Inhibited Insulin Signaling in Mouse Hepatocytes Is Associated with Increased Phosphatidic Acid but Not Diacylglycerol

Glycerol-3-phosphate acyltransferase-4-deficient mice are protected from diet-induced insulin resistance by the enhanced association of mTOR and rictor

(2014) Chongben Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Abrogating Monoacylglycerol Acyltransferase Activity in Liver Improves Glucose Tolerance and Hepatic Insulin Signaling in Obese Mice

(2014) A. M. Hall et al.   DIABETES

Phospholipase D and the Maintenance of Phosphatidic Acid Levels for Regulation of Mammalian Target of Rapamycin (mTOR)

(2014) David A. Foster et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phospholipase D Signaling Mediates Reactive Oxygen Species-Induced Lung Endothelial Barrier Dysfunction

(2014) Peter V. Usatyuk et al.   Pulmonary Circulation

Lipid signals and insulin resistance

(2013) Chongben Zhang et al.   Clinical Lipidology

Triacylglycerol Synthesis Enzymes Mediate Lipid Droplet Growth by Relocalizing from the ER to Lipid Droplets

(2013) Florian Wilfling et al.   DEVELOPMENTAL CELL

Selective hepatic insulin resistance in a murine model heterozygous for a mitochondrial trifunctional protein defect

(2013) R. Scott Rector et al.   HEPATOLOGY

Nonalcoholic fatty liver disease, hepatic insulin resistance, and type 2 Diabetes

(2013) Andreas L. Birkenfeld et al.   HEPATOLOGY

CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

(2013) J. L. Cantley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance

(2012) François R. Jornayvaz et al.   Cell Metabolism

The Problem of Establishing Relationships between Hepatic Steatosis and Hepatic Insulin Resistance

(2012) Robert V. Farese et al.   Cell Metabolism

Intrahepatic Diacylglycerol Content Is Associated With Hepatic Insulin Resistance in Obese Subjects

(2012) Faidon Magkos et al.   GASTROENTEROLOGY

Glycerolipid signals alter mTOR complex 2 (mTORC2) to diminish insulin signaling

(2012) C. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTOR signaling: PLD takes center stage

(2011) Yuting Sun et al.   CELL CYCLE

Regulation and Functions of Diacylglycerol Kinases

(2011) Yulia V. Shulga et al.   CHEMICAL REVIEWS

Mammalian Triacylglycerol Metabolism: Synthesis, Lipolysis, and Signaling

(2011) Rosalind A. Coleman et al.   CHEMICAL REVIEWS

Hepatic acyl-CoA:diacylglcyerol acyltransferase (DGAT) overexpression, diacylglycerol, and insulin sensitivity

(2011) M. Monetti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Expression and regulation of GPAT isoforms in cultured human keratinocytes and rodent epidermis

(2010) Biao Lu et al.   JOURNAL OF LIPID RESEARCH

Enzymatic activities of the human AGPAT isoform 3 and isoform 5: localization of AGPAT5 to mitochondria

(2010) Sneha S. Prasad et al.   JOURNAL OF LIPID RESEARCH

Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance

(2008) Alexander V. Chibalin et al.   CELL

Protein Kinase C-ϵ Regulates Sphingosine 1-Phosphate-mediated Migration of Human Lung Endothelial Cells through Activation of Phospholipase D2, Protein Kinase C-ζ, and Rac1

(2008) Irina Gorshkova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AGPAT6 Is a Novel Microsomal Glycerol-3-phosphate Acyltransferase

(2008) Yan Qun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

S6K Directly Phosphorylates IRS-1 on Ser-270 to Promote Insulin Resistance in Response to TNF-α Signaling through IKK2

(2008) Jin Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a novelsn-glycerol-3-phosphate acyltransferase isoform, GPAT4, as the enzyme deficient inAgpat6−/−mice

(2008) Cynthia A. Nagle et al.   JOURNAL OF LIPID RESEARCH

Blocking VLDL secretion causes hepatic steatosis but does not affect peripheral lipid stores or insulin sensitivity in mice

(2008) Kaori Minehira et al.   JOURNAL OF LIPID RESEARCH

Regulation of mTORC1 and mTORC2 Complex Assembly by Phosphatidic Acid: Competition with Rapamycin

(2008) A. Toschi et al.   MOLECULAR AND CELLULAR BIOLOGY

Lipid Messenger, Diacylglycerol, and its Regulator, Diacylglycerol Kinase, in Cells, Organs, and Animals: History and Perspective

(2008) Kaoru Goto et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

Diacylglycerol kinases: at the hub of cell signalling

(2007) Isabel Mérida et al.   BIOCHEMICAL JOURNAL