect of Hydrogen-Rich Saline against Neurologic Damage and Apoptosis in Early Brain Injury following Subarachnoid Hemorrhage: Possible Role of the Akt/GSK3β Signaling Pathway

(2014) Yuan Hong et al.   PLoS One

P2X7 Receptor Antagonism Inhibits p38 Mitogen-Activated Protein Kinase Activation and Ameliorates Neuronal Apoptosis After Subarachnoid Hemorrhage in Rats

(2013) Sheng Chen et al.   CRITICAL CARE MEDICINE

The role of microglia and the TLR4 pathway in neuronal apoptosis and vasospasm after subarachnoid hemorrhage

(2013) Khalid A Hanafy   Journal of Neuroinflammation

Melatonin-enhanced autophagy protects against neural apoptosis via a mitochondrial pathway in early brain injury following a subarachnoid hemorrhage

(2013) Jingyin Chen et al.   JOURNAL OF PINEAL RESEARCH

Delayed neurological deterioration after subarachnoid haemorrhage

(2013) R. Loch Macdonald   Nature Reviews Neurology

Controversies and evolving new mechanisms in subarachnoid hemorrhage

(2013) Sheng Chen et al.   PROGRESS IN NEUROBIOLOGY

Early Brain Injury, an Evolving Frontier in Subarachnoid Hemorrhage Research

(2013) Mutsumi Fujii et al.   Translational Stroke Research

Activation of metabotropic glutamate receptor 5 reduces the secondary brain injury after traumatic brain injury in rats

(2012) Jia-Wei Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Delayed mGluR5 activation limits neuroinflammation and neurodegeneration after traumatic brain injury

(2012) Kimberly R Byrnes et al.   Journal of Neuroinflammation

Activation of mGluR5 and Inhibition of NADPH Oxidase Improves Functional Recovery after Traumatic Brain Injury

(2012) David J. Loane et al.   JOURNAL OF NEUROTRAUMA

Protective Effects of mGluR5 Positive Modulators Against Traumatic Neuronal Injury Through PKC-Dependent Activation of MEK/ERK Pathway

(2012) Tao Chen et al.   NEUROCHEMICAL RESEARCH

Metabotropic glutamate receptors in neurodegeneration/neuroprotection: Still a hot topic?

(2012) Filippo Caraci et al.   NEUROCHEMISTRY INTERNATIONAL

The importance of early brain injury after subarachnoid hemorrhage

(2012) Fatima A. Sehba et al.   PROGRESS IN NEUROBIOLOGY

The increased expression of metabotropic glutamate receptor 5 in subventricular zone neural progenitor cells and enhanced neurogenesis in a rat model of intracerebral hemorrhage

(2011) X. Xu et al.   NEUROSCIENCE

Interdomain movements in metabotropic glutamate receptor activation

(2011) S. Huang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metabotropic Glutamate Receptors: Physiology, Pharmacology, and Disease

(2010) Colleen M. Niswender et al.   Annual Review of Pharmacology and Toxicology

Neuroinflammation is associated with changes in glial mGluR5 expression and the development of neonatal excitotoxic lesions

(2010) Janelle Drouin-Ouellet et al.   GLIA

Discovery of Novel Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Reveals Chemical and Functional Diversity and In Vivo Activity in Rat Behavioral Models of Anxiolytic and Antipsychotic Activity

(2010) A. L. Rodriguez et al.   MOLECULAR PHARMACOLOGY

Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents

(2009) Kimberly R. Byrnes et al.   ANNALS OF NEUROLOGY

Activation of Metabotropic Glutamate Receptor 5 Modulates Microglial Reactivity and Neurotoxicity by Inhibiting NADPH Oxidase

(2009) David J. Loane et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Metabotropic glutamate receptor 5 activation inhibits microglial associated inflammation and neurotoxicity

(2008) Kimberly R. Byrnes et al.   GLIA

Metabotropic glutamate receptors as targets for multipotential treatment of neurological disorders

(2008) Kimberly R. Byrnes et al.   Neurotherapeutics

A new grading system evaluating bleeding scale in filament perforation subarachnoid hemorrhage rat model

(2007) Takashi Sugawara et al.   JOURNAL OF NEUROSCIENCE METHODS