Lys-63-linked Ubiquitination by E3 Ubiquitin Ligase Nedd4-1 Facilitates Endosomal Sequestration of Internalized α-Synuclein
出版年份 2014 全文链接
标题
Lys-63-linked Ubiquitination by E3 Ubiquitin Ligase Nedd4-1 Facilitates Endosomal Sequestration of Internalized α-Synuclein
作者
关键词
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出版物
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 289, Issue 26, Pages 18137-18151
出版商
American Society for Biochemistry & Molecular Biology (ASBMB)
发表日期
2014-05-16
DOI
10.1074/jbc.m113.529461
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease
- (2014) Sian E. Davies et al. NEUROBIOLOGY OF DISEASE
- Serine 129 phosphorylation of membrane-associated α-synuclein modulates dopamine transporter function in a G protein–coupled receptor kinase–dependent manner
- (2013) Susumu Hara et al. MOLECULAR BIOLOGY OF THE CELL
- Alpha-Synuclein Induces Lysosomal Rupture and Cathepsin Dependent Reactive Oxygen Species Following Endocytosis
- (2013) David Freeman et al. PLoS One
- Yeast Reveal a "Druggable" Rsp5/Nedd4 Network that Ameliorates -Synuclein Toxicity in Neurons
- (2013) D. F. Tardiff et al. SCIENCE
- Role of α-synuclein penetration into the membrane in the mechanisms of oligomer pore formation
- (2012) Igor F. Tsigelny et al. FEBS Journal
- Suppression of dynamin GTPase decreases α-synuclein uptake by neuronal and oligodendroglial cells: a potent therapeutic target for synucleinopathy
- (2012) Masatoshi Konno et al. Molecular Neurodegeneration
- The many faces of α-synuclein: from structure and toxicity to therapeutic target
- (2012) Hilal A. Lashuel et al. NATURE REVIEWS NEUROSCIENCE
- Localization of CHMP2B-immunoreactivity in the brainstem of Lewy body disease
- (2012) Takashi Kurashige et al. NEUROPATHOLOGY
- Endosomal sorting related protein CHMP2B is localized in Lewy bodies and glial cytoplasmic inclusions in α-synucleinopathy
- (2012) Satoshi Tanikawa et al. NEUROSCIENCE LETTERS
- Nedd4-mediated AMPA receptor ubiquitination regulates receptor turnover and trafficking
- (2011) Amy Lin et al. JOURNAL OF NEUROCHEMISTRY
- The AAA-ATPase VPS4 Regulates Extracellular Secretion and Lysosomal Targeting of α-Synuclein
- (2011) Takafumi Hasegawa et al. PLoS One
- Ubiquitin ligase Nedd4 promotes -synuclein degradation by the endosomal-lysosomal pathway
- (2011) G. K. Tofaris et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Arrestin domain-containing protein 3 recruits the NEDD4 E3 ligase to mediate ubiquitination of the β2-adrenergic receptor
- (2010) Joseph F Nabhan et al. EMBO REPORTS
- Calcium Activates Nedd4 E3 Ubiquitin Ligases by Releasing the C2 Domain-mediated Auto-inhibition
- (2010) Jian Wang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Lipid-binding Domain of Wild Type and Mutant α-Synuclein
- (2010) Elka R. Georgieva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Membrane Curvature Induction and Tubulation Are Common Features of Synucleins and Apolipoproteins
- (2010) Jobin Varkey et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Aggregation of α-Synuclein in S. cerevisiae is Associated with Defects in Endosomal Trafficking and Phospholipid Biosynthesis
- (2010) James H. Soper et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Are synucleinopathies prion-like disorders?
- (2010) Elodie Angot et al. LANCET NEUROLOGY
- Cell-to-cell transmission of non-prion protein aggregates
- (2010) Seung-Jae Lee et al. Nature Reviews Neurology
- The ubiquitin code of yeast permease trafficking
- (2010) Elsa Lauwers et al. TRENDS IN CELL BIOLOGY
- K63-linked ubiquitin chains as a specific signal for protein sorting into the multivesicular body pathway
- (2009) Elsa Lauwers et al. JOURNAL OF CELL BIOLOGY
- Cytoplasmic penetration and persistent infection of mammalian cells by polyglutamine aggregates
- (2009) Pei-Hsien Ren et al. NATURE CELL BIOLOGY
- Physiological functions of the HECT family of ubiquitin ligases
- (2009) Daniela Rotin et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inclusion formation and neuronal cell death through neuron-to-neuron transmission of -synuclein
- (2009) P. Desplats et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Assembly-dependent endocytosis and clearance of extracellular a-synuclein
- (2008) He-Jin Lee et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Serine 129 Phosphorylation of α-Synuclein Induces Unfolded Protein Response-mediated Cell Death
- (2008) Naoto Sugeno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- CHIP Targets Toxic α-Synuclein Oligomers for Degradation
- (2008) Julie E. Tetzlaff et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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