The Proteasome-associated Protein Ecm29 Inhibits Proteasomal ATPase Activity andin VivoProtein Degradation by the Proteasome

Molecular Architecture and Assembly of the Eukaryotic Proteasome

(2013) Robert J. Tomko et al.   Annual Review of Biochemistry

Proteasome Regulation by ADP-Ribosylation

(2013) Park F. Cho-Park et al.   CELL

The proteasome under the microscope: the regulatory particle in focus

(2013) Gabriel C Lander et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Reconfiguration of the proteasome during chaperone-mediated assembly

(2013) Soyeon Park et al.   NATURE

Conformational switching of the 26S proteasome enables substrate degradation

(2013) Mary E Matyskiela et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Functions of the 19S complex in proteasomal degradation

(2013) Chang-Wei Liu et al.   TRENDS IN BIOCHEMICAL SCIENCES

Stable Incorporation of ATPase Subunits into 19 S Regulatory Particle of Human Proteasome Requires Nucleotide Binding and C-terminal Tails

(2012) Seung-Hoon Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Functional Asymmetries of Proteasome Translocase Pore

(2012) Jenny Erales et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATP Binding by Proteasomal ATPases Regulates Cellular Assembly and Substrate-induced Functions of the 26 S Proteasome

(2012) Young-Chan Kim et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular Model of the Human 26S Proteasome

(2012) Paula C.A. da Fonseca et al.   MOLECULAR CELL

Dual functions of the Hsm3 protein in chaperoning and scaffolding regulatory particle subunits during the proteasome assembly

(2012) M.-B. Barrault et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach

(2012) K. Lasker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Near-atomic resolution structural model of the yeast 26S proteasome

(2012) F. Beck et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of S5b/PSMD5 in Proteasome Inhibition Caused by TNF-α/NFκB in Higher Eukaryotes

(2012) Sang Mi Shim et al.   Cell Reports

ATP Binds to Proteasomal ATPases in Pairs with Distinct Functional Effects, Implying an Ordered Reaction Cycle

(2011) David M. Smith et al.   CELL

Cellular stress response pathways and ageing: intricate molecular relationships

(2011) Nikos Kourtis et al.   EMBO JOURNAL

Structural Defects in the Regulatory Particle-Core Particle Interface of the Proteasome Induce a Novel Proteasome Stress Response

(2011) Soyeon Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Loss of Rpt5 Protein Interactions with the Core Particle and Nas2 Protein Causes the Formation of Faulty Proteasomes That Are Inhibited by Ecm29 Protein

(2011) Stella Yu-Chien Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dependence of Proteasome Processing Rate on Substrate Unfolding

(2011) Allen Henderson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Not4 E3 Ligase Contributes to Proteasome Assembly and Functional Integrity in Part through Ecm29

(2011) O. O. Panasenko et al.   MOLECULAR AND CELLULAR BIOLOGY

Inhibition of proteasome deubiquitinating activity as a new cancer therapy

(2011) Pádraig D'Arcy et al.   NATURE MEDICINE

An asymmetric interface between the regulatory and core particles of the proteasome

(2011) Geng Tian et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

UBLCP1 is a 26S proteasome phosphatase that regulates nuclear proteasome activity

(2011) X. Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ASK1 Negatively Regulates the 26 S Proteasome

(2010) Ji Won Um et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Protein Interaction Network for Ecm29 Links the 26 S Proteasome to Molecular Motors and Endosomal Components

(2010) Carlos Gorbea et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ecm29 Fulfils Quality Control Functions in Proteasome Assembly

(2010) Andrea Lehmann et al.   MOLECULAR CELL

Enhancement of proteasome activity by a small-molecule inhibitor of USP14

(2010) Byung-Hoon Lee et al.   NATURE

Regulation of the 26S Proteasome Complex During Oxidative Stress

(2010) X. Wang et al.   Science Signaling

Assembly, structure, and function of the 26S proteasome

(2010) Lynn Bedford et al.   TRENDS IN CELL BIOLOGY

Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome

(2009) Daniel Finley   Annual Review of Biochemistry

Structural Models for Interactions between the 20S Proteasome and Its PAN/19S Activators

(2009) Beth M. Stadtmueller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ubiquitinated Proteins Activate the Proteasome by Binding to Usp14/Ubp6, which Causes 20S Gate Opening

(2009) Andreas Peth et al.   MOLECULAR CELL

Chaperone-mediated pathway of proteasome regulatory particle assembly

(2009) Jeroen Roelofs et al.   NATURE

Hexameric assembly of the proteasomal ATPases is templated through their C termini

(2009) Soyeon Park et al.   NATURE

Targeting proteins for degradation

(2009) Erin K Schrader et al.   Nature Chemical Biology

A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel

(2009) Pawel A. Osmulski et al.   STRUCTURE

Proteasome Inhibitors in Cancer Therapy: Lessons from the First Decade

(2008) R. Z. Orlowski et al.   CLINICAL CANCER RESEARCH

Differential Roles of the COOH Termini of AAA Subunits of PA700 (19 S Regulator) in Asymmetric Assembly and Activation of the 26 S Proteasome

(2008) Thomas G. Gillette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mechanism of Gate Opening in the 20S Proteasome by the Proteasomal ATPases

(2008) Julius Rabl et al.   MOLECULAR CELL