CGI-58 knockdown sequesters diacylglycerols in lipid droplets/ER-preventing diacylglycerol-mediated hepatic insulin resistance

Mechanisms for Insulin Resistance: Common Threads and Missing Links

(2012) Varman T. Samuel et al.   CELL

Diacylglycerol Activation of Protein Kinase Cε and Hepatic Insulin Resistance

(2012) François R. Jornayvaz et al.   Cell Metabolism

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

CGI-58/ABHD5-Derived Signaling Lipids Regulate Systemic Inflammation and Insulin Action

(2012) C. C. Lord et al.   DIABETES

Localisation and composition of skeletal muscle diacylglycerol predicts insulin resistance in humans

(2012) B. C. Bergman et al.   DIABETOLOGIA

Studies on the Substrate and Stereo/Regioselectivity of Adipose Triglyceride Lipase, Hormone-sensitive Lipase, and Diacylglycerol-O-acyltransferases

(2012) Thomas O. Eichmann et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The lipogenic transcription factor ChREBP dissociates hepatic steatosis from insulin resistance in mice and humans

(2012) Fadila Benhamed et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatic Hdac3 promotes gluconeogenesis by repressing lipid synthesis and sequestration

(2012) Zheng Sun et al.   NATURE MEDICINE

Ceramides as modulators of cellular and whole-body metabolism

(2011) Benjamin T. Bikman et al.   JOURNAL OF CLINICAL INVESTIGATION

Cellular mechanism of insulin resistance in nonalcoholic fatty liver disease

(2011) N. Kumashiro et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Differential control of ATGL-mediated lipid droplet degradation by CGI-58 and G0S2

(2010) Xin Lu et al.   CELL CYCLE

Recent advances in nonalcoholic fatty liver disease

(2010) Onpan Cheung et al.   CURRENT OPINION IN GASTROENTEROLOGY

Targeting Ceramide Synthesis to Reverse Insulin Resistance

(2010) C. Schmitz-Peiffer   DIABETES

Identification of the lipid droplet targeting domain of the Cidea protein

(2010) Jennifer L. Christianson et al.   JOURNAL OF LIPID RESEARCH

CGI-58 knockdown in mice causes hepatic steatosis but prevents diet-induced obesity and glucose intolerance

(2010) J. Mark Brown et al.   JOURNAL OF LIPID RESEARCH

Lipid-induced insulin resistance: unravelling the mechanism

(2010) Varman T Samuel et al.   LANCET

Adipose Triglyceride Lipase Deficiency Causes Tissue-specific Changes in Insulin Signaling

(2009) Petra C. Kienesberger et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Growth Retardation, Impaired Triacylglycerol Catabolism, Hepatic Steatosis, and Lethal Skin Barrier Defect in Mice Lacking Comparative Gene Identification-58 (CGI-58)

(2009) Franz P. W. Radner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adipocytokines and the Metabolic Complications of Obesity

(2008) Neda Rasouli et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Lipolysis and the integrated physiology of lipid energy metabolism

(2008) Shupei Wang et al.   MOLECULAR GENETICS AND METABOLISM

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(2008) Katja Rabe et al.   MOLECULAR MEDICINE

Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

(2008) Adilson Guilherme et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY